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Determination of natural versus laboratory human infection with Mayaro virus by molecular analysis.

Abstract : A laboratory worker developed clinical signs of infection with Mayaro virus (Togaviridae), an arbovirus of South and Central America, 6 days after preparation of Mayaro viral antigen and 10 days after a trip to a rain forest. There was no evidence of skin lesions during the antigen preparation, and level 3 containment safety measures were followed. Therefore, molecular characterization of the virus was undertaken to identify the source of infection. RT-PCR and DNA sequence comparisons proved the infection was with the laboratory strain. Airborne Mayaro virus contamination is thus a hazard to laboratory personnel.
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Submitted on : Monday, July 11, 2011 - 5:08:29 PM
Last modification on : Tuesday, June 15, 2021 - 4:46:01 PM
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Tobias Junt, Jean-Michel Heraud, J. Lelarge, B. Labeau, Antoine Talarmin. Determination of natural versus laboratory human infection with Mayaro virus by molecular analysis.. Epidemiology and Infection, 1999, 123 (3), pp.511-513. ⟨10.1017/s0950268899003180⟩. ⟨pasteur-00607927⟩

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