Finer snapshot of circulating Mycobacterium tuberculosis genotypes in Guadeloupe, Martinique, and French Guiana.

Julie Millet (1) , William Laurent (1) , Thierry Zozio (1) , Nalin Rastogi (1)

1 Institut Pasteur de la Guadeloupe

This study shows the benefit of spoligotyping coupled to mycobacterial interspersed repetitive-unit (MIRU) typing to pinpoint circulating Mycobacterium tuberculosis genotypes in Guadeloupe, Martinique, and French Guiana. We hereby propose reduced 4-locus and 6-locus subsets for LAM and Haarlem lineage strains that predominate in South America and the Caribbean, retaining 99.35% and 99.64% of the total discriminatory power of the 12-locus scheme, respectively.

Domaines: Bactériologie

Julie Millet, William Laurent, Thierry Zozio, Nalin Rastogi. Finer snapshot of circulating Mycobacterium tuberculosis genotypes in Guadeloupe, Martinique, and French Guiana.. Journal of Clinical Microbiology, 2011, 49 (7), pp.2685-7. ⟨10.1128/JCM.00708-11⟩. ⟨pasteur-00691760⟩