D. Chaussabel, R. Semnani, M. Mcdowell, D. Sacks, and A. Sher, Unique gene expression profiles of human macrophages and dendritic cells to phylogenetically distinct parasites, Blood, vol.102, issue.2, pp.672-681, 2003.
DOI : 10.1182/blood-2002-10-3232

S. Buates and G. Matlashewski, General Suppression of Macrophage Gene Expression During Leishmania donovani Infection, The Journal of Immunology, vol.166, issue.5, pp.3416-3422, 2001.
DOI : 10.4049/jimmunol.166.5.3416

N. Rodriguez, H. Chang, and M. Wilson, Novel Program of Macrophage Gene Expression Induced by Phagocytosis of Leishmania chagasi, Infection and Immunity, vol.72, issue.4, pp.2111-2122, 2004.
DOI : 10.1128/IAI.72.4.2111-2122.2004

J. Osorio-y-fortea, E. De-la-llave, B. Regnault, J. Coppee, and G. Milon, Transcriptional signatures of BALB/c mouse macrophages housing multiplying Leishmania amazonensis amastigotes, BMC Genomics, vol.10, issue.1, p.119, 2009.
DOI : 10.1186/1471-2164-10-119

URL : https://hal.archives-ouvertes.fr/pasteur-00376739

R. Gentleman, V. Carey, D. Bates, B. Bolstad, and M. Dettling, Bioconductor: open software development for computational biology and bioinformatics, Genome Biology, vol.5, issue.10, p.80, 2004.
DOI : 10.1186/gb-2004-5-10-r80

M. Dai, P. Wang, A. Boyd, G. Kostov, and B. Athey, Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data, Nucleic Acids Research, vol.33, issue.20, p.175, 2005.
DOI : 10.1093/nar/gni179

A. Kasprzyk, D. Keefe, D. Smedley, D. London, and W. Spooner, EnsMart: A Generic System for Fast and Flexible Access to Biological Data, Genome Research, vol.14, issue.1, pp.160-169, 2004.
DOI : 10.1101/gr.1645104

S. Durinck, Y. Moreau, A. Kasprzyk, S. Davis, D. Moor et al., BioMart and Bioconductor: a powerful link between biological databases and microarray data analysis, Bioinformatics, vol.21, issue.16, pp.3439-3440, 2005.
DOI : 10.1093/bioinformatics/bti525

E. Birney, D. Andrews, M. Caccamo, Y. Chen, and L. Clarke, Ensembl 2006, Nucleic Acids Research, vol.34, issue.90001, pp.556-561, 2006.
DOI : 10.1093/nar/gkj133

K. Kapur, Y. Xing, Z. Ouyang, and W. Wong, Exon arrays provide accurate assessments of gene expression, Genome Biology, vol.8, issue.5, p.82, 2007.
DOI : 10.1186/gb-2007-8-5-r82

R. Irizarry, B. Hobbs, C. F. Beazer-barclay, Y. Antonellis, and K. , Exploration, normalization, and summaries of high density oligonucleotide array probe level data, Biostatistics, vol.4, issue.2, pp.249-264, 2003.
DOI : 10.1093/biostatistics/4.2.249

K. Livak and T. Schmittgen, Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2???????CT Method, Methods, vol.25, issue.4, pp.402-408, 2001.
DOI : 10.1006/meth.2001.1262

M. Grandl and G. Schmitz, Fluorescent high-content imaging allows the discrimination and quantitation of E-LDL-induced lipid droplets and Ox-LDLgenerated phospholipidosis in human macrophages, Cytometry A, vol.77, pp.231-242, 2010.

E. Blanchette-mackie, N. Dwyer, L. Amende, H. Kruth, and J. Butler, Type-C Niemann-Pick disease: low density lipoprotein uptake is associated with premature cholesterol accumulation in the Golgi complex and excessive cholesterol storage in lysosomes., Proceedings of the National Academy of Sciences, vol.85, issue.21, pp.8022-8026, 1988.
DOI : 10.1073/pnas.85.21.8022

A. Leventhal, W. Chen, A. Tall, and I. Tabas, Acid Sphingomyelinase-deficient Macrophages Have Defective Cholesterol Trafficking and Efflux, Journal of Biological Chemistry, vol.276, issue.48, pp.44976-44983, 2001.
DOI : 10.1074/jbc.M106455200

D. Vargas-inchaustegui, A. Hogg, G. Tulliano, A. Llanos-cuentas, and J. Arevalo, CXCL10 Production by Human Monocytes in Response to Leishmania braziliensis Infection, Infection and Immunity, vol.78, issue.1, pp.301-308, 2010.
DOI : 10.1128/IAI.00959-09

D. Gregory, R. Sladek, M. Olivier, and G. Matlashewski, Comparison of the Effects of Leishmania major or Leishmania donovani Infection on Macrophage Gene Expression, Infection and Immunity, vol.76, issue.3, pp.1186-1192, 2008.
DOI : 10.1128/IAI.01320-07

U. Ritter and H. Korner, Divergent expression of inflammatory dermal chemokines in cutaneous leishmaniasis*, Parasite Immunology, vol.166, issue.6, pp.295-301, 2002.
DOI : 10.1084/jem.192.2.205

I. Blader, I. Manger, and J. Boothroyd, Microarray Analysis Reveals Previously Unknown Changes in Toxoplasma gondii-infected Human Cells, Journal of Biological Chemistry, vol.276, issue.26, pp.24223-24231, 2001.
DOI : 10.1074/jbc.M100951200

W. Spear, D. Chan, I. Coppens, R. Johnson, and A. Giaccia, The host cell transcription factor hypoxia-inducible factor 1 is required for Toxoplasma gondii growth and survival at physiological oxygen levels, Cellular Microbiology, vol.95, issue.2, pp.339-352, 2006.
DOI : 10.1128/IAI.69.1.501-507.2001

W. Arrais-silva, V. Paffaro, J. Yamada, A. Giorgio, and S. , Expression of hypoxia-inducible factor-1?? in the cutaneous lesions of BALB/c mice infected with Leishmania amazonensis, Experimental and Molecular Pathology, vol.78, issue.1, pp.49-54, 2005.
DOI : 10.1016/j.yexmp.2004.09.002

J. Repa, S. Turley, J. Lobaccaro, J. Medina, and L. Li, Regulation of Absorption and ABC1-Mediated Efflux of Cholesterol by RXR Heterodimers, Science, vol.289, issue.5484, pp.1524-1529, 2000.
DOI : 10.1126/science.289.5484.1524

A. Venkateswaran, J. Repa, J. Lobaccaro, A. Bronson, and D. Mangelsdorf, Human White/Murine ABC8 mRNA Levels Are Highly Induced in Lipid-loaded Macrophages. A TRANSCRIPTIONAL ROLE FOR SPECIFIC OXYSTEROLS, Journal of Biological Chemistry, vol.275, issue.19, pp.14700-14707, 2000.
DOI : 10.1074/jbc.275.19.14700

Y. Wang, B. Kurdi-haidar, and J. Oram, LXR-mediated activation of macrophage stearoyl-CoA desaturase generates unsaturated fatty acids that destabilize ABCA1, The Journal of Lipid Research, vol.45, issue.5, pp.972-980, 2004.
DOI : 10.1194/jlr.M400011-JLR200

P. Goluszko and B. Nowicki, Membrane Cholesterol: a Crucial Molecule Affecting Interactions of Microbial Pathogens with Mammalian Cells, Infection and Immunity, vol.73, issue.12, pp.7791-7796, 2005.
DOI : 10.1128/IAI.73.12.7791-7796.2005

I. Coppens, A. Sinai, and K. Joiner, Exploits Host Low-Density Lipoprotein Receptor-Mediated Endocytosis for Cholesterol Acquisition, The Journal of Cell Biology, vol.263, issue.1, pp.167-180, 2000.
DOI : 10.1074/jbc.270.19.11574

T. Pucadyil, P. Tewary, R. Madhubala, and A. Chattopadhyay, Cholesterol is required for Leishmania donovani infection: implications in leishmaniasis, Molecular and Biochemical Parasitology, vol.133, issue.2, pp.145-152, 2004.
DOI : 10.1016/j.molbiopara.2003.10.002

P. Tewary, K. Veena, T. Pucadyil, A. Chattopadhyay, and R. Madhubala, The sterol-binding antibiotic nystatin inhibits entry of non-opsonized Leishmania donovani into macrophages, Biochemical and Biophysical Research Communications, vol.339, issue.2, pp.661-666, 2006.
DOI : 10.1016/j.bbrc.2005.11.062

R. Melo, D. Avila, H. Fabrino, D. Almeida, P. Bozza et al., Macrophage lipid body induction by Chagas disease in vivo: putative intracellular domains for eicosanoid formation during infection, Tissue and Cell, vol.35, issue.1, pp.59-67, 2003.
DOI : 10.1016/S0040-8166(02)00105-2

A. Charron and L. Sibley, Host cells: mobilizable lipid resources for the intracellular parasite Toxoplasma gondii, J Cell Sci, vol.115, pp.3049-3059, 2002.

L. Portugal, L. Fernandes, P. Pedroso, V. Santiago, H. Gazzinelli et al., Influence of low-density lipoprotein (LDL) receptor on lipid composition, inflammation and parasitism during Toxoplasma gondii infection, Microbes and Infection, vol.10, issue.3, pp.276-284, 2008.
DOI : 10.1016/j.micinf.2007.12.001

K. Jackson, N. Klonis, D. Ferguson, A. Adisa, and C. Dogovski, Food vacuole-associated lipid bodies and heterogeneous lipid environments in the malaria parasite, Plasmodium falciparum, Molecular Microbiology, vol.277, issue.1, pp.109-122, 2004.
DOI : 10.1111/j.1365-2958.2004.04284.x

J. Cocchiaro, Y. Kumar, E. Fischer, T. Hackstadt, and R. Valdivia, Cytoplasmic lipid droplets are translocated into the lumen of the Chlamydia trachomatis parasitophorous vacuole, Proceedings of the National Academy of Sciences, vol.105, issue.27, pp.9379-9384, 2008.
DOI : 10.1073/pnas.0712241105

L. Bougneres, J. Helft, S. Tiwari, P. Vargas, and B. Chang, A Role for Lipid Bodies in the Cross-presentation of Phagocytosed Antigens by MHC Class I in Dendritic Cells, Immunity, vol.31, issue.2, pp.232-244, 2009.
DOI : 10.1016/j.immuni.2009.06.022

E. Muraille, D. Trez, C. Brait, M. , D. Baetselier et al., Genetically Resistant Mice Lacking MyD88-Adapter Protein Display a High Susceptibility to Leishmania major Infection Associated with a Polarized Th2 Response, The Journal of Immunology, vol.170, issue.8, pp.4237-4241, 2003.
DOI : 10.4049/jimmunol.170.8.4237

P. Kropf, M. Freudenberg, M. Modolell, H. Price, and S. Herath, Toll-Like Receptor 4 Contributes to Efficient Control of Infection with the Protozoan Parasite Leishmania major, Infection and Immunity, vol.72, issue.4, pp.1920-1928, 2004.
DOI : 10.1128/IAI.72.4.1920-1928.2004

J. Flandin, F. Chano, and A. Descoteaux, RNA interference reveals a role for TLR2 and TLR3 in the recognition ofLeishmania donovani promastigotes by interferon?????-primed macrophages, European Journal of Immunology, vol.164, issue.2, pp.411-420, 2006.
DOI : 10.1002/eji.200535079

F. Mcgillicuddy, M. De-la-llera-moya, C. Hinkle, M. Joshi, and E. Chiquoine, Inflammation Impairs Reverse Cholesterol Transport In Vivo, Circulation, vol.119, issue.8, pp.1135-1145, 2009.
DOI : 10.1161/CIRCULATIONAHA.108.810721

A. Castrillo, S. Joseph, S. Vaidya, M. Haberland, and A. Fogelman, Crosstalk between LXR and Toll-like Receptor Signaling Mediates Bacterial and Viral Antagonism of Cholesterol Metabolism, Molecular Cell, vol.12, issue.4, pp.805-816, 2003.
DOI : 10.1016/S1097-2765(03)00384-8

D. Avila, H. Melo, R. Parreira, G. Werneck-barroso, E. Castro-faria-neto et al., Mycobacterium bovis Bacillus Calmette-Guerin Induces TLR2-Mediated Formation of Lipid Bodies: Intracellular Domains for Eicosanoid Synthesis In Vivo, The Journal of Immunology, vol.176, issue.5, pp.3087-3097, 2006.
DOI : 10.4049/jimmunol.176.5.3087

M. Kazemi, C. Mcdonald, J. Shigenaga, C. Grunfeld, and K. Feingold, Adipocyte Fatty Acid-Binding Protein Expression and Lipid Accumulation Are Increased During Activation of Murine Macrophages by Toll-Like Receptor Agonists, Arteriosclerosis, Thrombosis, and Vascular Biology, vol.25, issue.6, pp.1220-1224, 2005.
DOI : 10.1161/01.ATV.0000159163.52632.1b

G. Nicolaou and C. Erridge, Toll-like receptor-dependent lipid body formation in macrophage foam cell formation, Current Opinion in Lipidology, vol.21, issue.5, pp.427-433, 2010.
DOI : 10.1097/MOL.0b013e32833cacd5

C. Bandeira-melo, M. Phoofolo, and P. Weller, Extranuclear Lipid Bodies, Elicited by CCR3-mediated Signaling Pathways, Are the Sites of Chemokine-enhanced Leukotriene C4 Production in Eosinophils and Basophils, Journal of Biological Chemistry, vol.276, issue.25, pp.22779-22787, 2001.
DOI : 10.1074/jbc.M101436200

C. Matte, G. Maion, W. Mourad, and M. Olivier, Leishmania donovani-induced macrophages cyclooxygenase-2 and prostaglandin E2 synthesis, Parasite Immunology, vol.131, issue.4, pp.177-184, 2001.
DOI : 10.1074/jbc.271.32.19134