M. Rowe, G. Kelly, A. Bell, and A. Rickinson, Burkitt's lymphoma: The Rosetta Stone deciphering Epstein-Barr virus biology, Seminars in Cancer Biology, vol.19, issue.6, pp.377-388, 2009.
DOI : 10.1016/j.semcancer.2009.07.004

M. Rabson, L. Gradoville, L. Heston, and G. Miller, Non-immortalizing P3J-HR-1 Epstein- Barr virus: a deletion mutant of its transforming parent, Jijoye, J Virol, vol.44, pp.834-844, 1982.

A. Marchini, E. Kieff, and R. Longnecker, Marker rescue of a transformation-negative Epstein-Barr virus recombinant from an infected Burkitt lymphoma cell line: a method useful for analysis of genes essential for transformation, J Virol, vol.67, pp.606-609, 1993.

N. Jochner, D. Eick, U. Zimber-strobl, M. Pawlita, G. Bornkamm et al., Epstein-Barr virus nuclear antigen 2 is a transcriptional suppressor of the immunoglobulin mu gene: implications for the expression of the translocated c-myc gene in Burkitt's lymphoma cells, EMBO J, vol.15, pp.375-382, 1996.

G. Macarthur, G. Farrell, and P. , Epstein-Barr virus and Burkitt lymphoma, J Clin Pathol, vol.60, pp.1397-1402, 2007.

S. Grossman, E. Johannsen, X. Tong, R. Yalamanchili, and E. Kieff, The Epstein-Barr virus nuclear antigen 2 transactivator is directed to response elements by the J kappa recombination signal binding protein., Proceedings of the National Academy of Sciences, vol.91, issue.16, pp.7568-7572, 1994.
DOI : 10.1073/pnas.91.16.7568

G. Laux, F. Dugrillon, C. Eckert, B. Adam, U. Zimber-strobl et al., Identification and characterization of an Epstein-Barr virus nuclear antigen 2-responsive cis element in the bidirectional promoter region of latent membrane protein and terminal protein 2 genes, J Virol, vol.68, pp.6947-6958, 1994.

E. Johannsen, E. Koh, G. Mosialos, X. Tong, E. Kieff et al., Epstein-Barr virus nuclear protein 2 transactivation of the latent membrane protein 1 promoter is mediated by J kappa and PU.1, J Virol, vol.69, pp.253-262, 1995.

L. Wang, S. Grossman, and E. Kieff, Epstein-Barr virus nuclear protein 2 interacts with p300, CBP, and PCAF histone acetyltransferases in activation of the LMP1 promoter, Proceedings of the National Academy of Sciences, vol.97, issue.1, pp.430-435, 2000.
DOI : 10.1073/pnas.97.1.430

W. Lucchesi, G. Brady, O. Dittrich-breiholz, M. Kracht, R. Russ et al., Differential Gene Regulation by Epstein-Barr Virus Type 1 and Type 2 EBNA2, Journal of Virology, vol.82, issue.15, pp.7456-7466, 2008.
DOI : 10.1128/JVI.00223-08

F. Boccellato, E. Anastasiadou, P. Rosato, B. Kempkes, L. Frati et al., EBNA2 Interferes with the Germinal Center Phenotype by Downregulating BCL6 and TCL1 in Non-Hodgkin's Lymphoma Cells, Journal of Virology, vol.81, issue.5, pp.2274-2283, 2007.
DOI : 10.1128/JVI.01822-06

B. Zhao, S. Maruo, A. Cooper, M. Chase, E. Johannsen et al., RNAs induced by Epstein-Barr virus nuclear antigen 2 in lymphoblastoid cell lines, Proceedings of the National Academy of Sciences, vol.103, issue.6, pp.1900-1905, 2006.
DOI : 10.1073/pnas.0510612103

G. Calin and C. Croce, Chromosomal rearrangements and microRNAs: a new cancer link with clinical implications, Journal of Clinical Investigation, vol.117, issue.8, pp.2059-2066, 2007.
DOI : 10.1172/JCI32577

S. Pfeffer, M. Zavolan, F. Grasser, M. Chien, J. Russo et al., Identification of Virus-Encoded MicroRNAs, Science, vol.304, issue.5671, pp.734-736, 2004.
DOI : 10.1126/science.1096781

J. Kluiver, A. Van-den-berg, D. De-jong, T. Blokzijl, G. Harms et al., Regulation of pri-microRNA BIC transcription and processing in Burkitt lymphoma, Oncogene, vol.280, issue.26, pp.3769-3776, 2007.
DOI : 10.1038/sj.onc.1210147

J. Kluiver, E. Haralambieva, D. De-jong, T. Blokzijl, S. Jacobs et al., Lack ofBIC and microRNA miR-155 expression in primary cases of Burkitt lymphoma, Genes, Chromosomes and Cancer, vol.22, issue.2, pp.147-153, 2006.
DOI : 10.1002/gcc.20273

F. Lu, A. Weidmer, C. Liu, S. Volinia, C. Croce et al., Epstein-Barr Virus-Induced miR-155 Attenuates NF-??B Signaling and Stabilizes Latent Virus Persistence, Journal of Virology, vol.82, issue.21, pp.10436-10443, 2008.
DOI : 10.1128/JVI.00752-08
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2573162

J. Cameron, Q. Yin, C. Fewell, M. Lacey, J. Mcbride et al., Epstein-Barr Virus Latent Membrane Protein 1 Induces Cellular MicroRNA miR-146a, a Modulator of Lymphocyte Signaling Pathways, Journal of Virology, vol.82, issue.4, pp.1946-1958, 2008.
DOI : 10.1128/JVI.02136-07

N. Motsch, T. Pfuhl, J. Mrazek, S. Barth, and F. Grasser, Epstein-Barr Virus-Encoded Latent Membrane Protein 1 (LMP1) Induces the Expression of the Cellular MicroRNA miR-146a, RNA Biology, vol.4, issue.3, pp.131-137, 2007.
DOI : 10.4161/rna.4.3.5206

E. Anastasiadou, F. Boccellato, S. Vincenti, P. Rosato, I. Bozzoni et al., Epstein???Barr virus encoded LMP1 downregulates TCL1 oncogene through miR-29b, Oncogene, vol.56, issue.9, pp.1316-1328, 2010.
DOI : 10.1074/jbc.M708218200

M. Shimakage, A. Kurata, H. Inoue, Y. Okamoto, M. Yutsudo et al., Tumorigenicity of EBNA2-transfected cells, FEBS Lett, vol.371, pp.245-248, 1995.

S. Tai, C. Lin, C. Hsu, W. Chou, S. Lai et al., Epstein-Barr virus nuclear antigen 2 disrupts mitotic checkpoint and causes chromosomal instability, Carcinogenesis, vol.30, pp.366-375, 2009.

J. Tornell, S. Farzad, A. Espander-jansson, G. Matejka, O. Isaksson et al., Expression of Epstein-Barr nuclear antigen 2 in kidney tubule cells induce tumors in transgenic mice, Oncogene, vol.12, pp.1521-1528, 1996.

R. Amini, M. Berglund, R. Rosenquist, V. Heideman, A. Lagercrantz et al., A Novel B-cell Line (U-2932) Established from a Patient with Diffuse Large B-cell Lymphoma Following Hodgkin Lymphoma, Leukemia & Lymphoma, vol.29, issue.11, pp.2179-2189, 2002.
DOI : 10.1016/S0046-8177(99)90141-7

P. Trivedi, Q. Zhang, F. Chen, J. Minarovits, M. Ekman et al., Parallel existence of Epstein-Barr virus (EBV) positive and negative cells in a sporadic case of Burkitt lymphoma, Oncogene, vol.113, pp.505-510, 1995.

B. Kempkes, D. Spitkovsky, P. Jansen-durr, J. Ellwart, E. Kremmer et al., B-cell proliferation and induction of early G1-regulating proteins by Epstein-Barr virus mutants conditional for EBNA2, EMBO J, vol.14, pp.88-96, 1995.

S. Maruo, L. Yang, and K. Takada, Roles of Epstein???Barr virus glycoproteins gp350 and gp25 in the infection of human epithelial cells, Journal of General Virology, vol.82, issue.10, pp.2373-2383, 2001.
DOI : 10.1099/0022-1317-82-10-2373

K. Taganov, M. Boldin, K. Chang, and D. Baltimore, NF-??B-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses, Proceedings of the National Academy of Sciences, vol.103, issue.33, pp.12481-12486, 2006.
DOI : 10.1073/pnas.0605298103

Y. Yamanaka, H. Tagawa, N. Takahashi, A. Watanabe, Y. Guo et al., Aberrant overexpression of microRNAs activate AKT signaling via down-regulation of tumor suppressors in natural killer-cell lymphoma/leukemia, Blood, vol.114, issue.15, pp.3265-3275, 2009.
DOI : 10.1182/blood-2009-06-222794

J. Testa and A. Bellacosa, AKT plays a central role in tumorigenesis, Proceedings of the National Academy of Sciences, vol.98, issue.20, pp.10983-10985, 2001.
DOI : 10.1073/pnas.211430998

S. Godshalk, E. Bhaduri-mcintosh, and F. Slack, Epstein-Barr virus-mediated dysregulation of human microRNA expression, Cell Cycle, vol.7, issue.22, pp.3595-3600, 2008.
DOI : 10.4161/cc.7.22.7120

J. Chan, A. Krichevsky, and K. Kosik, MicroRNA-21 Is an Antiapoptotic Factor in Human Glioblastoma Cells, Cancer Research, vol.65, issue.14, pp.6029-6033, 2005.
DOI : 10.1158/0008-5472.CAN-05-0137

S. Volinia, G. Calin, C. Liu, S. Ambs, A. Cimmino et al., A microRNA expression signature of human solid tumors defines cancer gene targets, Proceedings of the National Academy of Sciences, vol.103, issue.7, pp.2257-2261, 2006.
DOI : 10.1073/pnas.0510565103

T. Wong, X. Liu, B. Wong, R. Ng, A. Yuen et al., Mature miR-184 as Potential Oncogenic microRNA of Squamous Cell Carcinoma of Tongue, Clinical Cancer Research, vol.14, issue.9, pp.2588-2592, 2008.
DOI : 10.1158/1078-0432.CCR-07-0666

M. Iorio, M. Ferracin, C. Liu, A. Veronese, R. Spizzo et al., MicroRNA Gene Expression Deregulation in Human Breast Cancer, Cancer Research, vol.65, issue.16, pp.7065-7070, 2005.
DOI : 10.1158/0008-5472.CAN-05-1783

V. Fulci, S. Chiaretti, M. Goldoni, G. Azzalin, N. Carucci et al., Quantitative technologies establish a novel microRNA profile of chronic lymphocytic leukemia, Blood, vol.109, issue.11, pp.4944-4951, 2007.
DOI : 10.1182/blood-2006-12-062398

P. Medina, M. Nolde, and F. Slack, OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma, Nature, vol.84, issue.7311, pp.86-90, 2010.
DOI : 10.1038/nature09284

M. Si, S. Zhu, H. Wu, Z. Lu, F. Wu et al., miR-21-mediated tumor growth, Oncogene, vol.1, issue.19, pp.2799-2803, 2007.
DOI : 10.1023/A:1021540120521

S. Zhu, H. Wu, F. Wu, D. Nie, S. Sheng et al., MicroRNA-21 targets tumor suppressor genes in invasion and metastasis, Cell Research, vol.60, issue.3, pp.350-359, 2008.
DOI : 10.1016/j.bbrc.2006.02.106

J. Cameron, C. Fewell, Q. Yin, J. Mcbride, X. Wang et al., Epstein???Barr virus growth/latency III program alters cellular microRNA expression, Virology, vol.382, issue.2, pp.257-266, 2008.
DOI : 10.1016/j.virol.2008.09.018
URL : http://doi.org/10.1016/j.virol.2008.09.018

I. Asangani, S. Rasheed, D. Nikolova, J. Leupold, N. Colburn et al., MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer, Oncogene, vol.62, issue.15, pp.2128-2136, 2008.
DOI : 10.1074/jbc.M611393200

D. Baek, J. Villon, C. Shin, F. Camargo, S. Gygi et al., The impact of microRNAs on protein output, Nature, vol.35, issue.7209, pp.64-71, 2008.
DOI : 10.1038/nature07242

M. Masucci, S. Torsteindottir, J. Colombani, C. Brautbar, E. Klein et al., Down-regulation of class I HLA antigens and of the Epstein-Barr virus-encoded latent membrane protein in Burkitt lymphoma lines., Proceedings of the National Academy of Sciences, vol.84, issue.13, pp.4567-4571, 1987.
DOI : 10.1073/pnas.84.13.4567

J. Hou, P. Wang, L. Lin, X. Liu, F. Ma et al., MicroRNA-146a Feedback Inhibits RIG-I-Dependent Type I IFN Production in Macrophages by Targeting TRAF6, IRAK1, and IRAK2, The Journal of Immunology, vol.183, issue.3, pp.2150-2158, 2009.
DOI : 10.4049/jimmunol.0900707

Y. Luo, X. Cui, H. Ni, X. Yuan, M. Guo et al., MicroRNA-146A contributes to a normal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins, Arthritis Rheum, vol.60, pp.1065-1075, 2009.

K. Kanda, B. Kempkes, G. Bornkamm, A. Von-gabain, and T. Decker, The Epstein-Barr virus nuclear antigen 2 (EBNA2), a protein required for B lymphocyte immortalization , induces the synthesis of type I interferon in Burkitt's lymphomacell lines, Biol Chem, vol.380, pp.213-221, 1999.

J. Hiscott, A. Wong, D. Alper, and S. Xanthoudakis, trans activation of type 1 interferon promoters by simian virus 40 T antigen., Molecular and Cellular Biology, vol.8, issue.8, pp.3397-3405, 1988.
DOI : 10.1128/MCB.8.8.3397

U. Nielsch, R. Pine, S. Zimmer, and L. Babiss, Induced expression of the endogenous beta interferon gene in adenovirus type 5-transformed rat fibroblasts, J Virol, vol.66, pp.1884-1890, 1992.

K. Kanda, T. Decker, P. Aman, M. Wahlstrom, A. Von-gabain et al., The EBNA2-related resistance towards alpha interferon (IFN-alpha) in Burkitt's lymphoma cells effects induction of IFN-induced genes but not the activation of transcription factor ISGF-3., Molecular and Cellular Biology, vol.12, issue.11, pp.4930-4936, 1992.
DOI : 10.1128/MCB.12.11.4930

D. Bhaumik, G. Scott, S. Schokrpur, C. Patil, J. Campisi et al., Expression of microRNA-146 suppresses NF-??B activity with reduction of metastatic potential in breast cancer cells, Oncogene, vol.9, issue.42, pp.5643-5647, 2008.
DOI : 10.1677/erc.1.00977