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Journal articles
Age- Matched Comparison of Children Hospitalized for 2009 Pandemic H1N1 Influenza with Those Hospitalized for Seasonal H1N1 and H3N2.
Abstract : BACKGROUND: A wide spectrum of clinical manifestation ranging from deaths to a mild course of disease has been reported in children infected with the 2009 pandemic H1N1 (pH1N1) influenza. METHODOLOGY/MAJOR FINDINGS: We conducted an age-matched control study comparing children hospitalized for pH1N1 with historic controls infected with seasonal H1N1 and H3N2 influenza to correct for the effect of age on disease susceptibility and clinical manifestations. We also compared children with pH1N1 to children concurrently admitted for seasonal influenza during the pandemic period to adjust for differences in health-seeking behavior during the pandemic or other potential bias associated with historic controls. There was no death or intensive care admission. Children with pH1N1 were more likely to have at least one risk condition for influenza, an underlying chronic pulmonary condition, more likely to have asthma exacerbation and to be treated with oseltamivir. There was no difference in other aspects of the clinical course or outcome. CONCLUSION: Disease manifestation of children hospitalized for pH1N1 infection was mild in our patient population.
Cited literature [24 references]
https://hal-riip.archives-ouvertes.fr/pasteur-00614345
Contributor : Francois Kien Connect in order to contact the contributor
Submitted on : Thursday, August 11, 2011 - 5:33:05 PM
Last modification on : Thursday, July 11, 2019 - 2:10:06 PM
Long-term archiving on: : Saturday, November 12, 2011 - 2:20:55 AM
Contributor : Francois Kien Connect in order to contact the contributor
Submitted on : Thursday, August 11, 2011 - 5:33:05 PM
Last modification on : Thursday, July 11, 2019 - 2:10:06 PM
Long-term archiving on: : Saturday, November 12, 2011 - 2:20:55 AM
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journal.pone.0021837.pdf
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