Molecular characterization of a discrete hemoglobinopathy upon investigation for a lung hydatic cyst in an old Tunisian patient.

Abstract : We report the case of an old Tunisian patient hospitalized for a complicated hydatic cyst of the right lung. Primary laboratory investigation showed a microcytic hypochromic anemia with an abnormal hemoglobin pattern. Hemoglobin analysis and DNA sequencing of the β-globin gene revealed a compound heterozygote, HbO-Arab/cd 39 β°-thalassemia. This hemoglobinopathy was never diagnosed earlier. It spent undiagnosed until the patient presented with hydatic cyst. Coexistence of the two pathologies complicated the general state of the patient and led to a severe anemia. The patient has undergone a surgical therapy for the hydatic cyst and was advised to start a follow up for her hemoglobinopathy.
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Submitted on : Wednesday, July 6, 2011 - 2:04:25 PM
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Imen Moumni, Sadok Yalaoui, Najla Ghrairi, Agnies Hamzaoui, Amin Zoraï, et al.. Molecular characterization of a discrete hemoglobinopathy upon investigation for a lung hydatic cyst in an old Tunisian patient.. Annales de Biologie Clinique, John Libbey Eurotext, 2011, 69 (3), pp.353-6. ⟨10.1684/abc.2011.0582⟩. ⟨pasteur-00606416⟩

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