ANTIMICROBIAL POTENTIAL OF SELECTED THIOSULFONATES-BASED BIOCIDES AND BIOSURFACTANTS AGAINST BACTERIA AND FUNGI

Anna Sotirova (1) , Tatyana Avramova (1) , Irina Lazarkevich (1) , Vera Lubenets (2) , Elena Karpenko (2) , Danka Galabova (1)

1 Institut Stephan Angeloff
2 Institute of Physical Chemistry

The antimicrobial potential of ethylthiosulfonate and methylthiosulfonate in absence and in presence of rhamnolipid-biosurfactant was investigated against Bacillus subtilis, Pseudomonas aeruginosa, Alcaligenes faecalis and Rhizopus nigricans. The results demonstrated that the bactericidal and fungicidal ef- fects of both inhibitors were well expressed. Methylthiosulfonate has a stronger antimicrobial effect. The presence of rhamnolipid-biosurfactant enhanced the bactericidal, sporocidal and fungicidal effect of inhibitors. The results indicate that ethylthiosulfonate and methylthiosulfonate alone or in combination with rhamnolipid-biosurfactant have a potential for application in industry to en- hance the effectiveness of the production process, in agriculture to minimize the presence of harmful phytopathogens and in biomedicine for new antimicro- bial drug therapy.

Keywords: ethylthiosulfonate; methylthiosulfonate; rhamnolipid-biosur- factant; B. subtilis; P. aeruginosa; A. faecalis and Rh. nigricans

Domains: Life Sciences [q-bio]; Microbiology and Parasitology

Anna Sotirova, Tatyana Avramova, Irina Lazarkevich, Vera Lubenets, Elena Karpenko, et al.. ANTIMICROBIAL POTENTIAL OF SELECTED THIOSULFONATES-BASED BIOCIDES AND BIOSURFACTANTS AGAINST BACTERIA AND FUNGI. Comptes rendus de l'Académie bulgare des Sciences, 2010, 63 (9), pp.1307-1314. ⟨pasteur-00748969⟩