Seasonal effects of influenza on mortality in a subtropical city. - RIIP - Réseau International des Instituts Pasteur Accéder directement au contenu
Article Dans Une Revue BMC Infectious Diseases Année : 2009

Seasonal effects of influenza on mortality in a subtropical city.

Résumé

BACKGROUND: Influenza has been associated with a heavy burden of mortality. In tropical or subtropical regions where influenza viruses circulate in the community most of the year, it is possible that there are seasonal variations in the effects of influenza on mortality, because of periodic changes in environment and host factors as well as the frequent emergence of new antigenically drifted virus strains. In this paper we explored this seasonal effect of influenza. METHODS: A time-varying coefficient Poisson regression model was fitted to the weekly numbers of mortality of Hong Kong from 1996 to 2002. Excess risks associated with influenza were calculated to assess the seasonal effects of influenza. RESULTS: We demonstrated that the effects of influenza were higher in winter and late spring/early summer than other seasons. The two-peak pattern of seasonal effects of influenza was found for cardio-respiratory disease and sub-categories pneumonia and influenza, chronic obstructive pulmonary disease, cerebrovascular diseases and ischemic heart disease as well as for all-cause deaths. CONCLUSION: The results provide insight into the possibility that seasonal factors may have impact on virulence of influenza besides their effects on virus transmission. The results warrant further studies into the mechanisms behind the seasonal effect of influenza.

Domaines

Virologie
Fichier principal
Vignette du fichier
Yang_BMC_InfectDis_2009.pdf (437.34 Ko) Télécharger le fichier
Origine : Fichiers éditeurs autorisés sur une archive ouverte
Loading...

Dates et versions

pasteur-00588926 , version 1 (27-04-2011)

Identifiants

Citer

Lin Yang, Chit Ming Wong, King Pan Chan, Patsy Yuen Kwan Chau, Chun Quan Ou, et al.. Seasonal effects of influenza on mortality in a subtropical city.. BMC Infectious Diseases, 2009, 9, pp.133. ⟨10.1186/1471-2334-9-133⟩. ⟨pasteur-00588926⟩

Collections

RIIP RIIP_HONGKONG
131 Consultations
915 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More