Identification of an RNA Hairpin in Poliovirus RNA That Serves as the Primary Template in the In Vitro Uridylylation of VPg, Journal of Virology, vol.74, issue.22, pp.74-10359, 2000. ,
DOI : 10.1128/JVI.74.22.10359-10370.2000
Molecular epidemiology and evolution of enterovirus 71 strains isolated from, J. Virol, pp.73-9969, 1970. ,
Molecular Epidemiology of Human Enterovirus 71 Strains and Recent Outbreaks in the Asia-Pacific Region: Comparative Analysis of the VP1 and VP4 Genes, Emerging Infectious Diseases, vol.9, issue.4, pp.461-468, 2003. ,
DOI : 10.3201/eid0904.020395
Phylogenetic analysis of enterovirus 71 strains isolated during linked epidemics in Malaysia, J. Virol, pp.75-7732, 2001. ,
Epidemiologic and virologic investigation of hand, foot, and mouth disease, southern Vietnam, Emerg. Infect. Dis, vol.13, pp.1733-1741, 2005. ,
Frequent importation of enterovirus 71 from surrounding countries into the local community of Yamagata, J. Clin. Microbiol, pp.43-6171, 1998. ,
An overview of the evolution of enterovirus 71 and its clinical and public health significance, FEMS Microbiology Reviews, vol.26, issue.1, pp.91-107, 2002. ,
DOI : 10.1111/j.1574-6976.2002.tb00601.x
Molecular detection of enteroviruses from an outbreak of hand, foot and mouth disease in Malaysia in 1997, Scand, J. Infect. Dis, pp.31-331, 1999. ,
An Epidemic of Enterovirus 71 Infection in Taiwan, New England Journal of Medicine, vol.341, issue.13, pp.341-929, 1999. ,
DOI : 10.1056/NEJM199909233411301
Incidence and case-fatality rates resulting from the 1998 enterovirus 71 outbreak in Taiwan, Journal of Medical Virology, vol.5, issue.2, pp.67-217, 2002. ,
DOI : 10.1002/jmv.2210
Enterovirus 71 in Taiwan, Pediatrics & Neonatology, vol.49, issue.4, pp.103-112, 2008. ,
DOI : 10.1016/S1875-9572(08)60023-6
Neurologic Complications in Children with Enterovirus 71 Infection, New England Journal of Medicine, vol.341, issue.13, pp.341-936, 1999. ,
DOI : 10.1056/NEJM199909233411302
Outbreak of severe neurologic involvement associated with enterovirus 71 infection, Pediatric Neurology, vol.20, issue.1, pp.17-23, 1999. ,
DOI : 10.1016/S0887-8994(98)00087-3
Fatal enterovirus 71 encephalomyelitis, The Journal of Pediatrics, vol.133, issue.6, pp.133-795, 1998. ,
DOI : 10.1016/S0022-3476(98)70155-6
Clinical Spectrum of Enterovirus 71 Infection in Children in Southern Taiwan, with an Emphasis on Neurological Complications, Clinical Infectious Diseases, vol.29, issue.1, pp.29-184, 1999. ,
DOI : 10.1086/520149
Advances in the study of enterovirus 71 infection, J. Pathogen Biol, vol.3, pp.947-949, 2008. ,
Enterovirus 71 outbreak in the People's Republic of China, J. Clin. Microbiol, pp.47-2351, 2008. ,
An outbreak of hand, foot, and mouth disease associated with subgenotype C4 of human enterovirus 71 in Shandong, China, Journal of Clinical Virology, vol.44, issue.4, pp.44-262, 2009. ,
DOI : 10.1016/j.jcv.2009.02.002
Design, synthesis, and structure???activity relationships of pyrazolo[3,4-d]pyrimidines: a novel class of potent enterovirus inhibitors, Bioorganic & Medicinal Chemistry Letters, vol.14, issue.10, pp.2519-2525, 2004. ,
DOI : 10.1016/j.bmcl.2004.02.092
Novel Antiviral Agent DTriP-22 Targets RNA-Dependent RNA Polymerase of Enterovirus 71, Antimicrobial Agents and Chemotherapy, vol.53, issue.7, pp.2740-2747, 2009. ,
DOI : 10.1128/AAC.00101-09
Structures of EV71 RNA-dependent RNA polymerase in complex with substrate and analogue provide a drug target against the hand-foot-and-mouth disease pandemic in China, Protein & Cell, vol.283, issue.5, pp.491-500, 2010. ,
DOI : 10.1007/s13238-010-0061-7
Genetic evolution of enterovirus 71: epidemiological and pathological implications, Reviews in Medical Virology, vol.12, issue.6, pp.371-379, 2007. ,
DOI : 10.1002/rmv.538
Temperature-sensitive mutants of enterovirus 71 show attenuation in cynomolgus monkeys, Journal of General Virology, vol.86, issue.5, pp.86-1391, 2005. ,
DOI : 10.1099/vir.0.80784-0
RNA Polymerase Activity and Specific RNA Structure Are Required for Efficient HCV Replication in Cultured Cells, PLoS Pathogens, vol.274, issue.12, p.1000885, 2010. ,
DOI : 10.1371/journal.ppat.1000885.s005
URL : https://hal.archives-ouvertes.fr/pasteur-00624881
Poliovirus RNA-dependent RNA polymerase (3D(pol)) Assembly of stable, elongation-competent complexes by using a symmetrical primer-template substrate (sym/sub, J. Biol. Chem, pp.275-5329, 2000. ,
Modification of hepatitis C virus 1b RNA polymerase to make a highly active JFH1-type polymerase by mutation of the thumb domain, Archives of Virology, vol.74, issue.5, pp.765-773, 2009. ,
DOI : 10.1007/s00705-009-0366-0
URL : https://hal.archives-ouvertes.fr/pasteur-00625244
Measurement of poliovirus RNA polymerase binding to poliovirion and nonviral RNAs using a filter-binding assay, Nucleic Acids Research, vol.16, issue.21, pp.10339-10352, 1988. ,
DOI : 10.1093/nar/16.21.10339
Influenza virus PB1 protein is the minimal and essential subunit of RNA polymerase, Archives of Virology, vol.88, issue.3-4, pp.525-539, 1996. ,
DOI : 10.1007/BF01718315
De Novo Initiation of RNA Synthesis by the RNA-Dependent RNA Polymerase (NS5B) of Hepatitis C Virus, Journal of Virology, vol.74, issue.2, pp.74-851, 2000. ,
DOI : 10.1128/JVI.74.2.851-863.2000
Poliovirus RNA-dependent RNA polymerase (3Dpol) is sufficient for template switching in vitro, J. Biol. Chem, pp.274-2706, 1999. ,
DNA Polymerases: Structural Diversity and Common Mechanisms, Journal of Biological Chemistry, vol.274, issue.25, pp.17395-17398, 1999. ,
DOI : 10.1074/jbc.274.25.17395
A comparison of viral RNA-dependent RNA polymerases, Current Opinion in Structural Biology, vol.16, issue.1, pp.27-34, 2006. ,
DOI : 10.1016/j.sbi.2005.12.002
Structural and functional insights provided by crystal structures of DNA polymerases and their substrate complexes, Current Opinion in Structural Biology, vol.8, issue.1, pp.54-63, 1998. ,
DOI : 10.1016/S0959-440X(98)80010-9
Determinants of RNA-Dependent RNA Polymerase (In)fidelity Revealed by Kinetic Analysis of the Polymerase Encoded by a Foot-and-Mouth Disease Virus Mutant with Reduced Sensitivity to Ribavirin, Journal of Virology, vol.82, issue.24, pp.82-12346, 2008. ,
DOI : 10.1128/JVI.01297-08
Biochemical characterization of rhinovirus RNA-dependent RNA polymerase, Antiviral Research, vol.56, issue.2, pp.99-114, 2002. ,
DOI : 10.1016/S0166-3542(02)00101-8
The Crystal Structure of Coxsackievirus B3 RNA-Dependent RNA Polymerase in Complex with Its Protein Primer VPg Confirms the Existence of a Second VPg Binding Site on Picornaviridae Polymerases, Journal of Virology, vol.82, issue.19, pp.9577-9590, 2008. ,
DOI : 10.1128/JVI.00631-08
Crystal Structure of Coxsackievirus B3 3Dpol Highlights the Functional Importance of Residue 5 in Picornavirus Polymerases, Journal of Virology, vol.82, issue.19, pp.9458-9464, 2008. ,
DOI : 10.1128/JVI.00647-08
Effect of manganese ions on the incorporation of dideoxynucleotides by bacteriophage T7 DNA polymerase and Escherichia coli DNA polymerase I., Proceedings of the National Academy of Sciences, vol.86, issue.11, pp.86-4076, 1989. ,
DOI : 10.1073/pnas.86.11.4076
Synthesis of complementary strands of heterologous RNAs with Qbeta replicase, Proc. Natl. Acad. Sci. U. S. A, pp.71-1371, 1974. ,
Regulation of magnesium homeostasis and transport in mammalian cells, Archives of Biochemistry and Biophysics, vol.458, issue.1, pp.90-102, 2007. ,
DOI : 10.1016/j.abb.2006.07.012
Sub-cellular localization of manganese in the basal ganglia of normal and manganese-treated rats, NeuroToxicology, vol.29, issue.1, pp.60-72, 2008. ,
DOI : 10.1016/j.neuro.2007.09.001
Manganese accumulates primarily in nuclei of cultured brain cells, NeuroToxicology, vol.29, issue.3, pp.466-470, 2008. ,
DOI : 10.1016/j.neuro.2008.02.012
Poliovirus RNAdependent RNA polymerase (3Dpol): structural, biochemical, and biological analysis of conserved structural motifs A and B, J. Biol. Chem, pp.275-25523, 2000. ,
Analysis of recombination and natural selection in human enterovirus 71, Virology, vol.398, issue.2, pp.251-261, 2010. ,
DOI : 10.1016/j.virol.2009.12.007
Appearance of mosaic enterovirus 71 in the 2008 outbreak of China, Virus Research, vol.145, issue.1, 2009. ,
DOI : 10.1016/j.virusres.2009.06.006
Appearance of intratypic recombination of enterovirus 71 in Taiwan from 2002 to 2005, Virus Research, vol.131, issue.2, pp.250-259, 2002. ,
DOI : 10.1016/j.virusres.2007.10.002
An emerging recombinant human enterovirus 71 responsible for the 2008 outbreak of Hand Foot and Mouth Disease in Fuyang city of China, An emerging recombinant human enterovirus 71 responsible for the 2008 outbreak of Hand Foot and Mouth Disease in Fuyang city of China, p.94, 2010. ,
DOI : 10.1186/1743-422X-7-94
Mutant Viral Polymerase in the Transition of Virus to Error Catastrophe Identifies a Critical Site for RNA Binding, Journal of Molecular Biology, vol.353, issue.5, pp.353-1021, 2005. ,
DOI : 10.1016/j.jmb.2005.09.022
Functional oligomerization of poliovirus RNAdependent RNA polymerase, RNA, vol.1, pp.466-477, 1995. ,
MELTING, computing the melting temperature of nucleic acid duplex, Bioinformatics, vol.17, issue.12, pp.17-1226, 2001. ,
DOI : 10.1093/bioinformatics/17.12.1226
Identification of terminal adenylyl transferase activity of the poliovirus polymerase 3Dpol, J. Virol, pp.68-5811, 1994. ,
Structure of the RNA-dependent RNA polymerase of poliovirus, Structure, vol.5, issue.8, pp.1109-1122, 1997. ,
DOI : 10.1016/S0969-2126(97)00261-X
Site Size of Cooperative Single-stranded RNA Binding by Poliovirus RNA-dependent RNA Polymerase, Journal of Biological Chemistry, vol.273, issue.12, pp.6724-6730, 1998. ,
DOI : 10.1074/jbc.273.12.6724
Biochemical and kinetic analysis of the influenza virus RNA polymerase purified from insect cells, Biochemical and Biophysical Research Communications, vol.391, issue.1, pp.391-570, 2010. ,
DOI : 10.1016/j.bbrc.2009.11.100
URL : https://hal.archives-ouvertes.fr/pasteur-00624863
Poliovirus RNA-dependent RNA polymerase (3D(pol)). Divalent cation modulation of primer, template, and nucleotide selection, J. Biol. Chem, pp.274-37060, 1999. ,
Ribavirin Reduces Mortality in Enterovirus 71???Infected Mice by Decreasing Viral Replication, The Journal of Infectious Diseases, vol.197, issue.6, pp.854-857, 2008. ,
DOI : 10.1086/527326
Studies with poliovirus polymerase 3Dpol. Stimulation of poly(U) synthesis in vitro by purified poliovirus protein 3AB, J. Biol. Chem, pp.269-29173, 1994. ,