The origins and spread of antimalarial drug resistance: Lessons for policy makers, Acta Tropica, vol.94, issue.3, pp.269-280, 2005. ,
DOI : 10.1016/j.actatropica.2005.04.010
Plasmodium falciparum Drug Resistance in Madagascar: Facing the Spread of Unusual pfdhfr and pfmdr-1 Haplotypes and the Decrease of Dihydroartemisinin Susceptibility, Antimicrobial Agents and Chemotherapy, vol.53, issue.11, pp.4588-4597, 2009. ,
DOI : 10.1128/AAC.00610-09
URL : https://hal.archives-ouvertes.fr/pasteur-00741124
Efficacy and safety of intermittent preventive treatment with sulfadoxine-pyrimethamine for malaria in African infants: a pooled analysis of six randomised, placebo-controlled trials, The Lancet, vol.374, issue.9700, pp.1533-1542, 2009. ,
DOI : 10.1016/S0140-6736(09)61258-7
Invasion of Africa by a single pfcrt allele of South East Asian type, Malar. J, vol.26, p.34, 2006. ,
URL : https://hal.archives-ouvertes.fr/pasteur-00590988
DHFR and DHPS genotypes of Plasmodium falciparum isolates from Gabon correlate with in vitro activity of pyrimethamine and cycloguanil, but not with sulfadoxine-pyrimethamine treatment efficacy, Journal of Antimicrobial Chemotherapy, vol.52, issue.1, pp.43-49, 2003. ,
DOI : 10.1093/jac/dkg294
Amino acid changes linked to pyrimethamine resistance in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum., Proceedings of the National Academy of Sciences, vol.85, issue.23, pp.9109-9113, 1988. ,
DOI : 10.1073/pnas.85.23.9109
Simultaneous identification of the four human Plasmodium species and quantification of Plasmodium DNA load in human blood by real-time polymerase chain reaction, Transactions of the Royal Society of Tropical Medicine and Hygiene, vol.97, issue.4, pp.387-390, 2003. ,
DOI : 10.1016/S0035-9203(03)90065-4
Use of Molecular Beacons To Detect an Antifolate Resistance-Associated Mutation in Plasmodium falciparum, Antimicrobial Agents and Chemotherapy, vol.44, issue.12, pp.3461-3464, 2000. ,
DOI : 10.1128/AAC.44.12.3461-3464.2000
Mechanisms of Resistance of Malaria Parasites to Antifolates, Pharmacological Reviews, vol.57, issue.1, pp.117-145, 2005. ,
DOI : 10.1124/pr.57.1.4
A World Malaria Map: Plasmodium falciparum Endemicity in 2007, PLoS Medicine, vol.118, issue.3, p.1000048, 2007. ,
DOI : 10.1371/journal.pmed.1000048.sd009
Stepwise acquisition of pyrimethamine resistance in the malaria parasite, Proceedings of the National Academy of Sciences, vol.106, issue.29, pp.12025-12030, 2009. ,
DOI : 10.1073/pnas.0905922106
from Sites across Africa, The Journal of Infectious Diseases, vol.196, issue.1, pp.165-172, 2007. ,
DOI : 10.1086/518512
Hitchhiking and Selective Sweeps of Plasmodium falciparum Sulfadoxine and Pyrimethamine Resistance Alleles in a Population from Central Africa, Antimicrobial Agents and Chemotherapy, vol.52, issue.11, pp.4089-4097, 2008. ,
DOI : 10.1128/AAC.00623-08
Common Origin and Fixation of Plasmodium falciparum dhfr and dhps Mutations Associated with Sulfadoxine-Pyrimethamine Resistance in a Low-Transmission Area in South America, Antimicrobial Agents and Chemotherapy, vol.51, issue.6, pp.2085-2091, 2007. ,
DOI : 10.1128/AAC.01228-06
Alleles, The Journal of Infectious Diseases, vol.194, issue.2, pp.189-197, 2006. ,
DOI : 10.1086/504687
The Bill & Melinda Gates Foundation's grant-making programme for global health, The Lancet, vol.373, issue.9675, pp.1645-1653, 2009. ,
DOI : 10.1016/S0140-6736(09)60571-7
Drug-Resistant Malaria Parasites Introduced into Madagascar from Comoros Islands, Emerging Infectious Diseases, vol.13, issue.11, pp.1759-1762, 2007. ,
DOI : 10.3201/eid1311.070235
Assessment of the efficacy of antimalarial drugs recommended by the National Malaria Control Programme in Madagascar: Up-dated baseline data from randomized and multi-site clinical trials, Malaria Journal, vol.7, issue.1, p.55, 2008. ,
DOI : 10.1186/1475-2875-7-55
Spread and evolution of Plasmodium falciparum drug resistance, Parasitology International, vol.58, issue.3, pp.201-209, 2009. ,
DOI : 10.1016/j.parint.2009.04.004
Adaptive Copy Number Evolution in Malaria Parasites, PLoS Genetics, vol.3, issue.2, p.1000243, 2008. ,
DOI : 10.1371/journal.pgen.1000243.s007
A Selective Sweep Driven by Pyrimethamine Treatment in Southeast Asian Malaria Parasites, Molecular Biology and Evolution, vol.20, issue.9, pp.1526-1536, 2003. ,
DOI : 10.1093/molbev/msg162
Epidemiology of drug-resistant malaria in Republic of Congo: using molecular evidence for monitoring antimalarial drug resistance combined with assessment of antimalarial drug use, Tropical Medicine and International Health, vol.15, issue.10, pp.1030-1037, 2005. ,
DOI : 10.1016/S0001-706X(03)00021-4
Antimalarial drug susceptibility and point mutations associated with drug resistance in 248 Plasmodium falciparum isolates imported from Comoros, Am. J. Trop. Med. Hyg, vol.77, pp.431-437, 2004. ,
Reduced Variation Around Drug-Resistant dhfr Alleles in African Plasmodium falciparum, Molecular Biology and Evolution, vol.22, issue.9, pp.1834-1844, 2005. ,
DOI : 10.1093/molbev/msi177
Short report: high prevalence of multidrugresistant Plasmodium falciparum malaria in the French territory of Mayotte, Am. J. Trop. Med. Hyg, vol.70, pp.635-637, 2004. ,
P. falciparum dihydrofolate reductase and dihydropteroate synthase mutations: epidemiology and role in clinical resistance to antifolates, Drug Resistance Updates, vol.1, issue.6, pp.389-396, 1998. ,
DOI : 10.1016/S1368-7646(98)80014-9
Accuracy and reliability of malaria diagnostic techniques for guiding febrile outpatient treatment in malaria-endemic countries, Am. J. Trop. Med. Hyg, vol.78, pp.217-221, 2008. ,
Plasmodium falciparum resistant to chloroquine and to pyrimethamine in Comoros, Parasite, vol.11, pp.419-423, 2004. ,
Intercontinental Spread of Pyrimethamine-Resistant Malaria, Science, vol.305, issue.5687, p.1124, 2004. ,
DOI : 10.1126/science.1098876
Pyrimethamine-resistant dihydrofolate reductase enzymes of Plasmodium falciparum are not enzymatically compromised in vitro, Molecular and Biochemical Parasitology, vol.154, issue.1, pp.1-5, 2007. ,
DOI : 10.1016/j.molbiopara.2007.03.009
International Funding for Malaria Control in Relation to Populations at Risk of Stable Plasmodium falciparum Transmission, PLoS Medicine, vol.12, issue.7, p.142, 2008. ,
DOI : 10.1371/journal.pmed.0050142.st001
Efficacy of artesunate plus amodiaquine, artesunate plus sulfadoxine-pyrimethamine, and chloroquine plus sulfadoxine-pyrimethamine in patients with uncomplicated Plasmodium falciparum in the Comoros Union, Acta Tropica, vol.102, issue.3, pp.176-181, 2007. ,
DOI : 10.1016/j.actatropica.2007.03.004
Epidemiology and prevention of malaria in the southwestern islands of the Indian Ocean, Med. Trop. (Mars.), vol.66, pp.295-301, 2006. ,
A genome-wide map of diversity in Plasmodium falciparum, Nature Genetics, vol.419, issue.1, pp.113-119, 2007. ,
DOI : 10.1038/ng1930