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Journal articles
Multidrug-resistant Mycobacterium tuberculosis strain from Equatorial Guinea detected in Spain.
Abstract : This investigation focused on a specific Multidrug-Resistant (MDR) Mycobacterium tuberculosis strain from Equatorial Guinea that had been imported into Spain. Ten MDR isolates from as many patients from Equatorial Guinea were detected in Spain during 2000 through 2008. All the 10 isolates exhibited an identical genotypic pattern belonging to the Latin-American and Mediterranean (LAM) genotypic lineage of M. tuberculosis designated SIT177-LAM 9. Evidence of clonality was found for all the 10 isolates by different molecular epidemiology methods and mutations involved in drug resistance. The analysis of the RDRio deletion confirmed that the strain belonged to the major RDRio sublineage of the Latin-American and Mediterranean (LAM) genotypic lineage of M. tuberculosis which has disseminated globally.
Keywords :
Mycobacterium
Tuberculosis
Equatorial Guinea
Spain
Multidrug-Resistant
Epidemiology
Immigrants
Spoligotyping
MIRU-VNTR
IS6110-RFLP
SITVIT2
"Mycobacterium"
"Tuberculosis"
"Equatorial Guinea"
"Spain"
"Multidrug-Resistant"
"Epidemiology"
"Immigrants"
"Spoligotyping"
"MIRU-VNTR"
"IS6110-RFLP"
"SITVIT2"
Cited literature [10 references]
https://hal-riip.archives-ouvertes.fr/pasteur-00511967
Contributor : Nalin Rastogi Connect in order to contact the contributor
Submitted on : Thursday, August 26, 2010 - 6:10:52 PM
Last modification on : Monday, June 21, 2021 - 10:58:06 AM
Long-term archiving on: : Monday, November 29, 2010 - 12:03:52 PM
Contributor : Nalin Rastogi Connect in order to contact the contributor
Submitted on : Thursday, August 26, 2010 - 6:10:52 PM
Last modification on : Monday, June 21, 2021 - 10:58:06 AM
Long-term archiving on: : Monday, November 29, 2010 - 12:03:52 PM
File
MDRTB_EID2009.pdf
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