[Microsporidia and cryptosporidia coinfection in an HIV-infected newborn.]

R. Abdelmalek 1, 2 S. Anane 2 N. Chabchoub 1 R. Essid 1 K. Aoun 3 T Ben Chaabéne 2 A. Bouratbine 3
1 LR 05-SP 03 - Laboratoire des parasitoses émergentes, Institut Pasteur de Tunis
2 Hôpital La Rabta [Tunis]
3 Laboratoire de Parasitologie, Institut Pasteur de Tunis
Abstract : Microsporidiosis and cryptosporidiosis are emerging opportunistic infections responsible for intestinal manifestations that are often severe in immunocompromised patients. A case of microsporidiosis-cryptosporidiosis coinfection is reported in an HIV-infected newborn. The patient was a 17-day-old female, exclusively breastfed and with no contact with animals. Microsporidiosis and cryptosporidiosis were diagnosed after systematic screening in stool samples using both specific staining and PCR. Two species of microsporidia, Encephalitozoon intestinalis and Enterocytozoon bieneusi, and Cryptosporidium hominis were identified. The contamination of the newborn probably resulted from direct human-to-human transmission during close contact with the mother (who had diarrhea and refused stool sampling). This report highlights the usefulness of the screening of intestinal microsporidiosis and cryptosporidiosis in HIV-infected subjects for better management.
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Journal articles
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Submitted on : Friday, January 20, 2012 - 11:40:41 AM
Last modification on : Tuesday, April 23, 2019 - 3:04:02 PM

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R. Abdelmalek, S. Anane, N. Chabchoub, R. Essid, K. Aoun, et al.. [Microsporidia and cryptosporidia coinfection in an HIV-infected newborn.]. Archives de Pédiatrie, Elsevier, 2011, epub ahead of print. ⟨10.1016/j.arcped.2011.02.016⟩. ⟨pasteur-00661651⟩

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