Chromatin Modifications and Their Function, Cell, vol.128, issue.4, pp.693-705, 2007. ,
DOI : 10.1016/j.cell.2007.02.005
URL : http://doi.org/10.1016/j.cell.2007.02.005
Chromatin remodeling and cancer, part I: covalent histone modifications, Trends in Molecular Medicine, vol.13, issue.9, pp.13-363, 2007. ,
DOI : 10.1016/j.molmed.2007.07.003
Covalent histone modifications ??? miswritten, misinterpreted and mis-erased in human cancers, Nature Reviews Cancer, vol.21, issue.7, pp.457-469, 2010. ,
DOI : 10.1038/nrc2876
Epi-drugs to fight cancer: From chemistry to cancer treatment, the road ahead, The International Journal of Biochemistry & Cell Biology, vol.41, issue.1, p.41, 2009. ,
DOI : 10.1016/j.biocel.2008.08.020
Histone methyltransferases in cancer, Seminars in Cell & Developmental Biology, vol.21, issue.2, pp.209-220, 2010. ,
DOI : 10.1016/j.semcdb.2009.10.007
Small-molecule chromatin-modifying agents: therapeutic applications, Epigenomics, vol.2, issue.2, pp.307-324, 2010. ,
DOI : 10.2217/epi.10.7
Targeting Histone Demethylases: A New Avenue for the Fight against Cancer, Genes & Cancer, vol.2, issue.6, pp.663-679, 2011. ,
DOI : 10.1177/1947601911417976
Small Molecule Regulators of Protein Arginine Methyltransferases, Journal of Biological Chemistry, vol.279, issue.23, pp.279-23892, 2004. ,
DOI : 10.1074/jbc.M401853200
Small Molecule Inhibitors of Histone Arginine Methyltransferases:?? Homology Modeling, Molecular Docking, Binding Mode Analysis, and Biological Evaluations, Journal of Medicinal Chemistry, vol.50, issue.6, pp.50-1241, 2007. ,
DOI : 10.1021/jm061213n
Design, Synthesis and Biological Evaluation of Carboxy Analogues of Arginine Methyltransferase Inhibitor???1 (AMI-1), ChemMedChem, vol.25, issue.3, pp.398-414, 2010. ,
DOI : 10.1002/cmdc.200900459
Synthesis and Biological Validation of Novel Synthetic Histone/Protein Methyltransferase Inhibitors, ChemMedChem, vol.421, issue.7, pp.987-991, 2007. ,
DOI : 10.1002/cmdc.200700023
Cinnamoyl Compounds as Simple Molecules that Inhibit p300 Histone Acetyltransferase, Journal of Medicinal Chemistry, vol.50, issue.8, p.50, 2007. ,
DOI : 10.1021/jm060943s
Epigenetic Multiple Ligands: Mixed Histone/Protein Methyltransferase, Acetyltransferase, and Class III Deacetylase (Sirtuin) Inhibitors, Journal of Medicinal Chemistry, vol.51, issue.7, pp.51-2279, 2008. ,
DOI : 10.1021/jm701595q
Novel 3,5-Bis(bromohydroxybenzylidene)piperidin-4-ones as Coactivator-Associated Arginine Methyltransferase 1 Inhibitors: Enzyme Selectivity and Cellular Activity, Journal of Medicinal Chemistry, vol.54, issue.13, pp.5-54, 2011. ,
DOI : 10.1021/jm200453n
URL : https://hal.archives-ouvertes.fr/pasteur-00968654
PR-Set7 Is a Nucleosome-Specific Methyltransferase that Modifies Lysine 20 of Histone H4 and Is Associated with Silent Chromatin, Molecular Cell, vol.9, issue.6, pp.1201-1213, 2002. ,
DOI : 10.1016/S1097-2765(02)00548-8
A new regulator of the cell cycle, Cell Cycle, vol.283, issue.1, pp.68-72, 2011. ,
DOI : 10.1016/j.molcel.2007.07.012
Substrate Specificity and Kinetic Mechanism of Mammalian G9a Histone H3 Methyltransferase, Journal of Biological Chemistry, vol.279, issue.51, pp.279-53248, 2004. ,
DOI : 10.1074/jbc.M409604200
H3K9 Histone Methyltransferase G9a Promotes Lung Cancer Invasion and Metastasis by Silencing the Cell Adhesion Molecule Ep-CAM, H3K9 histone methyltransferase G9a promotes lung cancer invasion and metastasis by silencing the cell adhesion molecule Ep-CAM, pp.7830-7840, 2010. ,
DOI : 10.1158/0008-5472.CAN-10-0833
Set9, a novel histone H3 methyltransferase that facilitates transcription by precluding histone tail modifications required for heterochromatin formation Role of the histone H3 lysine 4 methyltransferase, SET7/9, in the regulation of NF-kappaB-dependent inflammatory genes. Relevance to diabetes and inflammation, Genes Dev. J. Biol. Chem, vol.16, issue.283, pp.26771-26781, 2002. ,
Polycomb Group Proteins Set the Stage for Early Lineage Commitment, Cell Stem Cell, vol.7, issue.3, pp.288-298, 2010. ,
DOI : 10.1016/j.stem.2010.08.004
Polycomb Group Proteins: Multi-Faceted Regulators of Somatic Stem Cells and Cancer, Cell Stem Cell, vol.7, issue.3, pp.299-313, 2010. ,
DOI : 10.1016/j.stem.2010.08.002
Epigenetic regulation of signaling pathways in cancer: Role of the histone methyltransferase EZH2, Journal of Gastroenterology and Hepatology, vol.112, issue.1, p.26, 2011. ,
DOI : 10.1111/j.1440-1746.2010.06447.x
EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells, Proc. Natl. Acad. Sci. U.S.A, p.100, 2003. ,
DOI : 10.1073/pnas.1933744100
The polycomb group protein EZH2 is involved in progression of prostate cancer, Nature, vol.159, issue.6907, pp.624-629, 2002. ,
DOI : 10.1074/jbc.M107795200
A Polycomb Repression Signature in Metastatic Prostate Cancer Predicts Cancer Outcome, Cancer Research, vol.67, issue.22, 2007. ,
DOI : 10.1158/0008-5472.CAN-07-2498
EZH2 is a mediator of EWS/FLI1 driven tumor growth and metastasis blocking endothelial and neuro-ectodermal differentiation, Proc. Natl. Acad. Sci. U.S.A. 106, pp.5324-5329, 2009. ,
DOI : 10.1073/pnas.0810759106
Epigenetic-Mediated Dysfunction of the Bone Morphogenetic Protein Pathway Inhibits Differentiation of Glioblastoma-Initiating Cells, Cancer Cell, vol.13, issue.1, pp.69-80, 2008. ,
DOI : 10.1016/j.ccr.2007.12.005
EZH2 Mediates Epigenetic Silencing of Neuroblastoma Suppressor Genes CASZ1, CLU, RUNX3, and NGFR, EZH2 mediates epigenetic silencing of neuroblastoma suppressor genes CASZ1, CLU, RUNX3 and NGFR, pp.315-324, 2012. ,
DOI : 10.1158/0008-5472.CAN-11-0961