Plasticity of CD4+ T Cell Lineage Differentiation, Immunity, vol.30, issue.5, pp.646-55, 2009. ,
DOI : 10.1016/j.immuni.2009.05.001
TGF-??-induced Foxp3 inhibits TH17 cell differentiation by antagonizing ROR??t function, Nature, vol.288, issue.7192, pp.236-276, 2008. ,
DOI : 10.1038/nature06878
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2597437
Preferential Generation of Follicular B Helper T Cells from Foxp3+ T Cells in Gut Peyer's Patches, Science, vol.323, issue.5920, pp.1488-92, 2009. ,
DOI : 10.1126/science.1169152
Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo, Nature Immunology, vol.34, issue.9, pp.1000-1007, 2009. ,
DOI : 10.1038/ni.1774
A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis, Nature, vol.389, pp.737-779, 1997. ,
Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis, Science, vol.265, issue.5176, pp.1237-1277, 1994. ,
DOI : 10.1126/science.7520605
Inhibition of follicular T-helper cells by CD8+ regulatory T cells is essential for self tolerance, Nature, vol.62, issue.7313, pp.328-360, 2010. ,
DOI : 10.1038/nature09370
Long-Term Clinical Efficacy of Grass-Pollen Immunotherapy, New England Journal of Medicine, vol.341, issue.7, pp.468-75, 1999. ,
DOI : 10.1056/NEJM199908123410702
IL-10 and TGF-?? cooperate in the regulatory T cell response to mucosal allergens in normal immunity and specific immunotherapy, European Journal of Immunology, vol.33, issue.5, pp.1205-1219, 2003. ,
DOI : 10.1002/eji.200322919
Therapeutic approaches to allergy and autoimmunity based on FoxP3+ regulatory T-cell activation and expansion, Journal of Allergy and Clinical Immunology, vol.123, issue.4, pp.749-55, 2009. ,
DOI : 10.1016/j.jaci.2009.03.001
Anti-CD3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice., Proceedings of the National Academy of Sciences, vol.91, issue.1, pp.123-130, 1994. ,
DOI : 10.1073/pnas.91.1.123
Treatment with Nonmitogenic Anti-CD3 Monoclonal Antibody Induces CD4+ T Cell Unresponsiveness and Functional Reversal of Established Experimental Autoimmune Encephalomyelitis, The Journal of Immunology, vol.174, issue.8, pp.4525-4559, 2005. ,
DOI : 10.4049/jimmunol.174.8.4525
T cells, Immunology, vol.171, issue.4, pp.479-87, 2006. ,
DOI : 10.1016/0008-8749(90)90032-M
URL : https://hal.archives-ouvertes.fr/inserm-01214610
High and Low Vitamin A Therapies Induce Distinct FoxP3+ T-Cell Subsets and Effectively Control Intestinal Inflammation, Gastroenterology, vol.137, issue.4, pp.1391-402, 2009. ,
DOI : 10.1053/j.gastro.2009.06.063
Normalization of obesity-associated insulin resistance through immunotherapy, Nature Medicine, vol.56, issue.8, pp.921-930, 2009. ,
DOI : 10.1038/nm.2001
Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters, Nature Medicine, vol.38, issue.8, pp.930-939, 2009. ,
DOI : 10.1038/nm.2002
Influence of neoadjuvant radio-chemotherapy on tumor-infiltrating lymphocytes in squamous esophageal cancer, European Journal of Surgical Oncology (EJSO), vol.35, issue.12, pp.1268-72, 2009. ,
DOI : 10.1016/j.ejso.2009.07.002
A brief history of TH17, the first major revision in the TH1/TH2 hypothesis of T cell???mediated tissue damage, Nature Medicine, vol.59, issue.2, pp.139-184, 2007. ,
DOI : 10.1038/nm1551
Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17, Journal of Leukocyte Biology, vol.81, issue.5, pp.1258-68, 2007. ,
DOI : 10.1189/jlb.1006610
IL-17 and Th17 Cells, Annual Review of Immunology, vol.27, issue.1, pp.485-517, 2009. ,
DOI : 10.1146/annurev.immunol.021908.132710
IL-17 Plays an Important Role in the Development of Experimental Autoimmune Encephalomyelitis, The Journal of Immunology, vol.177, issue.1, pp.566-73, 2006. ,
DOI : 10.4049/jimmunol.177.1.566
Interleukin-17 is a potent immuno-modulator and regulator of normal human intestinal epithelial cell growth, Biochemical and Biophysical Research Communications, vol.337, issue.2, pp.505-514, 2005. ,
DOI : 10.1016/j.bbrc.2005.09.075
TH1 and TH2 Cells: Different Patterns of Lymphokine Secretion Lead to Different Functional Properties, Annual Review of Immunology, vol.7, issue.1, pp.145-73, 1989. ,
DOI : 10.1146/annurev.iy.07.040189.001045
Novel p19 Protein Engages IL-12p40 to Form a Cytokine, IL-23, with Biological Activities Similar as Well as Distinct from IL-12, Immunity, vol.13, issue.5, pp.715-740, 2000. ,
DOI : 10.1016/S1074-7613(00)00070-4
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17, Nature Immunology, vol.103, issue.11, pp.1133-1174, 2005. ,
DOI : 10.1038/35051100
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation, The Journal of Experimental Medicine, vol.71, issue.2, pp.233-273, 2005. ,
DOI : 10.1038/nri802
Interleukin-23 Promotes a Distinct CD4 T Cell Activation State Characterized by the Production of Interleukin-17, Journal of Biological Chemistry, vol.278, issue.3, pp.1910-1914, 2003. ,
DOI : 10.1074/jbc.M207577200
IL-12p35-Deficient Mice Are Susceptible to Experimental Autoimmune Encephalomyelitis: Evidence for Redundancy in the IL-12 System in the Induction of Central Nervous System Autoimmune Demyelination, The Journal of Immunology, vol.169, issue.12, pp.7104-7114, 2002. ,
DOI : 10.4049/jimmunol.169.12.7104
A protective function for interleukin 17A in T cell-mediated intestinal inflammation, Nat Immunol, vol.10, pp.603-612, 2009. ,
Identification of IL-17-producing FOXP3+ regulatory T cells in humans, Proceedings of the National Academy of Sciences, vol.106, issue.12, pp.4793-4801, 2009. ,
DOI : 10.1073/pnas.0900408106
Foxp3 occupancy and regulation of key target genes during T-cell stimulation, Nature, vol.37, issue.7130, pp.931-936, 2007. ,
DOI : 10.1038/nature05478
IL-2 Is Essential for TGF-?? to Convert Naive CD4+CD25- Cells to CD25+Foxp3+ Regulatory T Cells and for Expansion of These Cells, The Journal of Immunology, vol.178, issue.4, pp.2018-2045, 2007. ,
DOI : 10.4049/jimmunol.178.4.2018
Regulatory T Cells and Immune Tolerance, Cell, vol.133, issue.5, pp.775-87, 2008. ,
DOI : 10.1016/j.cell.2008.05.009
FOXP3 is a homo-oligomer and a component of a supramolecular regulatory complex disabled in the human XLAAD/IPEX autoimmune disease, International Immunology, vol.19, issue.7, pp.825-860, 2007. ,
DOI : 10.1093/intimm/dxm043
FOXP3 Controls Regulatory T Cell Function through Cooperation with NFAT, Cell, vol.126, issue.2, pp.375-87, 2006. ,
DOI : 10.1016/j.cell.2006.05.042
URL : http://doi.org/10.1016/j.cell.2006.05.042
Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1, Nature, vol.35, issue.7136, pp.685-694, 2007. ,
DOI : 10.1038/nature05673
Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses, Nature, vol.32, issue.7236, pp.351-357, 2009. ,
DOI : 10.1038/nature07674
CD4+ Regulatory T Cells Control TH17 Responses in a Stat3-Dependent Manner, Science, vol.326, issue.5955, pp.986-91, 2009. ,
DOI : 10.1126/science.1172702
FoxP3 maintains Treg unresponsiveness by selectively inhibiting the promoter DNA-binding activity of AP-1, Blood, vol.111, issue.7, pp.3599-606, 2008. ,
DOI : 10.1182/blood-2007-09-115014
Eos Mediates Foxp3-Dependent Gene Silencing in CD4+ Regulatory T Cells, Science, vol.325, issue.5944, pp.1142-1148, 2009. ,
DOI : 10.1126/science.1176077
Foxp3 interacts with nuclear factor of activated T cells and NF-??B to repress cytokine gene expression and effector functions of T helper cells, Proceedings of the National Academy of Sciences, vol.102, issue.14, pp.5138-5181, 2005. ,
DOI : 10.1073/pnas.0501675102
FOXP3 interactions with histone acetyltransferase and class II histone deacetylases are required for repression, Proceedings of the National Academy of Sciences, vol.104, issue.11, pp.4571-4577, 2007. ,
DOI : 10.1073/pnas.0700298104
Interactions among the transcription factors Runx1, ROR??t and Foxp3 regulate the differentiation of interleukin 17???producing T cells, Nature Immunology, vol.203, issue.11, pp.1297-306, 2008. ,
DOI : 10.1038/ni.1663
FOXP3 Actively Represses Transcription by Recruiting the HAT/HDAC Complex, Cell Cycle, vol.6, issue.12, pp.1432-1438, 2007. ,
DOI : 10.4161/cc.6.12.4421
Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate, Nature, vol.204, issue.7282, pp.808-820, 2010. ,
DOI : 10.1038/nature08750
Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity, The Journal of Experimental Medicine, vol.27, issue.9, pp.1983-91, 2008. ,
DOI : 10.1006/geno.2000.6451
Foxp3-Dependent MicroRNA155 Confers Competitive Fitness to Regulatory T Cells by Targeting SOCS1 Protein, Immunity, vol.30, issue.1, pp.80-91, 2009. ,
DOI : 10.1016/j.immuni.2008.11.010
URL : http://doi.org/10.1016/j.immuni.2008.11.010
Function of miR-146a in Controlling Treg Cell-Mediated Regulation of Th1 Responses, Cell, vol.142, issue.6, pp.914-943, 2010. ,
DOI : 10.1016/j.cell.2010.08.012
The transcription cofactor Hopx is required for regulatory T cell function in dendritic cell???mediated peripheral T cell unresponsiveness, Nature Immunology, vol.141, issue.10, pp.962-970, 2010. ,
DOI : 10.1016/0092-8674(88)90244-9
The Orphan Nuclear Receptor ROR??t Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells, Cell, vol.126, issue.6, pp.1121-1154, 2006. ,
DOI : 10.1016/j.cell.2006.07.035
T Helper 17 Lineage Differentiation Is Programmed by Orphan Nuclear Receptors ROR?? and ROR??, Immunity, vol.28, issue.1, pp.29-39, 2008. ,
DOI : 10.1016/j.immuni.2007.11.016
URL : http://doi.org/10.1016/j.immuni.2007.11.016
STAT3 Regulates Cytokine-mediated Generation of Inflammatory Helper T Cells, Journal of Biological Chemistry, vol.282, issue.13, pp.9358-63, 2007. ,
DOI : 10.1074/jbc.C600321200
The development of inflammatory TH-17 cells requires interferon-regulatory factor 4, Nature Immunology, vol.163, issue.9, pp.958-66, 2007. ,
DOI : 10.1016/j.jneuroim.2006.06.026
Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor, Nature, vol.101, issue.7191, pp.65-71, 2008. ,
DOI : 10.1038/nature06880
Transcriptional regulation of Th17 cell differentiation, Seminars in Immunology, vol.19, issue.6, pp.409-426, 2007. ,
DOI : 10.1016/j.smim.2007.10.011
Foxp3 Inhibits ROR??t-mediated IL-17A mRNA Transcription through Direct Interaction with ROR??t, Journal of Biological Chemistry, vol.283, issue.25, pp.17003-17011, 2008. ,
DOI : 10.1074/jbc.M801286200
The genetics and epigenetics of autoimmune diseases, Journal of Autoimmunity, vol.33, issue.1, pp.3-11, 2009. ,
DOI : 10.1016/j.jaut.2009.03.007
Cutting Edge: TCR Stimulation Is Sufficient for Induction of Foxp3 Expression in the Absence of DNA Methyltransferase 1, The Journal of Immunology, vol.182, issue.11, pp.6648-52, 2009. ,
DOI : 10.4049/jimmunol.0803320
A voxel-based morphometry comparison of regional gray matter between fragile X syndrome and autism, Psychiatry Research: Neuroimaging, vol.174, issue.2, pp.138-183, 2009. ,
DOI : 10.1016/j.pscychresns.2009.04.013
Reversible Histone Acetylation and Deacetylation Mediate Genome-Wide, Promoter-Dependent and Locus-Specific Changes in Gene Expression During Plant Development, Genetics, vol.169, issue.1, pp.337-382, 2005. ,
DOI : 10.1534/genetics.104.033142
Deacetylase inhibition promotes the generation and function of regulatory T cells, Nature Medicine, vol.90, issue.11, pp.1299-307, 2007. ,
DOI : 10.1038/nm1652
Epigenetic control of FOXP3 expression: the key to a stable regulatory T-cell lineage?, Nature Reviews Immunology, vol.105, issue.2, pp.83-92, 2009. ,
DOI : 10.1038/nri2474
Epigenetic Control of the foxp3 Locus in Regulatory T Cells, PLoS Biology, vol.31, issue.2, p.38, 2007. ,
DOI : 10.1371/journal.pbio.0050038.st001
Epigenetic inheritance of DNA methylation limits activation-induced expression Z, International Immunopharmacology, vol.11, pp.536-542, 2011. ,
DNA methylation controls Foxp3 gene expression, European Journal of Immunology, vol.175, issue.6, pp.1654-63, 2008. ,
DOI : 10.1002/eji.200838105
Stability of the Regulatory T Cell Lineage in Vivo, Science, vol.329, issue.5999, pp.1667-71, 2010. ,
DOI : 10.1126/science.1191996
The receptor S1P1 overrides regulatory T cell???mediated immune suppression through Akt-mTOR, Nature Immunology, vol.8, issue.7 ,
DOI : 10.1038/ni.1743
The S1P1-mTOR axis directs the reciprocal differentiation of TH1 and Treg cells, Nature Immunology, vol.178, issue.11, pp.1047-56, 2010. ,
DOI : 10.1091/mbc.E05-09-0853
Molecular Antagonism and Plasticity of Regulatory and Inflammatory T Cell Programs, Immunity, vol.29, issue.1, pp.44-56, 2008. ,
DOI : 10.1016/j.immuni.2008.05.007
Global Mapping of H3K4me3 and H3K27me3 Reveals Specificity and Plasticity in Lineage Fate Determination of Differentiating CD4+ T Cells, Immunity, vol.30, issue.1, pp.155-67, 2009. ,
DOI : 10.1016/j.immuni.2008.12.009
Generation of pathogenic TH17 cells in the absence of TGF-?? signalling, Nature, vol.282, issue.7318, pp.967-71, 2010. ,
DOI : 10.1038/nature09447