Severe Crimean-Congo haemorrhagic fever presented with massive retroperitoneal haemorrhage that recovered without antiviral treatment.

Mehrnaz Asadi Gharabaghi (1) , Sadegh Chinikar (2) , Seyyed Mojtaba Ghiasi (2) , Maryam Morady (2) , Taha Ahmadinejhad (1) , Koosha Paydary (1)

1 Department of Medicine, Imam Khomeini Hospital Complex
2 Department of Arboviruses and Viral Hemorrhagic Fevers [Tehran]

Crimean-Congo haemorrhagic fever (CCHF) is a tickborne viral zoonosis with up to 50% mortality in humans caused by CCHF virus belonging to the genus Nairovirus, family Bunyaviridae. The geographical distribution of CCHF cases corresponds closely with the distribution of principle tick vectors that is species of Hyaloma. The disease presents with non-specific febrile symptoms, but progress to a serious haemorrhagic syndrome that, soon after, a full blown multi organ failure may develop with prominent features of liver damage and bleeding diathesis. The authors present a case of a 39-year-old man with severe CCHF with retroperitoneal haemorrhage that recovered without ribavirin administration. The case was confirmed for CCHF by serological and molecular tests.

Domains: Life Sciences [q-bio]; Microbiology and Parasitology; Virology

Mehrnaz Asadi Gharabaghi, Sadegh Chinikar, Seyyed Mojtaba Ghiasi, Maryam Morady, Taha Ahmadinejhad, et al.. Severe Crimean-Congo haemorrhagic fever presented with massive retroperitoneal haemorrhage that recovered without antiviral treatment.. BMJ, 2011, 2011, epub ahead of print. ⟨10.1136/bcr.10.2010.3408⟩. ⟨pasteur-00748091⟩