A. Schöpfer and . Boveris, Nitric oxide inhibits electron transfer and increases superoxide radical production in rat heart mitochondria and submitochondrial particles, Archives of Biochemistry and Biophysics, vol.328, issue.1, pp.85-92, 1996.

S. Moncada and J. D. Erusalimsky, OPINIONDoes nitric oxide modulate mitochondrial energy generation and apoptosis?, Nature Reviews Molecular Cell Biology, vol.3, issue.3, pp.214-220, 2002.
DOI : 10.1038/nrm762

F. Blandini, K. H. Braunewell, D. Manahan-vaughan, F. Orzi, and P. Sarti, Neurodegeneration and energy metabolism: from chemistry to clinics, Cell Death and Differentiation, vol.11, issue.4, pp.479-484, 2004.
DOI : 10.1038/sj.cdd.4401323

S. Shiva, J. Y. Oh, and A. L. Landar, Nitroxia: the pathological consequence of dysfunction in the nitric oxide

C. E. Cooper and C. Giulivi, Nitric oxide regulation of mitochondrial oxygen consumption II: molecular mechanism and tissue physiology, AJP: Cell Physiology, vol.292, issue.6, pp.1993-2003, 2007.
DOI : 10.1152/ajpcell.00310.2006

J. D. Erusalimsky and S. Moncada, Nitric Oxide and Mitochondrial Signaling: From Physiology to Pathophysiology, Arteriosclerosis, Thrombosis, and Vascular Biology, vol.27, issue.12, pp.2524-2531, 2007.
DOI : 10.1161/ATVBAHA.107.151167

P. Rt-i, A. Ffrè, M. C. B-a-r-o-n-e, E. Rt-e, and D. M. Brunori, Nitric oxide and cytochrome oxidase: reaction mechanisms from the enzyme to the cell, Free Radical Biology and Medicine, vol.34, issue.5, pp.509-520, 2003.

C. E. Cooper and G. C. Brown, The inhibition of mitochondrial cytochrome oxidase by the gases carbon monoxide, nitric oxide, hydrogen cyanide and hydrogen sulfide: chemical mechanism and physiological significance, Journal of Bioenergetics and Biomembranes, vol.21, issue.Suppl, pp.533-539, 2008.
DOI : 10.1007/s10863-008-9166-6

A. Galkin and S. Moncada, S-Nitrosation of Mitochondrial Complex I Depends on Its Structural Conformation, Journal of Biological Chemistry, vol.282, issue.52, pp.37448-37453, 2007.
DOI : 10.1074/jbc.M707543200

E. Clementi, G. C. Brown, M. Feelisch, and S. Moncada, Persistent inhibition of cell respiration by nitric oxide: Crucial role of S-nitrosylation of mitochondrial complex I and protective action of glutathione, Proceedings of the National Academy of Sciences, vol.95, issue.13, pp.7631-7636, 1998.
DOI : 10.1073/pnas.95.13.7631

C. E. Cooper, N. A. Davies, and M. Psychoulis, Nitric oxide and peroxynitrite cause irreversible increases in the Km for oxygen of mitochondrial cytochrome oxidase: in vitro and in vivo studies, Biochimica et Biophysica Acta (BBA) - Bioenergetics, vol.1607, issue.1, pp.27-34, 2003.
DOI : 10.1016/j.bbabio.2003.08.003

A. Giuffrè, P. Sarti, E. D. Itri, G. Buse, T. Soulimane et al., On the Mechanism of Inhibition of Cytochrome c Oxidase by Nitric Oxide, Journal of Biological Chemistry, vol.271, issue.52, pp.33404-33408, 1996.
DOI : 10.1074/jbc.271.52.33404

C. E. Cooper, Nitric oxide and cytochrome oxidase: substrate, inhibitor or effector?, Trends in Biochemical Sciences, vol.27, issue.1, pp.33-39, 2002.
DOI : 10.1016/S0968-0004(01)02035-7

F. Antunes, A. Boveris, and E. Cadenas, Oxidase, Antioxidants & Redox Signaling, vol.9, issue.10, pp.1569-1579, 2007.
DOI : 10.1089/ars.2007.1677

G. Benard, B. Faustin, and E. Passerieux, Physiological diversity of mitochondrial oxidative phosphorylation, AJP: Cell Physiology, vol.291, issue.6, pp.1172-1182, 2006.
DOI : 10.1152/ajpcell.00195.2006

Q. H. Gibson and C. Greenwood, Reactions of cytochrome oxidase with oxygen and carbon monoxide, Biochemical Journal, vol.86, issue.3, pp.541-554, 1963.
DOI : 10.1042/bj0860541

R. S. Blackmore, C. Greenwood, and Q. H. Gibson, Studies of the primary oxygen intermediate in the reaction of fully reduced cytochrome oxidase, Journal of Biological Chemistry, vol.266, issue.29, pp.19245-19249, 1991.

F. Malatesta, P. Sarti, G. Antonini, B. Vallone, M. Brunori et al., Electron transfer to the binuclear center in cytochrome oxidase: catalytic significance and evidence for an additional intermediate., Proceedings of the National Academy of Sciences, vol.87, issue.19, pp.7410-7413, 1990.
DOI : 10.1073/pnas.87.19.7410

M. B. Ru-no-ri, A. G-i-u-ffrè, E. D. Itri, and P. Sarti, Internal electron transfer in Cu-heme oxidases: thermodynamic or kinetic control, Journal of Biological Chemistry, vol.272, issue.32, pp.19870-19874, 1997.

P. Sarti, E. Forte, D. Mastronicola, A. Giuffrè, and M. Arese, Cytochrome c oxidase and nitric oxide in action: Molecular mechanisms and pathophysiological implications, Biochimica et Biophysica Acta (BBA) - Bioenergetics, vol.1817, issue.4, pp.610-619, 2012.
DOI : 10.1016/j.bbabio.2011.09.002

URL : https://hal.archives-ouvertes.fr/pasteur-00955450

D. C. Unitt, V. S. Hollis, M. Palacios-callender, N. Frakich, and S. Moncada, Inactivation of nitric oxide by cytochrome c oxidase under steady-state oxygen conditions, Biochimica et Biophysica Acta (BBA) - Bioenergetics, vol.1797, issue.3, pp.371-377, 2010.
DOI : 10.1016/j.bbabio.2009.12.002

B. Chance, C. Saronio, and J. S. Leigh, Functional intermediates in the reaction of membrane bound cytochrome oxidase with oxygen, Journal of Biological Chemistry, vol.250, issue.24, pp.9226-9237, 1975.

L. Weng and G. M. Baker, Reaction of hydrogen peroxide with the rapid form of resting cytochrome oxidase, Biochemistry, vol.30, issue.23, pp.5727-5733, 1991.
DOI : 10.1021/bi00237a014

M. Fabian, W. W. Wong, R. B. Gennis, and G. Palmer, Mass spectrometric determination of dioxygen bond splitting in the "peroxy" intermediate of cytochrome c oxidase, Proceedings of the National Academy of Sciences, vol.96, issue.23, pp.13114-13117, 1999.
DOI : 10.1073/pnas.96.23.13114

S. Han, Y. C. Ching, and D. L. Rousseau, Ferryl and hydroxy intermediates in the reaction of oxygen with reduced cytochrome c oxidase, Nature, vol.235, issue.6296, pp.89-90, 1990.
DOI : 10.1021/bi00575a019

P. Sarti, A. Giuffrè, E. Forte, D. Mastronicola, M. C. Barone et al., Nitric Oxide and Cytochrome c Oxidase: Mechanisms of Inhibition and NO Degradation, Biochemical and Biophysical Research Communications, vol.274, issue.1, pp.183-187, 2000.
DOI : 10.1006/bbrc.2000.3117

G. Stubauer, A. Giuffrè, M. Brunori, and P. Sarti, Cytochrome c Oxidase Does Not Catalyze the Anaerobic Reduction of NO, Biochemical and Biophysical Research Communications, vol.245, issue.2, pp.459-465, 1998.
DOI : 10.1006/bbrc.1998.8457

J. Torres, V. Darley-usmar, and M. T. Wilson, Inhibition of cytochrome c oxidase in turnover by nitric oxide: mechanism and implications for control of respiration, Biochemical Journal, vol.312, issue.1, pp.169-173, 1995.
DOI : 10.1042/bj3120169

M. G. Mason, P. Nicholls, M. T. Wilson, and C. E. Cooper, Nitric oxide inhibition of respiration involves both competitive (heme) and noncompetitive (copper) binding to cytochrome c oxidase, Proceedings of the National Academy of Sciences, vol.103, issue.3, pp.708-713, 2006.
DOI : 10.1073/pnas.0506562103

D. Mastronicola, E. Arcuri, and M. Arese, Morphine but not fentanyl and methadone affects mitochondrial membrane potential by inducing nitric oxide release in glioma cells, Cellular and Molecular Life Sciences, vol.61, issue.23, pp.2991-2997, 2004.
DOI : 10.1007/s00018-004-4371-x

A. Giuffrè, G. Stubauer, and P. Sarti, The heme-copper oxidases of Thermus thermophilus catalyze the reduction of 10 oxide: evolutionary implications, International Journal of Cell Biology nitric Proceedings of the National Academy of Sciences of the United States of America, vol.96, issue.26, pp.14718-14723, 1999.

E. Forte, A. Urbani, M. Saraste, P. Sarti, M. Brunori et al., displays nitric oxide reductase activity, European Journal of Biochemistry, vol.262, issue.24, pp.6486-6491, 2001.
DOI : 10.1046/j.0014-2956.2001.02597.x

C. S. Butler, E. Forte, and F. M. Scandurra, Cytochrome bo3 from Escherichia coli: the binding and turnover of nitric oxide, Biochemical and Biophysical Research Communications, vol.296, issue.5, pp.1272-1278, 2002.
DOI : 10.1016/S0006-291X(02)02074-0

D. Mastronicola, M. L. Genova, and M. Arese, Control of respiration by nitric oxide in Keilin-Hartree particles, mitochondria and SH-SY5Y neuroblastoma cells, Cellular and Molecular Life Sciences (CMLS), vol.60, issue.8, pp.1752-1759, 2003.
DOI : 10.1007/s00018-003-3127-3

A. Giuffrè, M. C. Barone, and M. Brunori, Nitric Oxide Reacts with the Single-electron Reduced Active Site of Cytochrome c Oxidase, Journal of Biological Chemistry, vol.277, issue.25, pp.22402-22406, 2002.
DOI : 10.1074/jbc.M201514200

C. E. Cooper, M. G. Mason, and . Nicholls, A dynamic model of nitric oxide inhibition of mitochondrial cytochrome c oxidase, Biochimica et Biophysica Acta (BBA) - Bioenergetics, vol.1777, issue.7-8, pp.867-876, 2008.
DOI : 10.1016/j.bbabio.2008.03.021

G. W. Brudvig, T. H. Stevens, and S. I. Chan, Reactions of nitric oxide with cytochrome c oxidase, Biochemistry, vol.19, issue.23, pp.5275-5285, 1980.
DOI : 10.1021/bi00564a020

C. E. Cooper, J. Torres, M. A. Sharpe, and M. T. Wilson, Nitric oxide ejects electrons from the binuclear centre of cytochrome c oxidase by reacting with oxidised copper: a general mechanism for the interaction of copper proteins with nitric oxide, The FEBS Letters, vol.414, issue.2, pp.281-284, 1997.

A. Giuffrè, G. Stubauer, M. Brunori, P. Sarti, J. Torres et al., Chloride Bound to Oxidized Cytochrome c Oxidase Controls the Reaction with Nitric Oxide, Journal of Biological Chemistry, vol.273, issue.49, pp.32475-32478, 1998.
DOI : 10.1074/jbc.273.49.32475

E. Antonini, M. Brunori, and A. Colosimo, Oxygen "pulsed" cytochrome c oxidase: functional properties and catalytic relevance., Proceedings of the National Academy of Sciences, vol.74, issue.8, pp.3128-3132, 1977.
DOI : 10.1073/pnas.74.8.3128

J. Torres, M. A. Sharpe, A. Rosquist, C. E. Cooper, and M. T. Wilson, oxidase rapidly metabolises nitric oxide to nitrite, FEBS Letters, vol.315, issue.3, pp.263-266, 2000.
DOI : 10.1016/S0014-5793(00)01682-3

C. Giulivi, Characterization and function of mitochondrial nitric-oxide synthase, Free Radical Biology and Medicine, vol.34, issue.4, pp.397-408, 2003.
DOI : 10.1016/S0891-5849(02)01298-4

L. L. Pearce, A. J. Kanai, L. A. Birder, B. R. Pitt, and J. Peterson, The Catabolic Fate of Nitric Oxide, Journal of Biological Chemistry, vol.277, issue.16, pp.13556-13562, 2002.
DOI : 10.1074/jbc.M109838200

G. Sgarbi, A. Baracca, G. Lenaz, L. M. Valentino, V. Carelli et al., Inefficient coupling between proton transport and ATP synthesis may be the pathogenic mechanism for NARP and Leigh syndrome resulting from the T8993G mutation in mtDNA, Biochemical Journal, vol.395, issue.3, pp.493-500, 2006.
DOI : 10.1042/BJ20051748

M. Arese, M. C. Magnifico, and D. Mastronicola, Nanomolar melatonin enhances nNOS expression and controls HaCaT-cells bioenergetics, IUBMB Life, vol.98, issue.3, pp.251-258, 2004.
DOI : 10.1002/iub.603

A. Giuffrè, E. Forte, M. Brunori, and P. Sarti, oxidase and myoglobin: Competition and reaction pathways, FEBS Letters, vol.34, issue.11, pp.2528-2532, 2005.
DOI : 10.1016/j.febslet.2005.03.067

V. B. Borisov, E. Forte, A. Giuffrè, A. Konstantinov, and P. Sarti, Reaction of nitric oxide with the oxidized di-heme and heme???copper oxygen-reducing centers of terminal oxidases: Different reaction pathways and end-products, Journal of Inorganic Biochemistry, vol.103, issue.8, pp.1185-1187, 2009.
DOI : 10.1016/j.jinorgbio.2009.06.002

V. B. Borisov, E. Forte, A. A. Konstantinov, R. K. Poole, P. Sarti et al., with nitric oxide, FEBS Letters, vol.124, issue.1-2, pp.201-204, 2004.
DOI : 10.1016/j.febslet.2004.09.013

V. B. Borisov, E. Forte, P. Sarti, M. Brunori, A. A. Konstantinov et al., Redox control of fast ligand dissociation from Escherichia coli cytochrome bd, Biochemical and Biophysical Research Communications, vol.355, issue.1, pp.97-102, 2007.
DOI : 10.1016/j.bbrc.2007.01.118

S. Rinaldo, K. A. Sam, and N. Castiglione, nitrite reductases, Biochemical Journal, vol.183, issue.1, pp.217-225, 2011.
DOI : 10.1074/jbc.M005033200

URL : https://hal.archives-ouvertes.fr/pasteur-00952182

M. G. Mason, P. Nicholls, and C. E. Cooper, oxidase: redox interactions between metal centres, Biochemical Journal, vol.110, issue.2, pp.237-246, 2009.
DOI : 10.1021/bi00042a011

URL : https://hal.archives-ouvertes.fr/hal-00479128

A. Giuffrè, V. B. Borisov, D. Mastronicola, P. Sarti, and E. Forte, oxidase and nitric oxide: From reaction mechanisms to bacterial physiology, FEBS Letters, vol.34, issue.5, pp.622-629, 2012.
DOI : 10.1016/j.febslet.2011.07.035

A. Masci, D. Mastronicola, and M. Arese, Control of cell respiration by nitric oxide in Ataxia Telangiectasia lymphoblastoid cells, Biochimica et Biophysica Acta (BBA) - Bioenergetics, vol.1777, issue.1, pp.66-73, 2008.
DOI : 10.1016/j.bbabio.2007.10.016

J. T. Orres, C. E. Cooper, and . Wilson, Acommonmechanism for the interaction of nitric oxide with the oxidized binuclear centre and oxygen intermediates of cytochrome c oxidase, Journal of Biological Chemistry, vol.273, issue.15, pp.8756-8766, 1998.

J. O. Lundberg, E. Weitzberg, and M. T. Gladwin, The nitrate???nitrite???nitric oxide pathway in physiology and therapeutics, Nature Reviews Drug Discovery, vol.336, issue.2, pp.156-167, 2008.
DOI : 10.1038/nrd2466

S. Shiva and M. T. Gladwin, Nitrite mediates cytoprotection after ischemia/reperfusion by modulating mitochondrial function, Basic Research in Cardiology, vol.83, issue.2, pp.113-119, 2009.
DOI : 10.1007/s00395-009-0009-3

A. Webb, R. Bond, P. Mclean, R. Uppal, N. Benjamin et al., Reduction of nitrite to nitric oxide during ischemia protects against myocardial ischemia-reperfusion damage, Proceedings of the National Academy of Sciences, vol.101, issue.37, pp.13683-13688, 2004.
DOI : 10.1073/pnas.0402927101

J. L. Zweier, A. Samouilov, and P. Kuppusamy, Non-enzymatic nitric oxide synthesis in biological systems, Biochimica et Biophysica Acta (BBA) - Bioenergetics, vol.1411, issue.2-3, pp.250-262, 1999.
DOI : 10.1016/S0005-2728(99)00018-3

A. R. Whorton, D. B. Simonds, and C. A. Piantadosi, Regulation of nitric oxide synthesis by oxygen in vascular endothelial cells, American Journal of Physiology, vol.272, issue.6, pp.1161-1166, 1997.

R. O. Poyton, P. R. Castello, K. A. Ball, and D. K. Pan, Mitochondria and Hypoxic Signaling, Annals of the New York Academy of Sciences, vol.283, issue.1, pp.48-56, 2009.
DOI : 10.1111/j.1749-6632.2009.05046.x

G. Stubauer, A. Giuffrè, and P. Sarti, Mechanism of S-Nitrosothiol Formation and Degradation Mediated by Copper Ions, Journal of Biological Chemistry, vol.274, issue.40, pp.28128-28133, 1999.
DOI : 10.1074/jbc.274.40.28128

E. N. Dedkova, X. Ji, S. L. Lipsius, and L. A. Blatter, Mitochondrial calcium uptake stimulates nitric oxide production in mitochondria of bovine vascular endothelial cells, AJP: Cell Physiology, vol.286, issue.2, pp.406-415, 2004.
DOI : 10.1152/ajpcell.00155.2003

G. C. Brown, Nitric oxide produced by activated astrocytes rapidly and reversibly inhibits cellular respiration, Neuroscience Letters, vol.193, issue.3, pp.201-204, 1995.
DOI : 10.1016/0304-3940(95)11703-Y

S. Mercadante, Managing Breakthrough Pain, Current Pain and Headache Reports, vol.13, issue.4, pp.244-249, 2011.
DOI : 10.1007/s11916-011-0191-5

G. E. Plante and T. B. Vanitallie, Opioids for cancer pain: the challenge of optimizing treatment, Metabolism, vol.59, pp.47-52, 2010.
DOI : 10.1016/j.metabol.2010.07.010

G. W. Pasternak, Y. A. Kolesnikov, and A. M. Babey, Perspectives on the N-Methyl-?-Aspartate/Nitric Oxide Cascade and Opioid Tolerance, Neuropsychopharmacology, vol.13, issue.4, pp.309-313, 1995.
DOI : 10.1016/0893-133X(95)00084-Q

J. Mark-quillan, K. W. Carlson, C. Song, D. Wang, and W. Sadée, Differential Effects of micro-Opioid Receptor Ligands on Ca2+ Signaling, Journal of Pharmacology and Experimental Therapeutics, vol.302, issue.3, pp.1002-1012, 2002.
DOI : 10.1124/jpet.302.3.1002

M. Reers, T. W. Smith, and L. B. Chen, J-aggregate formation of a carbocyanine as a quantitative fluorescent indicator of membrane potential, Biochemistry, vol.30, issue.18, pp.4480-4486, 1991.
DOI : 10.1021/bi00232a015

F. Luchetti, B. Canonico, and M. Betti, Melatonin signaling and cell protection function, The FASEB Journal, vol.24, issue.10, pp.3603-3624, 2010.
DOI : 10.1096/fj.10-154450

O. Warburg, On respiratory impairment in cancer cells, Science, vol.124, issue.3215, pp.269-270, 1956.

P. S. Brookes, D. W. Kraus, and S. Shiva, Control of Mitochondrial Respiration by NO., Effects of Low Oxygen and Respiratory State, Journal of Biological Chemistry, vol.278, issue.34, pp.31603-31609, 2003.
DOI : 10.1074/jbc.M211784200

V. Borutaité and G. C. Brown, Rapid reduction of nitric oxide by mitochondria, and reversible inhibition of mitochondrial respiration by nitric oxide, Biochemical Journal, vol.315, issue.1, pp.295-299, 1996.
DOI : 10.1042/bj3150295

M. Palacios-callender, V. Hollis, N. Frakich, J. Mateo, and S. Moncada, Cytochrome c oxidase maintains mitochondrial respiration during partial inhibition by nitric oxide, Journal of Cell Science, vol.120, issue.1, pp.160-165, 2007.
DOI : 10.1242/jcs.03308

M. Palacios-callender, V. Hollis, M. Mitchison, N. Frakich, D. Unitt et al., Cytochrome c oxidase regulates endogenous nitric oxide availability in respiring cells: A possible explanation for hypoxic vasodilation, Proceedings of the National Academy of Sciences, vol.104, issue.47, pp.18508-18513, 2007.
DOI : 10.1073/pnas.0709440104

B. Chance, Reaction of Oxygen with the Respiratory Chain in Cells and Tissues, The Journal of General Physiology, vol.49, issue.1, pp.163-195, 1965.
DOI : 10.1085/jgp.49.1.163

J. P. Mazat, R. Rossignol, M. Malgat, C. Rocher, B. Faustin et al., What do mitochondrial diseases teach us about normal mitochondrial functions... that we already knew: threshold expression of mitochondrial defects, Biochimica et Biophysica Acta (BBA) - Bioenergetics, vol.1504, issue.1, pp.20-30, 1999.
DOI : 10.1016/S0005-2728(00)00236-X

J. P. Bolaños, A. Almeida, and S. Moncada, Glycolysis: a bioenergetic or a survival pathway?, Trends in Biochemical Sciences, vol.35, issue.3, pp.145-149, 2010.
DOI : 10.1016/j.tibs.2009.10.006

A. M-e-i-d-a, J. M-e-i-d-a, J. P. , and S. Moncada, Different responses of astrocytes and neurons to nitric oxide: the role of glycolytically generated ATP in astrocyte protection, Proceedings of the National Academy of Sciences of the United States of America, vol.98, issue.26, pp.15294-15299, 2001.

F. Antunes, A. Boveris, and E. Cadenas, On the mechanism and biology of cytochrome oxidase inhibition by nitric oxide, Proceedings of the National Academy of Sciences, vol.101, issue.48, pp.16774-16779, 2004.
DOI : 10.1073/pnas.0405368101

M. S. Meyn, Ataxia-telangiectasia, cancer and the pathobiology of the ATM gene, Clinical Genetics, vol.78, issue.1, pp.289-304, 1999.
DOI : 10.1016/S0167-8140(98)00014-0

P. J. Mckinnon, ATM and ataxia telangiectasia, EMBO reports, vol.63, issue.8, pp.772-776, 2004.
DOI : 10.1016/S0092-8674(00)81174-5

K. Savitsky, S. Sfez, and D. A. Tagle, The complete sequence of the coding region of the ATM gene reveals similarity to cell cycle regulators in different species, Human Molecular Genetics, vol.4, issue.11, pp.2025-2032, 1995.
DOI : 10.1093/hmg/4.11.2025

G. Rotman and Y. Shiloh, ATM: from gene to function, Human Molecular Genetics, vol.7, issue.10, pp.1555-1563, 1998.
DOI : 10.1093/hmg/7.10.1555

M. F. Lavin and Y. Shiloh, THE GENETIC DEFECT IN ATAXIA-TELANGIECTASIA, Annual Review of Immunology, vol.15, issue.1, pp.177-202, 1997.
DOI : 10.1146/annurev.immunol.15.1.177

A. Barzilai, G. Rotman, and Y. Shiloh, ATM deficiency and oxidative stress: a new dimension of defective response to DNA damage, DNA Repair, vol.1, issue.1, pp.3-25, 2002.
DOI : 10.1016/S1568-7864(01)00007-6

R. Reliene, E. Fischer, and R. H. Schiestl, Effect of N-Acetyl Cysteine on Oxidative DNA Damage and the Frequency of DNA Deletions in Atm-Deficient Mice, Cancer Research, vol.64, issue.15, pp.5148-5153, 2004.
DOI : 10.1158/0008-5472.CAN-04-0442

C. Barlow, S. Hirotsune, and R. Paylor, Atm-Deficient Mice: A Paradigm of Ataxia Telangiectasia, Cell, vol.86, issue.1, pp.159-171, 1996.
DOI : 10.1016/S0092-8674(00)80086-0

Y. Xu, T. Ashley, E. E. Brainerd, R. T. Bronson, M. S. Meyn et al., Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma., Genes & Development, vol.10, issue.19, pp.2411-2422, 1996.
DOI : 10.1101/gad.10.19.2411

A. J. Bishop, C. Barlow, A. J. Wynshaw-boris, and R. H. Schiestl, Atm deficiency causes an increased frequency of intrachromosomal homologous recombination in mice, Cancer Research, vol.60, issue.2, pp.395-399, 2000.

J. Reichenbach, R. Schubert, D. Schindler, K. Müller, H. Böhles et al., Elevated Oxidative Stress in Patients with Ataxia Telangiectasia, Antioxidants & Redox Signaling, vol.4, issue.3, pp.465-469, 2002.
DOI : 10.1089/15230860260196254

Y. Aksoy, O. Sanal, and A. Metin, Antioxidant enzymes in red blood cells and lymphocytes of ataxia-telangiectasia patients, Turkish Journal of Pediatrics, vol.46, issue.3, pp.204-207, 2004.

M. Ambrose, J. V. Goldstine, and R. A. Gatti, Intrinsic mitochondrial dysfunction in ATM-deficient lymphoblastoid cells, Human Molecular Genetics, vol.16, issue.18, pp.2154-2164, 2007.
DOI : 10.1093/hmg/ddm166