Evidence of recombination and genetic diversity in human rhinoviruses in children with acute respiratory infection.

Ting Huang (1) , Wei Wang (1) , Mael Bessaud (2) , Peijun Ren (1) , Jun Sheng (3) , Huajie Yan (3) , Jing Zhang (1) , Xin Lin (1) , Yongjin Wang (1) , Francis Delpeyroux (2) , Vincent Deubel (1)

1 Emerging Viruses
2 BVE - Biologie des Virus entériques
3 Shanghai Nanxiang Hospital

Our study showed a high diversity of HRV strains that cause bronchitis and pneumonia in children. A predominance of HRV-C over HRV-A and HRV-B was observed, and two subspecies of HRV-C were identified, the diversity of which seemed to be related to recombination with former HRV-A strains. None of the HRV-C strains appeared to have a higher clinical impact than HRV-A or HRV-B on respiratory compromise.

Domains: Life Sciences [q-bio]; Microbiology and Parasitology; Virology

Ting Huang, Wei Wang, Mael Bessaud, Peijun Ren, Jun Sheng, et al.. Evidence of recombination and genetic diversity in human rhinoviruses in children with acute respiratory infection.. PLoS ONE, 2009, 4 (7), pp.e6355. ⟨10.1371/journal.pone.0006355⟩. ⟨pasteur-00556072⟩