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Liquid chromatography/mass spectrometry for the detection and quantification of N-acyl-L-homoserine lactones and 4-hydroxy-2-alkylquinolines.

François Lépine 1 Eric Déziel 1, * 
* Corresponding author
1 INRS-IAF - Institut Armand Frappier
Abstract : High-performance liquid chromatography (HPLC) coupled in-line with mass spectrometry (MS) permits rapid and specific identification and quantification of N-acyl-L-homoserine lactones (AHLs) and 4-hydroxy-2-alkylquinolines (HAQs). We are presenting here methods for the analysis of these molecules directly from biological samples using LC/MS.
Keywords : Bacteria Quorum sensing Acyl homoserine lactone 4-Hydroxy-2-alkylquinoline Analysis Quantification Mass spectrometry Liquid chromatography
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https://hal-riip.archives-ouvertes.fr/pasteur-00819401
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Submitted on : Wednesday, May 1, 2013 - 1:55:45 AM
Last modification on : Monday, October 8, 2018 - 5:44:04 PM

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François Lépine, Eric Déziel. Liquid chromatography/mass spectrometry for the detection and quantification of N-acyl-L-homoserine lactones and 4-hydroxy-2-alkylquinolines.. Methods in Molecular Biology, Humana Press/Springer Imprint, 2011, 692, pp.61-9. ⟨10.1007/978-1-60761-971-0_5⟩. ⟨pasteur-00819401⟩

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