Clinical outcome of skin yaws lesions after treatment with benzathinebenzylpenicillin in a pygmy population in Lobaye, Central African Republic.

Alexandre Manirakiza (1) , Susana Vilas Boas (2) , Narcisse Beyam (3) , Germain Zadanga (1) , François Xavier Konamna (1) , Siméon P Njuimo (1) , Rémi Laganier (1)

1 Institut Pasteur de Bangui
2 Poste de santé de Mongoumba
3 United Nations Population Fund

ABSTRACT: BACKGROUND: Yaws is a bacterial skin and bone infectious disease caused by Treponema pallidum pertenue. It is endemic, particularly among pygmies in Central African Republic. To assess the clinical cure rate after treatment with benzathinepenicillin in this population, we conducted a cohort survey of 243 patients in the Lobaye region. FINDINGS AND CONCLUSION: The rate of healing of lesions after 5 months was 95.9%. This relatively satisfactory level of therapeutic response implies that yaws could be controlled in the Central African Republic. Thus, reinforcement of the management of new cases and of contacts is suggested.

Keywords: Yaws; Treatment; Central African Republic

Domains: Life Sciences [q-bio]; Santé publique et épidémiologie

Alexandre Manirakiza, Susana Vilas Boas, Narcisse Beyam, Germain Zadanga, François Xavier Konamna, et al.. Clinical outcome of skin yaws lesions after treatment with benzathinebenzylpenicillin in a pygmy population in Lobaye, Central African Republic.. BMC Research Notes, 2011, 4, pp.543. ⟨10.1186/1756-0500-4-543⟩. ⟨pasteur-00734480⟩