Molecular epidemiology of clade 1 influenza A viruses (H5N1), southern Indochina peninsula, 2004-2007.

J S Malik Peiris (1) , Philippe Buchy (2) , Mathieu Fourment (2) , Sek Mardy (2) , San Sorn (3) , Davun Holl (3) , Sowath Ly (2) , Sirenda Vong (2) , Vincent Enouf (4) , J.S. Malik Peiris , Silvie van Der Werf (4)

1 Centre de recherche Université de Hong-Kong-Pasteur
2 Institut Pasteur du Cambodge
3 Ministry of Agriculture, Forestry and Fisheries [Cambodia]
4 Génétique moléculaire des virus à ARN

To determine the origin of influenza A virus (H5N1) epizootics in Cambodia, we used maximum-likelihood and Bayesian methods to analyze the genetic sequences of subtype H5N1 strains from Cambodia and neighboring areas. Poultry movements, rather than repeated reintroduction of subtype H5N1 viruses by wild birds, appear to explain virus circulation and perpetuation.

Keywords: Animals; Wild; Birds; Cambodia; Disease Outbreaks; Humans; Influenza A Virus; H5N1 Subtype; Influenza in Birds; Influenza; Human; Molecular Epidemiology; Time Factors

Domains: Virology

J S Malik Peiris, Philippe Buchy, Mathieu Fourment, Sek Mardy, San Sorn, et al.. Molecular epidemiology of clade 1 influenza A viruses (H5N1), southern Indochina peninsula, 2004-2007.. Emerging Infectious Diseases, 2009, 15 (10), pp.1641-4. ⟨10.3201/eid1510.090115⟩. ⟨pasteur-00808191⟩