First serological investigation of peste-des-petits-ruminants and Rift Valley fever in Tunisia.

Emna Ayari-Fakhfakh 1 Abdeljelil Ghram 1 Ali Bouattour 1 Imen Larbi 1 Latifa Gribâa-Dridi 1 Olivier Kwiatek 2 Michèle Bouloy 3 Geneviève Libeau 2 Emmanuel Albina 2 Catherine Cêtre-Sossah 2
1 Institut Pasteur de Tunis
2 UPR 15 Contrôle des maladies - Contrôle des maladies animales exotiques et émergentes
3 Génétique Moléculaire des Bunyavirus
Abstract : This study, carried out between September 2006 and January 2007, is the first cross-sectional serological investigation of peste-des-petits-ruminants (PPR) and Rift Valley fever (RVF) in Tunisia. The objective was to assess the potential need to develop a dual, recombinant PPR-RVF vaccine and how such a vaccine might be utilised in Tunisia. An overall PPR seroprevalence of 7.45% was determined, a finding supported by the high specificity (99.4%) and sensitivity (94.5%) of the ELISA used. On assessment of the diversity and density of mosquitoes in the sampling area, four species of RVF-vectors of the genus Aedes and Culex were identified. However, no serological evidence of RVF was found despite the use of a highly sensitive ELISA (99-100%). Larger scale investigations are underway to confirm these findings and the continuation of the emergency vaccination program against these two diseases remains valid.
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Submitted on : Thursday, July 7, 2011 - 10:35:39 AM
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CIRAD | PASTEUR | RIIP | RIIP_TUNIS | LISE | SORBONNE-UNIVERSITE | SU-SCIENCES

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Emna Ayari-Fakhfakh, Abdeljelil Ghram, Ali Bouattour, Imen Larbi, Latifa Gribâa-Dridi, et al.. First serological investigation of peste-des-petits-ruminants and Rift Valley fever in Tunisia.. Veterinary Journal, Elsevier, 2011, 187 (3), pp.402-4. ⟨10.1016/j.tvjl.2010.01.007⟩. ⟨pasteur-00606752⟩

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