First field evaluation of the optimized CE marked Abbott protocol for HIV RNA testing on dried blood spot in a routine clinical setting in Vietnam

Fabien Taieb (1, 2) , Tram Tran Hong (3) , Hien Thi Ho (4) , T .B. Nguyen (3) , Tram Pham Phuong (3) , Dung Viet Ta (4) , Nhung Le Thi Hong (3) , Hien Ba Pham (4) , Lan Thi Huong Nguyen (4) , Huong Thi Nguyen (4) , Thu Trang Nguyen (4) , Edouard Tuaillon (5) , Eric Delaporte (6) , Huong Le Thi (4) , Hau Tran Thi Bich (4) , Tuan Anh Nguyen (3) , Yoann Madec (2)

1 CRT - Centre de Recherche Translationnelle - Center for Translational Science
2 Epidémiologie des Maladies Emergentes - Emerging Diseases Epidemiology
3 NIHE - National Institute of Hygiene and Epidemiology [Hanoi, Vietnam]
4 Chercheur indépendant
5 Pathogénèse et contrôle des infections chroniques (PCCI)
6 TransVIHMI - Recherches Translationnelles sur le VIH et les maladies infectieuses endémiques et émergentes

Viral load (VL) monitoring of HIV-infected patients in decentralized areas is limited due to logistic constraints. Dried Blood Spots (DBS) offer the opportunity to collect samples in remote area which can be easily transferred and tested at a central laboratory. The MOVIDA (Monitoring Of Viral load In Decentralized Area) project evaluated the performance of VL measurements on DBS using the new CE marked optimized Abbott protocol.

Domaines: Maladies infectieuses; Ingénierie biomédicale; Santé publique et épidémiologie

Fabien Taieb, Tram Tran Hong, Hien Thi Ho, T .B. Nguyen, Tram Pham Phuong, et al.. First field evaluation of the optimized CE marked Abbott protocol for HIV RNA testing on dried blood spot in a routine clinical setting in Vietnam. PLoS ONE, 2018, 13 (2), pp.e0191920. ⟨10.1371/journal.pone.0191920⟩. ⟨hal-01890176⟩