Apple can act as anti-aging on yeast cells.

Vanessa Palermo (1) , Fulvio Mattivi (2) , Romano Silvestri (3) , Giuseppe La Regina (3) , Claudio Falcone (1) , Cristina Mazzoni (1)

1 Department of Biology and Biotechnology "Charles Darwin"
2 Food Quality and Nutrition Department
3 Department of Drug Chemistry and Technologies = Dipartimento di Chimica et Tecnologie del Farmaco [Roma]

In recent years, epidemiological and biochemical studies have shown that eating apples is associated with reduction of occurrence of cancer, degenerative, and cardiovascular diseases. This association is often attributed to the presence of antioxidants such as ascorbic acid (vitamin C) and polyphenols. The substances that hinder the presence of free radicals are also able to protect cells from aging. In our laboratory we used yeast, a unicellular eukaryotic organism, to determine in vivo efficacy of entire apples and their components, such as flesh, skin and polyphenolic fraction, to influence aging and oxidative stress. Our results indicate that all the apple components increase lifespan, with the best result given by the whole fruit, indicating a cooperative role of all apple components.

Domains: Biochemistry, Molecular Biology

Vanessa Palermo, Fulvio Mattivi, Romano Silvestri, Giuseppe La Regina, Claudio Falcone, et al.. Apple can act as anti-aging on yeast cells.. Oxidative Medicine and Cellular Longevity, 2012, 2012, pp.491759. ⟨10.1155/2012/491759⟩. ⟨pasteur-00952141⟩