Service interruption on Monday 11 July from 12:30 to 13:00: all the sites of the CCSD (HAL, EpiSciences, SciencesConf, AureHAL) will be inaccessible (network hardware connection).
Skip to Main content Skip to Navigation
Journal articles

CagA and VacA polymorphisms are associated with distinct pathological features in Helicobacter pylori-infected adults with peptic ulcer and non-peptic ulcer disease.

Abstract : Polymorphic variability in Helicobacter pylori factors CagA and VacA contributes to bacterial virulence. The presence of one CagA EPIYA-C site is an independent risk factor for gastroduodenal ulceration (odds ratio [OR], 4.647; 95% confidence interval [CI], 2.037 to 10.602), while the presence of the vacA i1 allele is a risk factor for increased activity (OR, 5.310; 95% CI, 2.295 to 12.287) and severity of gastritis (OR, 3.862; 95% CI, 1.728 to 8.632).
Document type :
Journal articles
Complete list of metadata

https://hal-riip.archives-ouvertes.fr/pasteur-00583691
Contributor : Sébastien Breurec Connect in order to contact the contributor
Submitted on : Wednesday, April 6, 2011 - 12:18:27 PM
Last modification on : Monday, November 22, 2021 - 5:46:02 PM

Links full text

Identifiers

Collections

Citation

Effrosini G Panayotopoulou, Dionyssios N Sgouras, Konstantinos S Papadakos, Kalliopi Petraki, Sébastien Breurec, et al.. CagA and VacA polymorphisms are associated with distinct pathological features in Helicobacter pylori-infected adults with peptic ulcer and non-peptic ulcer disease.. Journal of Clinical Microbiology, American Society for Microbiology, 2010, 48 (6), pp.2237-9. ⟨10.1128/JCM.00662-10⟩. ⟨pasteur-00583691⟩

Share

Metrics

Record views

30