Leishmania major Yakimoff et Schokhor, 1914 (Kinetoplastida : Trypanosomatidae) chez Meriones shawi Duvernoy, 1842 (Rodentia : Gerbillidae) : persistance de l'infection du mérion et de son infectivité pour le phlébotome vecteur Phlebotomus (Phlebotomus) papatasi Scopoli, 1786 (Diptera : Psychodidae)

Abstract : The ability of the sand fly Phlebotomus papatasi to transmit Leishmania major, the etiologic agent of zoonotic cutaneous leishmaniasis, to Meriones shawi, the natural reservoir host of this parasite, was studied under laboratory conditions. Sand flies became infected with L. major after feeding on a lesion of needle-inoculated M. shawi. Moreover, P. papatasi, previously infected with L. major, transmitted the parasite to M. shawi by bite during a second bloodmeal. Two months after the blood-meal, the animal developed a lesion on its ears. Xenodiagnosis was performed on the infected animal. The infectivity of M. shawi to P. papatasi lasted for five months, period corresponding to winter season in North Africa. We have thus demonstrated the transmission of L. major by P. papatasi to M. shawi under laboratory conditions. Our results show that reservoir hosts surviving winter time are the main source of infection for P. papatasi during the following season, and subsequently they play a major role in the persistence and transmission of L. major between transmission cycles.
Document type :
Journal articles
Complete list of metadatas

Cited literature [18 references]  Display  Hide  Download

https://hal-riip.archives-ouvertes.fr/pasteur-00750947
Contributor : Institut Pasteur Tunis <>
Submitted on : Monday, November 12, 2012 - 5:12:14 PM
Last modification on : Friday, October 11, 2019 - 10:09:31 AM
Long-term archiving on : Saturday, December 17, 2016 - 9:21:51 AM

File

 Restricted access
To satisfy the distribution rights of the publisher, the document is embargoed until : jamais

Please log in to resquest access to the document

Identifiers

Collections

Citation

M. Derbali, I. Chelbi, S. Ben Hadj Ahmed, E. Zhioua. Leishmania major Yakimoff et Schokhor, 1914 (Kinetoplastida : Trypanosomatidae) chez Meriones shawi Duvernoy, 1842 (Rodentia : Gerbillidae) : persistance de l'infection du mérion et de son infectivité pour le phlébotome vecteur Phlebotomus (Phlebotomus) papatasi Scopoli, 1786 (Diptera : Psychodidae). Bulletin de la Société de pathologie exotique , Masson, 2012, 105 (5), pp.399--402. ⟨10.1007/s13149-012-0259-4⟩. ⟨pasteur-00750947⟩

Share

Metrics

Record views

155