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Journal articles
A chimeric measles virus with canine distemper envelope protects ferrets from lethal distemper challenge.
Abstract : CDV infects a broad range of carnivores, and over the past decades it has caused outbreaks in a variety of wild carnivore populations. Since the currently available live-attenuated vaccine is not sufficiently safe in these highly susceptible species, we produced a chimeric virus combining the replication complex of the measles Moraten vaccine strain with the envelope of a recent CDV wild type isolate. The resulting virus did not cause disease or immunosuppression in ferrets and conferred protection from challenge with a lethal wild type strain, demonstrating its potential value for wildlife conservation efforts.
https://hal-riip.archives-ouvertes.fr/pasteur-00819649
Contributor : Charles M. Dozois Connect in order to contact the contributor
Submitted on : Thursday, May 2, 2013 - 4:22:27 AM
Last modification on : Monday, October 8, 2018 - 5:44:04 PM
Contributor : Charles M. Dozois Connect in order to contact the contributor
Submitted on : Thursday, May 2, 2013 - 4:22:27 AM
Last modification on : Monday, October 8, 2018 - 5:44:04 PM