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Generic microtiter plate assay for triaging clinical specimens prior to genotyping of human papillomavirus DNA via consensus PCR.

Abstract : A generic human papillomavirus (HPV) probe assay was compared to the Linear Array to detect HPV DNA in 1,013 clinical specimens. The sensitivity, specificity, and negative predictive value of the assay were 99.5% (95% confidence interval [CI], 98.4% to 99.9%), 58.6% (95% CI, 53.9% to 63.1%), and 98.9% (95% CI, 96.5% to 99.8%), respectively. This assay conveniently identifies HPV-positive specimens.
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Submitted on : Thursday, August 2, 2012 - 8:14:23 PM
Last modification on : Monday, July 20, 2020 - 12:33:14 PM

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Véronique Legault, Ann Burchell, Patricia Goggin, Belinda Nicolau, Paul Brassard, et al.. Generic microtiter plate assay for triaging clinical specimens prior to genotyping of human papillomavirus DNA via consensus PCR.. Journal of Clinical Microbiology, American Society for Microbiology, 2011, 49 (11), pp.3977-9. ⟨10.1128/JCM.05646-11⟩. ⟨pasteur-00722655⟩

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