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Epidemiologic and clinical features of cutaneous leishmaniasis in southeastern Tunisia.

Abstract : Species-specific diagnosis was performed in 66 patients with cutaneous leishmaniasis (CL) living in Tataouine focus in southeastern Tunisia. Leishmania DNA was extracted directly from dermal scrapings (n = 66) and from parasites obtained in culture (n = 12). Species were identified by using polymerase chain reaction-restriction fragment length polymorphism analysis for internal transcribed spacer region 1 and isoenzyme analysis. Leishmania tropica and L. major were identified in 31 (47%) and 35 (53%) cases respectively. Leishmania tropica CL cases were geographically scattered, and L. major CL cases were clustered. Lesions caused by L. tropica were mostly single (83.8%) and face-localized (55.8%), and lesions caused by L. major were multiple (57.1%; P < 0.001) and situated on limbs (83.7%; P < 0.001). For both species, most lesion onsets were reported during June-January. However, lesions that emerged during February-May were mainly caused by L. tropica (83.3%; P < 0.01). Moreover, the delay before seeking medical advice was higher for L. tropica infections than for L. major infections (P < 0.05).
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Submitted on : Friday, September 23, 2011 - 6:22:30 PM
Last modification on : Monday, October 8, 2018 - 5:44:04 PM

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Nadia Bousslimi, Karim Aoun, Imène Ben-Abda, Nissaf Ben-Alaya-Bouafif, Mohamed Raouane, et al.. Epidemiologic and clinical features of cutaneous leishmaniasis in southeastern Tunisia.. American Journal of Tropical Medicine and Hygiene, 2010, 83 (5), pp.1034-9. ⟨10.4269/ajtmh.2010.10-0234⟩. ⟨pasteur-00620980⟩



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