Evaluation of 17 medicinal plants from Northern Côte d'Ivoire for their in vitro activity against Streptococcus pneumoniae.

W Mamidou Koné; K Kamanzi Atindehou; A. Kacou-N'Douba; M. Dosso

Evaluation of 17 medicinal plants from Northern Côte d'Ivoire for their in vitro activity against Streptococcus pneumoniae.

W Mamidou Koné ^{1, 2, *} K Kamanzi Atindehou ^{2, 3} A. Kacou-N'Douba ⁴ M. Dosso ⁴

* Corresponding author

1 UFR Sciences de la Nature

2 Centre Suisse de Recherches Scientifiques (CSRS)

3 Laboratoire de Botanique, UFR Biosciences

4 Département de Bactériologie-Virologie

Abstract : Twenty crude extracts from 17 species out of 11 families were assessed for their antibacterial activity against Streptococcus pneumoniae (Pneumococcus). The selected plants are used in Northern Côte d'Ivoire to treat various infections including respiratory track diseases. From all the tested extracts, only 7 from 6 plants showed a promising in vitro bactericidal activity against Pneumococcus, including strains resistant to penicillin. The most active extracts were from Erythrina senegalensis (Fabaceae), Piliostigma thonningii (Caesalpiniaceae), Waltheria indica (Sterculiaceae), Andira inermis (Fabaceae), Uapaca togoensis (Euphorbiaceae), Keetia hispida (Rubiaceae) and Combretum molle (Combretaceae). This is the first time that the antipneumococcal activity of the tested plants is reported. The results of this preliminary investigation support the traditional use of these plants in the treatment of pneumococcal infections. The most active of them could be candidates for isolation of compounds which could serve as lead structures for the development of new drugs against Streptococcus pneumoniae.

Keywords : Streptococcus pneumoniae Antibacterial activity Côte d'Ivoire Medicinal plants Pneumococcus Streptococcus pneumoniae.

Document type :

Journal articles

Domain :

Life Sciences [q-bio] / Microbiology and Parasitology / Bacteriology

Complete list of metadatas

Cited literature [12 references] Display Hide Download

https://hal-riip.archives-ouvertes.fr/pasteur-00758521
Contributor : Mireille Dosso <>
Submitted on : Wednesday, November 28, 2012 - 5:46:04 PM
Last modification on : Thursday, May 16, 2019 - 4:02:14 PM
Long-term archiving on : Saturday, December 17, 2016 - 5:20:02 PM

evaluation_dosso.pdf

Publisher files allowed on an open archive

Evaluation of 17 medicinal plants from Northern Côte d'Ivoire for their in vitro activity against Streptococcus pneumoniae.

File

Identifiers

Collections

Citation

Export

Metrics

146

185

Contact

Evaluation of 17 medicinal plants from Northern Côte d'Ivoire for their in vitro activity against Streptococcus pneumoniae.

File

Identifiers

Collections

Citation

Export

Share

Metrics

146

185

Contact