Serum levels of IL-6 and TNF-alpha correlate with clinicopathological features and patient survival in patients with prostate cancer, Br J Cancer, vol.90, pp.2312-2316, 2004. ,
Inhibiting TNF-mediated signaling: a novel therapeutic paradigm for androgen independent prostate cancer, Apoptosis, vol.144, issue.2, pp.153-161, 2010. ,
DOI : 10.1007/s10495-009-0416-9
Caspase inhibitors, Cell Death and Differentiation, vol.6, issue.11, pp.1081-1086, 1999. ,
DOI : 10.1038/sj.cdd.4400594
FLIP-ping out: Death receptor signaling in the prostate, Cancer Biology & Therapy, vol.7, issue.8, pp.1171-1179, 2008. ,
DOI : 10.4161/cbt.7.8.6712
FLAME-1, a Novel FADD-like Anti-apoptotic Molecule That Regulates Fas/TNFR1-induced Apoptosis, Journal of Biological Chemistry, vol.272, issue.30, pp.18542-18545, 1997. ,
DOI : 10.1074/jbc.272.30.18542
Cellular FLICE-Like Inhibitory Protein (C-FLIP): A Novel Target for Cancer Therapy, Current Cancer Drug Targets, vol.8, issue.1, pp.37-46, 2008. ,
DOI : 10.2174/156800908783497087
An Inducible Pathway for Degradation of FLIP Protein Sensitizes Tumor Cells to TRAIL-induced Apoptosis, Journal of Biological Chemistry, vol.277, issue.25, pp.22320-22329, 2002. ,
DOI : 10.1074/jbc.M202458200
Rapid Turnover of c-FLIPshort Is Determined by Its Unique C-terminal Tail, Journal of Biological Chemistry, vol.280, issue.29, pp.27345-27355, 2005. ,
DOI : 10.1074/jbc.M504019200
A TNF- and c-Cbl-dependent FLIPS-degradation pathway and its function in Mycobacterium tuberculosis???induced macrophage apoptosis, Nature Immunology, vol.8, issue.8, pp.918-926, 2009. ,
DOI : 10.1038/ni.1754
c-Fos as a Proapoptotic Agent in TRAIL-Induced Apoptosis in Prostate Cancer Cells, Cancer Research, vol.67, issue.19, pp.9425-9434, 2007. ,
DOI : 10.1158/0008-5472.CAN-07-1310
FOXO3a mediates the androgen-dependent regulation of FLIP and contributes to TRAIL-induced apoptosis of LNCaP cells, Oncogene, vol.13, issue.32, pp.4422-4433, 2008. ,
DOI : 10.1158/0008-5472.CAN-04-1498
The Akt-regulated Forkhead Transcription Factor FOXO3a Controls Endothelial Cell Viability through Modulation of the Caspase-8 Inhibitor FLIP, Journal of Biological Chemistry, vol.279, issue.2, pp.1513-1525, 2004. ,
DOI : 10.1074/jbc.M304736200
Induction of FLIP expression by androgens protects prostate cancer cells from TRAIL-mediated apoptosis, The Prostate, vol.11, issue.10, pp.1696-1706, 2008. ,
DOI : 10.1002/pros.20844
Quantitative correlation between proteolysis and macro- and microautophagy in mouse hepatocytes during starvation and refeeding., Proceedings of the National Academy of Sciences, vol.80, issue.8, pp.2179-2183, 1983. ,
DOI : 10.1073/pnas.80.8.2179
Autophagy and the Integrated Stress Response, Molecular Cell, vol.40, issue.2, pp.280-293, 2010. ,
DOI : 10.1016/j.molcel.2010.09.023
Autophagy fights disease through cellular self-digestion, Nature, vol.120, issue.7182, pp.1069-1075, 2008. ,
DOI : 10.1038/nature06639
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670399
Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis, Cancer Cell, vol.10, issue.1, pp.51-64, 2006. ,
DOI : 10.1016/j.ccr.2006.06.001
URL : http://doi.org/10.1016/j.ccr.2006.06.001
Role of autophagy in cancer, Nature Reviews Cancer, vol.4, issue.12, pp.961-967, 2007. ,
DOI : 10.1038/nrc2254
Autophagy protects LNCaP cells under androgen deprivation conditions, Autophagy, vol.4, issue.1, pp.54-60, 2008. ,
DOI : 10.4161/auto.5209
AMPK-mediated autophagy is a survival mechanism in androgen-dependent prostate cancer cells subjected to androgen deprivation and hypoxia, Cellular Signalling, vol.23, issue.9, pp.1466-1472, 2011. ,
DOI : 10.1016/j.cellsig.2011.04.008
Chemical modulators of autophagy as biological probes and potential therapeutics, Nature Chemical Biology, vol.5, issue.1, pp.9-17, 2011. ,
DOI : 10.1038/nchembio.500
-7/IL-24), Autophagy, vol.7, issue.9, pp.24-31, 2011. ,
DOI : 10.4161/auto.7.9.16163
URL : https://hal.archives-ouvertes.fr/hal-01439629
Statin-induced autophagy by inhibition of geranylgeranyl biosynthesis in prostate cancer PC3 cells, The Prostate, vol.44, issue.15, pp.971-981, 2010. ,
DOI : 10.1002/pros.21131
Fisetin induces autophagic cell death through suppression of mTOR signaling pathway in prostate cancer cells, Carcinogenesis, vol.31, issue.8, pp.1424-1433, 2010. ,
DOI : 10.1093/carcin/bgq115
c-Flip overexpression reduces cardiac hypertrophy in response to pressure overload, Journal of Hypertension, vol.26, issue.5, pp.1008-1016, 2008. ,
DOI : 10.1097/HJH.0b013e3282f6a179
c-Flip overexpression affects satellite cell proliferation and promotes skeletal muscle aging, Cell Death and Disease, vol.3, issue.4, p.38, 2010. ,
DOI : 10.1038/cddis.2010.17
URL : http://doi.org/10.1038/cddis.2010.17
P38 MAPK protects against TNF-??-provoked apoptosis in LNCaP prostatic cancer cells, Apoptosis, vol.40, issue.11, pp.1969-1975, 2006. ,
DOI : 10.1007/s10495-006-0086-9
Autophagosomal I??B?? Degradation Plays a Role in the Long Term Control of Tumor Necrosis Factor-??-induced Nuclear Factor-??B (NF-??B) Activity, Journal of Biological Chemistry, vol.286, issue.26, pp.22886-22893, 2011. ,
DOI : 10.1074/jbc.M110.199950
Autophagy and cytokines, Cytokine, vol.56, issue.2, pp.140-144, 2011. ,
DOI : 10.1016/j.cyto.2011.08.022
URL : http://www.tara.tcd.ie/bitstream/2262/60055/1/Harris%202011.pdf
Reactive oxygen intermediates in TNF signaling, Molecular Immunology, vol.39, issue.9, pp.509-517, 2002. ,
DOI : 10.1016/S0161-5890(02)00207-9
The Fas Death Signaling Pathway Connecting Reactive Oxygen Species Generation and FLICE Inhibitory Protein Down-Regulation, The Journal of Immunology, vol.180, issue.5, pp.3072-3080, 2008. ,
DOI : 10.4049/jimmunol.180.5.3072
The E3 Ubiquitin Ligase Itch Couples JNK Activation to TNF??-induced Cell Death by Inducing c-FLIPL Turnover, Cell, vol.124, issue.3, pp.601-613, 2006. ,
DOI : 10.1016/j.cell.2006.01.021
Execution of Macrophage Apoptosis by Mycobacterium avium through Apoptosis Signal-regulating Kinase 1/p38 Mitogen-activated Protein Kinase Signaling and Caspase 8 Activation, Journal of Biological Chemistry, vol.278, issue.29, pp.26517-26525, 2003. ,
DOI : 10.1074/jbc.M300852200
Cryptotanshinone enhances TNF-??-induced apoptosis in chronic myeloid leukemia KBM-5 cells, Apoptosis, vol.11, issue.1, pp.696-707, 2011. ,
DOI : 10.1007/s10495-011-0605-1
Fucoidan Extract Induces Apoptosis in MCF-7 Cells via a Mechanism Involving the ROS-Dependent JNK Activation and Mitochondria-Mediated Pathways, PLoS ONE, vol.6, issue.11, p.27441, 2011. ,
DOI : 10.1371/journal.pone.0027441.g009
Deciphering the Role of Forkhead Transcription Factors in Cancer Therapy, Current Drug Targets, vol.12, issue.9, pp.1284-1290, 2011. ,
DOI : 10.2174/138945011796150299
Resveratrol Induces Growth Arrest and Apoptosis through Activation of FOXO Transcription Factors in Prostate Cancer Cells, PLoS ONE, vol.7, issue.12, p.15288, 2010. ,
DOI : 10.1371/journal.pone.0015288.g006
FOXO3A as a key molecule for all-trans retinoic acid-induced granulocytic differentiation and apoptosis in acute promyelocytic leukemia, Blood, vol.115, issue.18, pp.3787-3795, 2010. ,
DOI : 10.1182/blood-2009-05-222976
Autophagy delays apoptotic death in breast cancer cells following DNA damage, Cell Death and Differentiation, vol.109, issue.3, pp.500-510, 2007. ,
DOI : 10.1093/emboj/18.9.2330
Inhibition of Macroautophagy Triggers Apoptosis, Molecular and Cellular Biology, vol.25, issue.3, pp.1025-1040, 2005. ,
DOI : 10.1128/MCB.25.3.1025-1040.2005
Autophagy in Cancer: Good, Bad, or Both?, Cancer Research, vol.66, issue.19, pp.9349-9351, 2006. ,
DOI : 10.1158/0008-5472.CAN-06-1597
Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells, Cell Death and Differentiation, vol.11, issue.4, pp.448-457, 2004. ,
DOI : 10.1038/sj.cdd.4401359
Growth Factor Regulation of Autophagy and Cell Survival in the Absence of Apoptosis, Cell, vol.120, issue.2, pp.237-248, 2005. ,
DOI : 10.1016/j.cell.2004.11.046
HMGB1 as an autophagy sensor in oxidative stress, Autophagy, vol.7, issue.8, pp.904-906, 2011. ,
DOI : 10.4161/auto.7.8.15704
Tumour necrosis factor and cancer, Nature Reviews Cancer, vol.265, issue.5, pp.361-371, 2009. ,
DOI : 10.1038/nature01322
Effect of dual inhibition of apoptosis and autophagy in prostate cancer, The Prostate, vol.106, issue.8, pp.1374-1381, 2012. ,
DOI : 10.1002/pros.22487
Involvement of Protective Autophagy in TRAIL Resistance of Apoptosis-defective Tumor Cells, Journal of Biological Chemistry, vol.283, issue.28, pp.19665-19677, 2008. ,
DOI : 10.1074/jbc.M710169200
FLIP is expressed in mouse testis and protects germ cells from apoptosis, Cell Death and Differentiation, vol.10, issue.2, pp.175-184, 2003. ,
DOI : 10.1038/sj.cdd.4401137
c-Flip expression and function in fetal mouse gonocytes, The FASEB Journal, vol.19, p.124, 2005. ,
DOI : 10.1096/fj.05-4626fje
is expressed in undifferentiated mouse male germ cells, FEBS Letters, vol.72, issue.26, pp.6109-6114, 2006. ,
DOI : 10.1016/j.febslet.2006.10.010
Arsenic trioxide sensitizes promonocytic leukemia cells to TNF??-induced apoptosis via p38-MAPK-regulated activation of both receptor-mediated and mitochondrial pathways, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, vol.1773, issue.11, pp.1653-1663, 2007. ,
DOI : 10.1016/j.bbamcr.2007.06.003
RETRACTED: Identification of Phosphorylated p38 as a Novel DAPK-Interacting Partner during TNF??-Induced Apoptosis in Colorectal Tumor Cells, The American Journal of Pathology, vol.175, issue.2, pp.557-570, 2009. ,
DOI : 10.2353/ajpath.2009.080853
p38?? MAP Kinase as a Sensor of Reactive Oxygen Species in Tumorigenesis, Cancer Cell, vol.11, issue.2, pp.191-205, 2007. ,
DOI : 10.1016/j.ccr.2006.12.013
A Novel PTEN-Dependent Link to Ubiquitination Controls FLIPS Stability and TRAIL Sensitivity in Glioblastoma Multiforme, Cancer Research, vol.69, issue.20, pp.7911-7916, 2009. ,
DOI : 10.1158/0008-5472.CAN-09-1287
E1A Sensitizes Cells to Tumor Necrosis Factor Alpha by Downregulating c-FLIPS, Journal of Virology, vol.77, issue.4, pp.2651-2662, 2003. ,
DOI : 10.1128/JVI.77.4.2651-2662.2003
Proteasome inhibitors activate autophagy as a cytoprotective response in human prostate cancer cells, Oncogene, vol.3, issue.3, pp.451-462, 2010. ,
DOI : 10.1158/0008-5472.CAN-08-4103
Cytotoxic sensitivity to tumor necrosis factor-? in PC3 and LNCaP prostatic cancer cells is regulated by extracellular levels of SGP-2 (clusterin), The Prostate, vol.72, issue.2, pp.87-93, 1999. ,
DOI : 10.1002/(SICI)1097-0045(19990501)39:2<87::AID-PROS2>3.0.CO;2-Z
Cloning and Characterization of Three Human Forkhead Genes That Comprise an FKHR-like Gene Subfamily, Genomics, vol.47, issue.2, pp.187-199, 1998. ,
DOI : 10.1006/geno.1997.5122
Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor, Cell, vol.96, issue.6, pp.857-868, 1999. ,
DOI : 10.1016/S0092-8674(00)80595-4
Regulation of androgen receptor transcriptional activity by rapamycin in prostate cancer cell proliferation and survival, Oncogene, vol.280, issue.56, pp.7106-7117, 2008. ,
DOI : 10.1158/0008-5472.CAN-04-3137
Toll-like receptor 9-mediated inhibition of apoptosis occurs through suppression of FoxO3a activity and induction of FLIP expression, Experimental and Molecular Medicine, vol.247, issue.10, pp.712-720, 2010. ,
DOI : 10.3858/emm.2010.42.10.070
Expression of Human Prostatic Acid Phosphatase Correlates with Androgen-stimulated Cell Proliferation in Prostate Cancer Cell Lines, Journal of Biological Chemistry, vol.273, issue.10, pp.5939-5947, 1998. ,
DOI : 10.1074/jbc.273.10.5939
The Progression of LNCaP Human Prostate Cancer Cells to Androgen Independence Involves Decreased FOXO3a Expression and Reduced p27KIP1 Promoter Transactivation, Molecular Cancer Research, vol.3, issue.3, pp.163-169, 2005. ,
DOI : 10.1158/1541-7786.MCR-04-0163