G. Smith, D. Vijaykrishna, J. Bahl, S. Lycett, M. Worobey et al., Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic, Nature, vol.22, issue.7250, pp.1122-1125, 2009.
DOI : 10.1038/nature08182

G. Neumann, T. Noda, and Y. Kawaoka, Emergence and pandemic potential of swine-origin H1N1 influenza virus, Nature, vol.367, issue.7249, pp.931-939, 2009.
DOI : 10.1038/nature08157

F. Dawood, S. Jain, L. Finelli, M. Shaw, S. Lindstrom et al., Emergence of a novel swine-origin influenza A (H1N1) virus in humans, N Engl J Med, vol.360, pp.2605-2615, 2009.

A. Kumar, R. Zarychanski, R. Pinto, D. Cook, J. Marshall et al., Critically Ill Patients With 2009 Influenza A(H1N1) Infection in Canada, Critically ill patients with 2009 influenza A(H1N1) infection in Canada, pp.1872-1879, 2009.
DOI : 10.1001/jama.2009.1496

K. Hancock, V. Veguilla, X. Lu, W. Zhong, E. Butler et al., Cross-Reactive Antibody Responses to the 2009 Pandemic H1N1 Influenza Virus, New England Journal of Medicine, vol.361, issue.20, pp.1945-1952, 2009.
DOI : 10.1056/NEJMoa0906453

V. Munster, E. De-wit, J. Van-den-brand, S. Herfst, E. Schrauwen et al., Pathogenesis and Transmission of Swine-Origin 2009 A(H1N1) Influenza Virus in Ferrets, Science, vol.325, pp.481-483, 2009.
DOI : 10.1126/science.1177127

T. Maines, A. Jayaraman, J. Belser, D. Wadford, C. Pappas et al., Transmission and Pathogenesis of Swine-Origin 2009 A(H1N1) Influenza Viruses in Ferrets and Mice, Science, vol.325, pp.484-487, 2009.
DOI : 10.1126/science.1177238

R. Childs, A. Palma, S. Wharton, T. Matrosovich, Y. Liu et al., Receptor-binding specificity of pandemic influenza A (H1N1) 2009 virus determined by carbohydrate microarray, Nature Biotechnology, vol.362, issue.9, pp.797-799, 2009.
DOI : 10.1038/nbt0909-797

M. Chan, C. Cheung, W. Chui, S. Tsao, J. Nicholls et al., Proinflammatory cytokine responses induced by influenza A (H5N1) viruses in primary human alveolar and bronchial epithelial cells, Respiratory Research, vol.431, issue.21, p.135, 2005.
DOI : 10.1038/nature02951

C. Cheung, L. Poon, A. Lau, W. Luk, Y. Lau et al., Induction of proinflammatory cytokines in human macrophages by influenza A (H5N1) viruses: a mechanism for the unusual severity of human disease?, The Lancet, vol.360, issue.9348, pp.1831-1837, 2002.
DOI : 10.1016/S0140-6736(02)11772-7

J. Kash, T. Tumpey, S. Proll, V. Carter, O. Perwitasari et al., Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus, Nature, vol.29, pp.578-581, 2006.
DOI : 10.1038/nature05181

L. Perrone, J. Plowden, A. Garcia-sastre, J. Katz, and T. Tumpey, H5N1 and 1918 Pandemic Influenza Virus Infection Results in Early and Excessive Infiltration of Macrophages and Neutrophils in the Lungs of Mice, PLoS Pathogens, vol.10, issue.652, p.1000115, 2008.
DOI : 10.1371/journal.ppat.1000115.t002

M. Chan, R. Chan, W. Yu, C. Ho, W. Chui et al., Influenza H5N1 virus infection of polarized human alveolar epithelial cells and lung microvascular endothelial cells, Respiratory Research, vol.37, issue.4, p.102, 2009.
DOI : 10.1016/j.humpath.2006.01.015

URL : https://hal.archives-ouvertes.fr/pasteur-00588916

J. Nicholls, M. Chan, W. Chan, H. Wong, C. Cheung et al., Tropism of avian influenza A (H5N1) in the upper and lower respiratory tract, Nature Medicine, vol.312, issue.2, pp.147-149, 2007.
DOI : 10.1038/nm1529

K. Kumari, S. Gulati, D. Smith, U. Gulati, R. Cummings et al., Receptor binding specificity of recent human H3N2 influenza viruses, Virology Journal, vol.4, issue.1, p.42, 2007.
DOI : 10.1186/1743-422X-4-42

R. Chan, M. Chan, A. Wong, R. Karamanska, A. Dell et al., DAS181 Inhibits H5N1 Influenza Virus Infection of Human Lung Tissues, Antimicrobial Agents and Chemotherapy, vol.53, issue.9, pp.1813935-3941, 2009.
DOI : 10.1128/AAC.00389-09

T. Gray, K. Guzman, C. Davis, L. Abdullah, and P. Nettesheim, Mucociliary differentiation of serially passaged normal human tracheobronchial epithelial cells., American Journal of Respiratory Cell and Molecular Biology, vol.14, issue.1, pp.104-112, 1996.
DOI : 10.1165/ajrcmb.14.1.8534481

G. Zhen, S. Park, L. Nguyenvu, M. Rodriguez, R. Barbeau et al., IL-13 and Epidermal Growth Factor Receptor Have Critical but Distinct Roles in Epithelial Cell Mucin Production, American Journal of Respiratory Cell and Molecular Biology, vol.36, issue.2, pp.244-253, 2007.
DOI : 10.1165/rcmb.2006-0180OC

S. Tsao, X. Wang, Y. Liu, Y. Cheung, H. Feng et al., Establishment of two immortalized nasopharyngeal epithelial cell lines using SV40 large T and HPV16E6/E7 viral oncogenes, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, vol.1590, issue.1-3, pp.150-158, 2002.
DOI : 10.1016/S0167-4889(02)00208-2

K. Shinya, M. Ebina, S. Yamada, M. Ono, N. Kasai et al., Avian flu: Influenza virus receptors in the human airway, Nature, vol.293, issue.7083, pp.435-436, 2006.
DOI : 10.1038/440435a

G. Karber, Beitrag zur kollektiven Behandlung pharmakologischer Reihenversuche, Naunyn-Schmiedebergs Archiv f??r Experimentelle Pathologie und Pharmakologie, vol.151, issue.4, pp.480-483, 1931.
DOI : 10.1007/BF01863914

J. Belser, D. Wadford, J. Xu, J. Katz, and T. Tumpey, Ocular Infection of Mice with Influenza A (H7) Viruses: a Site of Primary Replication and Spread to the Respiratory Tract, Journal of Virology, vol.83, issue.14, pp.7075-7084, 2009.
DOI : 10.1128/JVI.00535-09

M. Michaelis, J. Geiler, D. Klassert, H. Doerr, and J. Cinatl, Infection of Human Retinal Pigment Epithelial Cells with Influenza A Viruses, Investigative Opthalmology & Visual Science, vol.50, issue.11, pp.5419-5425, 2009.
DOI : 10.1167/iovs.09-3752

J. Nicholls, A. Bourne, H. Chen, Y. Guan, and J. Peiris, Sialic acid receptor detection in the human respiratory tract: evidence for widespread distribution of potential binding sites for human and avian influenza viruses, Respiratory Research, vol.80, issue.15, p.73, 2007.
DOI : 10.1128/JVI.02677-05

A. Terraciano, N. Wang, J. Schuman, G. Haffner, N. Panjwani et al., Sialyl Lewis X, Lewis X, and N-acetyllactosamine expression on normal and glaucomatous eyes, Current Eye Research, vol.261, issue.2, pp.73-78, 1999.
DOI : 10.1076/ceyr.18.2.73.5377

M. Berry, R. Ellingham, and A. Corfield, Polydispersity of normal human conjunctival mucins, Invest Ophthalmol Vis Sci, vol.37, pp.2559-2571, 1996.

M. Malakhov, L. Aschenbrenner, D. Smee, M. Wandersee, R. Sidwell et al., Sialidase Fusion Protein as a Novel Broad-Spectrum Inhibitor of Influenza Virus Infection, Antimicrobial Agents and Chemotherapy, vol.50, issue.4, pp.1470-1479, 2006.
DOI : 10.1128/AAC.50.4.1470-1479.2006

F. Paulsen, A. Thale, G. Kohla, R. Schauer, R. Rochels et al., Functional anatomy of human lacrimal duct epithelium, Anatomy and Embryology, vol.198, issue.1, pp.1-12, 1998.
DOI : 10.1007/s004290050160