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Article Dans Une Revue PLoS Neglected Tropical Diseases Année : 2013

Understanding the persistence of plague foci in Madagascar.

Résumé

Plague, a zoonosis caused by Yersinia pestis, is still found in Africa, Asia, and the Americas. Madagascar reports almost one third of the cases worldwide. Y. pestis can be encountered in three very different types of foci: urban, rural, and sylvatic. Flea vector and wild rodent host population dynamics are tightly correlated with modulation of climatic conditions, an association that could be crucial for both the maintenance of foci and human plague epidemics. The black rat Rattus rattus, the main host of Y. pestis in Madagascar, is found to exhibit high resistance to plague in endemic areas, opposing the concept of high mortality rates among rats exposed to the infection. Also, endemic fleas could play an essential role in maintenance of the foci. This review discusses recent advances in the understanding of the role of these factors as well as human behavior in the persistence of plague in Madagascar.
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Dates et versions

pasteur-00946701 , version 1 (14-02-2014)

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Voahangy Andrianaivoarimanana, Katharina Kreppel, Nohal Elissa, Jean-Marc Duplantier, Elisabeth Carniel, et al.. Understanding the persistence of plague foci in Madagascar.. PLoS Neglected Tropical Diseases, 2013, 7 (11), pp.e2382. ⟨10.1371/journal.pntd.0002382⟩. ⟨pasteur-00946701⟩
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