M. G. Vallespi, J. R. Fernandez, and I. Torrens, Identification of a novel antitumor peptide based on the screening of an Ala-library derived from the LALF32??????51 region, Journal of Peptide Science, vol.1, issue.1, pp.40-47, 2010.
DOI : 10.1002/psc.1192

M. G. Vallespi, J. R. Fernandez-masso, A. Musacchio-lasa, J. G. Valdez, O. R. Acosta et al., Cancer ?erapy method, 2011.

P. De-bie, B. Van-de-sluis, L. Klomp, and C. Wijmenga, The Many Faces of the Copper Metabolism Protein MURR1/COMMD1, Journal of Heredity, vol.96, issue.7, pp.803-811, 2005.
DOI : 10.1093/jhered/esi110

T. Chang, Y. Ke, K. Ly, and F. J. Mcdonald, COMMD1 regulates the delta epithelial sodium channel (??ENaC) through trafficking and ubiquitination, Biochemical and Biophysical Research Communications, vol.411, issue.3, pp.506-511, 2011.
DOI : 10.1016/j.bbrc.2011.06.149

P. De-bie, B. Van-de-sluis, and E. Burstein, Characterization of COMMD protein???protein interactions in NF-??B signalling, Biochemical Journal, vol.398, issue.1, pp.63-71, 2006.
DOI : 10.1042/BJ20051664

B. Van-de-sluis, P. Muller, and K. Duran, Increased Activity of Hypoxia-Inducible Factor 1 Is Associated with Early Embryonic Lethality in Commd1 Null Mice, Molecular and Cellular Biology, vol.27, issue.11, pp.4142-4156, 2007.
DOI : 10.1128/MCB.01932-06

H. Geng, T. Wittwer, O. Dittrich-breiholz, M. Kracht, and M. L. Schmitz, Phosphorylation of NF-??B p65 at Ser468 controls its COMMD1-dependent ubiquitination and target gene-specific proteasomal elimination, EMBO reports, vol.19, issue.4, pp.381-386, 2009.
DOI : 10.1016/S1097-2765(00)80066-0

G. N. Maine, X. Mao, C. M. Komarck, and E. Burstein, COMMD1 promotes the ubiquitination of NF-??B subunits through a cullin-containing ubiquitin ligase, The EMBO Journal, vol.9, issue.2, pp.436-447, 2007.
DOI : 10.1038/sj.emboj.7601489

S. Materia, M. A. Cater, L. W. Klomp, J. F. Mercer, and S. La-fontaine, Clusterin and COMMD1 Independently Regulate Degradation of the Mammalian Copper ATPases ATP7A and ATP7B, Journal of Biological Chemistry, vol.287, issue.4, pp.2485-2499, 2012.
DOI : 10.1074/jbc.M111.302216

B. Van-de-sluis, A. J. Groot, and J. Vermeulen, COMMD1 promotes pVHL and O 2 -independent proteolysis of HIF-1í µí»¼í µí»¼ via HSP90, PLoS One, vol.70, issue.4 10, 2009.

G. Xiao and J. Fu, NF-í µí¼…í µí¼…B and cancer: a paradigm of Yin-Yang, American Journal of Cancer Research, vol.1, issue.2, pp.192-221, 2011.

E. Poon, A. L. Harris, and M. Ashcro?, Targeting the hypoxia-inducible factor (HIF) pathway in cancer, Expert Reviews in Molecular Medicine, vol.1755, p.26, 2009.
DOI : 10.1016/j.rcl.2004.08.004

B. Van-de-sluis, X. Mao, and Y. Zhai, COMMD1 disrupts HIF-1??/?? dimerization and inhibits human tumor cell invasion, Journal of Clinical Investigation, vol.120, issue.6, pp.2119-2130, 2010.
DOI : 10.1172/JCI40583DS1

C. Camacho, G. Coulouris, and V. Avagyan, BLAST+: architecture and applications, BMC Bioinformatics, vol.10, issue.1, p.421, 2009.
DOI : 10.1186/1471-2105-10-421

I. Vancurova, V. Miskolci, and D. Davidson, NF-??B Activation in Tumor Necrosis Factor ??-stimulated Neutrophils Is Mediated by Protein Kinase C??, Journal of Biological Chemistry, vol.276, issue.23, pp.19746-19752, 2001.
DOI : 10.1074/jbc.M100234200

H. Towbin and J. Gordon, Immunoblotting and dot immunobinding ??? Current status and outlook, Journal of Immunological Methods, vol.72, issue.2, pp.313-340, 1984.
DOI : 10.1016/0022-1759(84)90001-2

C. A. Schneider, W. S. Rasband, and K. W. Eliceiri, NIH Image to ImageJ: 25 years of image analysis, Nature Methods, vol.42, issue.7, pp.671-675, 2012.
DOI : 10.1038/nmeth.2089

W. Cui, D. D. Taub, and K. Gardner, qPrimerDepot: a primer database for quantitative real time PCR, Nucleic Acids Research, vol.35, issue.Database, pp.805-809, 2007.
DOI : 10.1093/nar/gkl767

S. A. Bustin, J. F. Beaulieu, and J. Huggett, MIQE pr??cis: Practical implementation of minimum standard guidelines for fluorescence-based quantitative real-time PCR experiments, BMC Molecular Biology, vol.11, issue.1, 2010.
DOI : 10.1186/1471-2199-11-74

J. Vandesompele, K. De-preter, and F. Pattyn, Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes, Genome biology, vol.3, issue.7, p.34, 2002.

M. W. Pfa?, G. W. Horgan, and L. Demp?e, Relative expression so?ware tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR, Nucleic Acids Research, vol.30, issue.9, p.36, 2002.

M. M. Bradford, A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding, Analytical Biochemistry, vol.72, issue.1-2, pp.248-254, 1976.
DOI : 10.1016/0003-2697(76)90527-3

H. Ukeda, S. Maeda, T. Ishii, and M. Sawamura, Spectrophotometric Assay for Superoxide Dismutase Based on Tetrazolium Salt 3???-{1-[(Phenylamino)-carbonyl]-3,4-tetrazolium}-bis(4-methoxy-6-nitro)benzenesulfonic Acid Hydrate Reduction by Xanthine???Xanthine Oxidase, Analytical Biochemistry, vol.251, issue.2, pp.206-209, 1997.
DOI : 10.1006/abio.1997.2273

V. Witko-sarsat, M. Friedlander, and T. N. Khoa, Advanced oxidation protein products as novel mediators of in?ammation and monocyte activation in chronic renal failure, Journal of Immunology, vol.161, issue.5, pp.2524-2532, 1998.

I. Erdelmeier, D. Gérard-monnier, J. C. Yadan, and J. Chaudière, -Methyl-2-phenylindole with Malondialdehyde and 4-Hydroxyalkenals. Mechanistic Aspects of the Colorimetric Assay of Lipid Peroxidation, Chemical Research in Toxicology, vol.11, issue.10, pp.1184-1194, 1998.
DOI : 10.1021/tx970180z

I. F. Benzie and J. J. Strain, The Ferric Reducing Ability of Plasma (FRAP) as a Measure of ???Antioxidant Power???: The FRAP Assay, Analytical Biochemistry, vol.239, issue.1, pp.70-76, 1996.
DOI : 10.1006/abio.1996.0292

A. Zoubeidi, S. Ettinger, and E. Beraldi, Clusterin Facilitates COMMD1 and I-??B Degradation to Enhance NF-??B Activity in Prostate Cancer Cells, Molecular Cancer Research, vol.8, issue.1, pp.119-130, 2010.
DOI : 10.1158/1541-7786.MCR-09-0277

P. A. Muller, B. V. De-sluis, and A. J. Groot, Nuclear-Cytosolic Transport of COMMD1 Regulates NF-??B and HIF-1 Activity, Traffic, vol.17, issue.2, pp.514-527, 2009.
DOI : 10.1111/j.1600-0854.2009.00892.x

H. C. ?oms, C. J. Loveridge, and J. Simpson, Nucleolar targeting of RelA(p65) is regulated by COMMD1-dependent ubiquitination, Cancer Research, vol.70, issue.1, pp.139-149, 2010.

W. I. Vonk, C. Wijmenga, R. Berger, B. Van-de-sluis, and L. W. Klomp, Cu,Zn Superoxide Dismutase Maturation and Activity Are Regulated by COMMD1, Journal of Biological Chemistry, vol.285, issue.37, pp.28991-29000, 2010.
DOI : 10.1074/jbc.M110.101477

P. Vlieghe, V. Lisowski, J. Martinez, and M. Khrestchatisky, Synthetic therapeutic peptides: science and market, Drug Discovery Today, vol.15, issue.1-2, pp.40-56, 2010.
DOI : 10.1016/j.drudis.2009.10.009

G. N. Maine, X. Mao, P. A. Muller, C. M. Komarck, L. W. Klomp et al., COMMD1 expression is controlled by critical residues that determine XIAP binding, Biochemical Journal, vol.417, issue.2, pp.601-609, 2009.
DOI : 10.1042/BJ20080854

Y. Ben-neriah and M. Karin, Inflammation meets cancer, with NF-??B as the matchmaker, Nature Immunology, vol.104, issue.8, pp.715-723, 2011.
DOI : 10.1038/nature09673

G. N. Maine and E. Burstein, COMMD Proteins and the Control of the NF??B Pathway, Cell Cycle, vol.6, issue.6, pp.672-676, 2007.
DOI : 10.4161/cc.6.6.3989

H. Pelicano, D. Carney, and P. Huang, ROS stress in cancer cells and therapeutic implications, Drug Resistance Updates, vol.7, issue.2, pp.97-110, 2004.
DOI : 10.1016/j.drup.2004.01.004

A. A. Dayem, H. Y. Choi, J. H. Kim, and S. G. Cho, Role of Oxidative Stress in Stem, Cancer, and Cancer Stem Cells, Cancers, vol.2, issue.2, pp.859-884, 2010.
DOI : 10.3390/cancers2020859