Age- Matched Comparison of Children Hospitalized for 2009 Pandemic H1N1 Influenza with Those Hospitalized for Seasonal H1N1 and H3N2. - Archive ouverte HAL Access content directly
Journal Articles PLoS ONE Year : 2011

Age- Matched Comparison of Children Hospitalized for 2009 Pandemic H1N1 Influenza with Those Hospitalized for Seasonal H1N1 and H3N2.

(1) , (2) , (1) , (1) , (2, 3)
1
2
3

Abstract

BACKGROUND: A wide spectrum of clinical manifestation ranging from deaths to a mild course of disease has been reported in children infected with the 2009 pandemic H1N1 (pH1N1) influenza. METHODOLOGY/MAJOR FINDINGS: We conducted an age-matched control study comparing children hospitalized for pH1N1 with historic controls infected with seasonal H1N1 and H3N2 influenza to correct for the effect of age on disease susceptibility and clinical manifestations. We also compared children with pH1N1 to children concurrently admitted for seasonal influenza during the pandemic period to adjust for differences in health-seeking behavior during the pandemic or other potential bias associated with historic controls. There was no death or intensive care admission. Children with pH1N1 were more likely to have at least one risk condition for influenza, an underlying chronic pulmonary condition, more likely to have asthma exacerbation and to be treated with oseltamivir. There was no difference in other aspects of the clinical course or outcome. CONCLUSION: Disease manifestation of children hospitalized for pH1N1 infection was mild in our patient population.
Fichier principal
Vignette du fichier
journal.pone.0021837.pdf (83.97 Ko) Télécharger le fichier
Origin : Publisher files allowed on an open archive
Loading...

Dates and versions

pasteur-00614345 , version 1 (11-08-2011)

Identifiers

Cite

Susan S. Chiu, Kwok-Hung Chan, Wilfred H. S. Wong, Eunice L. Y. Chan, J. S. M. Peiris. Age- Matched Comparison of Children Hospitalized for 2009 Pandemic H1N1 Influenza with Those Hospitalized for Seasonal H1N1 and H3N2.. PLoS ONE, 2011, 6 (7), pp.e21837. ⟨10.1371/journal.pone.0021837⟩. ⟨pasteur-00614345⟩

Collections

RIIP RIIP_HONGKONG
40 View
206 Download

Altmetric

Share

Gmail Facebook Twitter LinkedIn More