Species-specific interactions of Src family tyrosine kinases regulate Chlamydia intracellular growth and trafficking.

Cherilyn A Elwell (1, 2) , Arlinet Kierbel (3) , Joanne N Engel (1, 2, 4)

1 Medicine department
2 Institut Pasteur de Montevideo
3 Microbial Pathogenesis and Host Defense Program
4 Microbiology and Immunology

Src family kinases (SFKs) regulate key cellular processes and are emerging as important targets for intracellular pathogens. In this commentary, we briefly review the role of SFKs in bacterial pathogenesis and highlight new work on the role of SFKs during the intracellular cycle of Chlamydia species.

Domaines: Biologie cellulaire; Microbiologie et Parasitologie

Cherilyn A Elwell, Arlinet Kierbel, Joanne N Engel. Species-specific interactions of Src family tyrosine kinases regulate Chlamydia intracellular growth and trafficking.. mBio, 2011, 2 (3), pp.e00082-11. ⟨10.1128/mBio.00082-11⟩. ⟨pasteur-00685238⟩