Neurospora wc-1 and wc-2: Transcription, Photoresponses, and the Origins of Circadian Rhythmicity, Science, vol.276, issue.5313, pp.763-769, 1997. ,
DOI : 10.1126/science.276.5313.763
Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1??: modulation by p38 MAPK, Genes & Development, vol.18, issue.3, pp.278-289, 2004. ,
DOI : 10.1101/gad.1152204
White Collar-1, a Circadian Blue Light Photoreceptor, Binding to the frequency Promoter, Science, vol.297, issue.5582, pp.815-819, 2002. ,
DOI : 10.1126/science.1073681
Epigenetic regulation by nuclear receptors, Epigenomics, vol.3, issue.1, pp.59-72, 2011. ,
DOI : 10.2217/epi.10.75
The Neurospora crassa White Collar-1 dependent Blue Light Response Requires Acetylation of Histone H3 Lysine 14 by NGF-1, Molecular Biology of the Cell, vol.17, issue.10, pp.14-15, 2006. ,
DOI : 10.1091/mbc.E06-03-0232
Principles for modulation of the nuclear receptor superfamily, Nature Reviews Drug Discovery, vol.97, issue.11, pp.950-964, 2004. ,
DOI : 10.1242/jcs.00247
White Collar-1, a DNA Binding Transcription Factor and a Light Sensor, Science, vol.297, issue.5582, pp.840-843, 2002. ,
DOI : 10.1126/science.1072795
circadian clock protein FREQUENCY through the ubiquitin???proteasome pathway, Biochemical Society Transactions, vol.33, issue.5, pp.953-956, 2005. ,
DOI : 10.1042/BST0330953
The PAS Protein VIVID Defines a Clock-Associated Feedback Loop that Represses Light Input, Modulates Gating, and Regulates Clock Resetting, Cell, vol.104, issue.3, pp.453-464, 2001. ,
DOI : 10.1016/S0092-8674(01)00232-X
Key roles for MED1 LxxLL motifs in pubertal mammary gland development and luminal-cell differentiation, Proceedings of the National Academy of Sciences, vol.107, issue.15, pp.6765-6770, 2010. ,
DOI : 10.1073/pnas.1001814107
Interconnected Feedback Loops in the Neurospora Circadian System, Science, vol.289, issue.5476, pp.107-110, 2000. ,
DOI : 10.1126/science.289.5476.107
White collar 2,a partner in blue-light signal transduction, controlling expression of light-regulated genes in Neurospora crassa, The EMBO Journal, vol.16, issue.1, pp.98-109, 1997. ,
DOI : 10.1093/emboj/16.1.98
Photoreception in Neurospora : a tale of two White Collar proteins, Cellular and Molecular Life Sciences (CMLS), vol.60, issue.10, pp.2131-2138, 2003. ,
DOI : 10.1007/s00018-003-3109-5
In situ distinction between steroid receptor binding and transactivation at a target gene., Molecular and Cellular Biology, vol.11, issue.9, pp.4350-4355, 1991. ,
DOI : 10.1128/MCB.11.9.4350
Nuclear receptor-like transcription factors in fungi, Genes & Development, vol.23, issue.4, pp.419-432, 2009. ,
DOI : 10.1101/gad.1743009
The bromodomain of Gcn5p interacts in vitro with specific residues in the N terminus of histone H4, Journal of Molecular Biology, vol.287, issue.1, pp.1-7, 1999. ,
DOI : 10.1006/jmbi.1999.2577
Histone Acetyltransferases, Annual Review of Biochemistry, vol.70, issue.1, pp.81-120, 2001. ,
DOI : 10.1146/annurev.biochem.70.1.81
Regulation of Conidiation by Light in Aspergillus nidulans, Genetics, vol.188, issue.4, pp.809-822, 2011. ,
DOI : 10.1534/genetics.111.130096
The coactivator LXXLL nuclear receptor recognition motif, Journal of Peptide Research, vol.98, issue.3, pp.207-212, 2004. ,
DOI : 10.1073/pnas.1934759100
The structural basis of androgen receptor activation: Intramolecular and intermolecular amino-carboxy interactions, Proceedings of the National Academy of Sciences, vol.102, issue.28, pp.9802-9807, 2005. ,
DOI : 10.1073/pnas.0408819102
Acetylation of Histones and Transcription-Related Factors, Microbiology and Molecular Biology Reviews, vol.64, issue.2, pp.435-459, 2000. ,
DOI : 10.1128/MMBR.64.2.435-459.2000
Role of a white collar-1-white collar-2 complex in blue-light signal transduction, The EMBO Journal, vol.18, issue.18, pp.4961-4968, 1999. ,
DOI : 10.1093/emboj/18.18.4961
Resurrecting the Ancestral Steroid Receptor: Ancient Origin of Estrogen Signaling, Science, vol.301, issue.5640, pp.1714-1717, 2003. ,
DOI : 10.1126/science.1086185
Application of a Fluorescent Histone Acetyltransferase Assay to Probe the Substrate Specificity of the Human p300/CBP-Associated Factor, Analytical Biochemistry, vol.287, issue.2, pp.319-328, 2000. ,
DOI : 10.1006/abio.2000.4855
Androgen receptor coregulators: Recruitment via the coactivator binding groove, Molecular and Cellular Endocrinology, vol.352, issue.1-2, pp.57-69, 2011. ,
DOI : 10.1016/j.mce.2011.08.007
Acetylation and nuclear receptor action, The Journal of Steroid Biochemistry and Molecular Biology, vol.123, issue.3-5, pp.91-100, 2011. ,
DOI : 10.1016/j.jsbmb.2010.12.003
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056342
Control of nuclear receptor function by local chromatin structure, FEBS Journal, vol.456, issue.266, pp.2211-2230, 2011. ,
DOI : 10.1111/j.1742-4658.2011.08126.x
Dynamics of coactivator recruitment and chromatin modifications during nuclear receptor mediated transcription, Molecular and Cellular Endocrinology, vol.280, issue.1-2, pp.1-5, 2008. ,
DOI : 10.1016/j.mce.2007.08.016
Photoregulation of the albino-3 gene in Neurospora crassa, Journal of Photochemistry and Photobiology B: Biology, vol.11, issue.2, pp.107-115, 1991. ,
DOI : 10.1016/1011-1344(91)80253-E
Nuclear Receptor Structure: Implications for Function, Annual Review of Physiology, vol.69, issue.1, pp.201-220, 2007. ,
DOI : 10.1146/annurev.physiol.69.031905.160308
Roles in dimerization and blue light photoresponse of the PAS and LOV domains of Neurospora crassa white collar proteins, Molecular Microbiology, vol.29, issue.3, pp.719-729, 1998. ,
DOI : 10.1038/39086
CHD1 Remodels Chromatin and Influences Transient DNA Methylation at the Clock Gene frequency, PLoS Genetics, vol.28, issue.7, 2011. ,
DOI : 10.1371/journal.pgen.1002166.s009
Execution of the Circadian Negative Feedback Loop in Neurospora Requires the ATP-Dependent Chromatin-Remodeling Enzyme CLOCKSWITCH, Molecular Cell, vol.25, issue.4, pp.587-600, 2007. ,
DOI : 10.1016/j.molcel.2007.01.010
Molecular characterization of upstream regulatory sequences controlling the photoinduced expression of the albino-3 gene of Neurospora crassa, Molecular Microbiology, vol.30, issue.5, pp.787-795, 1994. ,
DOI : 10.1073/pnas.74.12.5463
Genome-wide analysis of light-inducible responses reveals hierarchical light signalling in Neurospora, The EMBO Journal, vol.51, issue.8, pp.1029-1042, 2009. ,
DOI : 10.1021/bi982543f
PAS Domain-Mediated WC-1/WC-2 Interaction Is Essential for Maintaining the Steady-State Level of WC-1 and the Function of Both Proteins in Circadian Clock and Light Responses of Neurospora, Molecular and Cellular Biology, vol.22, issue.2, pp.517-524, 2002. ,
DOI : 10.1128/MCB.22.2.517-524.2002
Interlocked feedback loops contribute to the robustness of the Neurospora circadian clock, Proceedings of the National Academy of Sciences, vol.98, issue.13, pp.7408-7413, 2001. ,
DOI : 10.1073/pnas.121170298
WHITE COLLAR-1, a Multifunctional Neurospora Protein Involved in the Circadian Feedback Loops, Light Sensing, and Transcription Repression of wc-2, Journal of Biological Chemistry, vol.278, issue.6, pp.3801-3808, 2003. ,
DOI : 10.1074/jbc.M209592200
Photoexcited Structure of a Plant Photoreceptor Domain Reveals a Light-Driven Molecular Switch, THE PLANT CELL ONLINE, vol.14, issue.5, pp.1067-1075, 2002. ,
DOI : 10.1105/tpc.010475
We thank Alberto Gualtieri and Raffaele Gerace for their assistance in setting up the acetylation assay and bioinformatic analysis , respectively. We also thank Francesca Spadaro for scientific collaboration . A.B. is a Teresa Ariaudo Fellowship scholar ,