J. W. Harper and S. J. Elledge, The DNA Damage Response: Ten Years After, Molecular Cell, vol.28, issue.5, pp.739-745, 2007.
DOI : 10.1016/j.molcel.2007.11.015

M. S. Huen and J. Chen, The DNA damage response pathways: at the crossroad of protein modifications, Cell Research, vol.4, issue.1, pp.8-16, 2008.
DOI : 10.1128/MCB.00579-07

M. Malanga and F. R. Althaus, The role of poly(ADP-ribose) in the DNA damage signaling network, Biochemistry and Cell Biology, vol.83, issue.3, pp.354-364, 2005.
DOI : 10.1139/o05-038

A. Hakme, H. K. Wong, F. Dantzer, and V. Schreiber, The expanding field of poly(ADPribosyl )ation reactionsProtein modifications: beyond the usual suspects' review series, pp.1094-1100, 2008.

D. D. 'amours, S. Desnoyers, I. D. Silva, and G. G. Poirier, Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions, Biochemical Journal, vol.342, issue.2, pp.249-268, 1999.
DOI : 10.1042/bj3420249

A. Burkle, Poly(ADP-ribose). The most elaborate metabolite of NAD+, FEBS Journal, vol.24, issue.21, pp.4576-4589, 2005.
DOI : 10.1016/S0960-9822(00)00752-1

P. O. Hassa and M. O. Hottiger, The diverse biological roles of mammalian PARPS, a small but powerful family of poly-ADP-ribose polymerases, Frontiers in Bioscience, vol.13, issue.13, pp.3046-3082, 2008.
DOI : 10.2741/2909

G. Gradwohl, J. M. Menissier-de-murcia, M. Molinete, F. Simonin, M. Koken et al., The second zinc-finger domain of poly(ADP-ribose) polymerase determines specificity for single-stranded breaks in DNA., Proceedings of the National Academy of Sciences, vol.87, issue.8, pp.2990-2994, 1990.
DOI : 10.1073/pnas.87.8.2990

P. L. Panzeter, C. A. Realini, and F. R. Althaus, Noncovalent interactions of poly(adenosine diphosphate ribose) with histones, Biochemistry, vol.31, issue.5, pp.1379-1385, 1992.
DOI : 10.1021/bi00120a014

J. P. Gagne, M. Isabelle, K. S. Lo, S. Bourassa, M. J. Hendzel et al., Proteome-wide identification of poly(ADP-ribose) binding proteins and poly(ADP-ribose)-associated protein complexes, Nucleic Acids Research, vol.36, issue.22, pp.6959-6976, 2008.
DOI : 10.1093/nar/gkn771
URL : https://hal.archives-ouvertes.fr/inserm-00353180

K. Sugimura, S. Takebayashi, H. Taguchi, S. Takeda, and K. Okumura, PARP-1 ensures regulation of replication fork progression by homologous recombination on damaged DNA, The Journal of Cell Biology, vol.18, issue.7, pp.1203-1212, 2008.
DOI : 10.1074/jbc.M402729200

H. E. Bryant, E. Petermann, N. Schultz, A. S. Jemth, O. Loseva et al., PARP is activated at stalled forks to mediate Mre11-dependent replication restart and recombination, The EMBO Journal, vol.268, issue.17, pp.2601-2615, 2009.
DOI : 10.1126/science.1083430

M. Audebert, B. Salles, and P. Calsou, Involvement of Poly(ADP-ribose) Polymerase-1 and XRCC1/DNA Ligase III in an Alternative Route for DNA Double-strand Breaks Rejoining, Journal of Biological Chemistry, vol.279, issue.53, pp.55117-55126, 2004.
DOI : 10.1074/jbc.M404524200

M. Wang, W. Wu, W. Wu, B. Rosidi, L. Zhang et al., PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways, Nucleic Acids Research, vol.34, issue.21, pp.6170-6182, 2006.
DOI : 10.1093/nar/gkl840

M. Kanai, K. Hanashiro, S. H. Kim, S. Hanai, A. H. Boulares et al., Inhibition of Crm1???p53 interaction and nuclear export of p53 by poly(ADP-ribosyl)ation, Nature Cell Biology, vol.6, issue.10, pp.1175-1183, 2007.
DOI : 10.1016/S0092-8674(03)00433-1

M. Malanga, J. M. Pleschke, H. E. Kleczkowska, and F. R. , Poly(ADP-ribose) Binds to Specific Domains of p53 and Alters Its DNA Binding Functions, Journal of Biological Chemistry, vol.273, issue.19, pp.11839-11843, 1998.
DOI : 10.1074/jbc.273.19.11839

J. M. Pleschke, H. E. Kleczkowska, M. Strohm, and F. R. , Poly(ADP-ribose) Binds to Specific Domains in DNA Damage Checkpoint Proteins, Journal of Biological Chemistry, vol.275, issue.52, pp.40974-40980, 2000.
DOI : 10.1074/jbc.M006520200

M. Stilmann, M. Hinz, S. C. Arslan, A. Zimmer, V. Schreiber et al., A nuclear poly(ADP-ribose)-dependent signalosome confers DNA damageinduced IkappaB kinase activation, Molecular Cell, pp.36-365, 2009.

Y. Shiloh, ATM and related protein kinases: safeguarding genome integrity, Nature Reviews Cancer, vol.12, issue.3, pp.155-168, 2003.
DOI : 10.1038/nrc1011

A. A. Goodarzi and S. P. Lees-miller, Biochemical characterization of the ataxia-telangiectasia mutated (ATM) protein from human cells, DNA Repair, vol.3, issue.7, pp.753-767, 2004.
DOI : 10.1016/j.dnarep.2004.03.041

F. Watanabe, H. Fukazawa, M. Masutani, H. Suzuki, H. Teraoka et al., Poly(ADP-ribose) polymerase-1 inhibits ATM kinase activity in DNA damage response, Biochemical and Biophysical Research Communications, vol.319, issue.2, pp.596-602, 2004.
DOI : 10.1016/j.bbrc.2004.05.031

R. Aguilar-quesada, J. A. Munoz-gamez, D. Martin-oliva, A. Peralta, M. T. Valenzuela et al., Interaction between ATM and PARP-1 in response to DNA damage and sensitization of ATM deficient cells through PARP inhibition, BMC Molecular Biology, vol.8, issue.1, 2007.
DOI : 10.1186/1471-2199-8-29

J. F. Haince, S. Kozlov, V. L. Dawson, T. M. Dawson, M. J. Hendzel et al., Ataxia Telangiectasia Mutated (ATM) Signaling Network Is Modulated by a Novel Poly(ADP-ribose)-dependent Pathway in the Early Response to DNA-damaging Agents, Journal of Biological Chemistry, vol.282, issue.22, pp.16441-16453, 2007.
DOI : 10.1074/jbc.M608406200

T. Bruno, F. De-nicola, S. Iezzi, D. Lecis, C. D. Angelo et al., Che-1 phosphorylation by ATM/ATR and Chk2 kinases activates p53 transcription and the G2/M checkpoint, Che-1 phosphorylation by ATM/ATR and Chk2 kinases activates p53 transcription and the G2/M checkpoint, pp.473-486, 2006.
DOI : 10.1016/j.ccr.2006.10.012

M. Fanciulli, T. Bruno, M. D. Padova, R. De-angelis, S. Iezzi et al., Identification of a novel partner of RNA polymerase II subunit 11, Che-1, which interacts with and affects the growth suppression function of Rb, FASEB Journal, pp.14-904, 2000.

Z. Q. Wang, B. Auer, L. Stingl, H. Berghammer, D. Haidacher et al., Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease., Genes & Development, vol.9, issue.5, pp.509-520, 1995.
DOI : 10.1101/gad.9.5.509

O. Cohausz, C. Blenn, M. Malanga, and F. R. Althaus, The roles of poly(ADP-ribose)-metabolizing enzymes in alkylation-induced cell death, Cellular and Molecular Life Sciences, vol.65, issue.4, pp.644-655, 2008.
DOI : 10.1007/s00018-008-7516-5

A. Reale, G. D. Matteis, G. Galleazzi, M. Zampieri, and P. Caiafa, Modulation of DNMT1 activity by ADP-ribose polymers, Oncogene, vol.24, issue.1, pp.13-19, 2005.
DOI : 10.1038/sj.onc.1208005

M. Zampieri, C. Passananti, R. Calabrese, M. Perilli, N. Corbi et al., Parp1 Localizes within the Dnmt1 Promoter and Protects Its Unmethylated State by Its Enzymatic Activity, Parp1 localizes within the Dnmt1 promoter and protects its unmethylated state by its enzymatic activity, p.4717, 2009.
DOI : 10.1371/journal.pone.0004717.s003

F. De-nicola, T. Bruno, S. Iezzi, M. D. Padova, A. Floridi et al., The Prolyl Isomerase Pin1 Affects Che-1 Stability in Response to Apoptotic DNA Damage, Journal of Biological Chemistry, vol.282, issue.27, pp.19685-19691, 2007.
DOI : 10.1074/jbc.M610282200

M. J. Carrozza, D. F. Stefanick, J. K. Horton, P. S. Kedar, and S. H. Wilson, PARP inhibition during alkylation-induced genotoxic stress signals a cell cycle checkpoint response mediated by ATM, DNA Repair, vol.8, issue.11, pp.1264-1272, 2009.
DOI : 10.1016/j.dnarep.2009.07.010

J. K. Horton, D. F. Stefanick, J. M. Naron, P. S. Kedar, and S. H. Wilson, Poly(ADP-ribose) Polymerase Activity Prevents Signaling Pathways for Cell Cycle Arrest after DNA Methylating Agent Exposure, Journal of Biological Chemistry, vol.280, issue.16, pp.15773-15785, 2005.
DOI : 10.1074/jbc.M413841200

G. Page, I. Lödige, D. Kögel, and K. H. Scheidtmann, AATF, a novel transcription factor that interacts with Dlk/ZIP kinase and interferes with apoptosis, FEBS Letters, pp.462-187, 1999.

S. Wieler, J. P. Gagne, H. Vaziri, G. G. Poirier, and S. Benchimol, Poly(ADP-ribose) Polymerase-1 Is a Positive Regulator of the p53-mediated G1 Arrest Response following Ionizing Radiation, Journal of Biological Chemistry, vol.278, issue.21, pp.18914-18921, 2003.
DOI : 10.1074/jbc.M211641200

D. L. Madison and J. R. Lundblad, C-terminal binding protein and poly(ADP)ribose polymerase 1 contribute to repression of the p21waf1/cip1 promoter, Oncogene, vol.19, issue.45, pp.6027-6039, 2010.
DOI : 10.1016/S1097-2765(00)00075-7

M. Tavassoli, M. H. Tavassoli, and S. Shall, Effect of DNA intercalators on poly(ADP-ribose) glycohydrolase activity, Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, vol.827, issue.3, pp.228-234, 1985.
DOI : 10.1016/0167-4838(85)90207-9

I. Ahel, D. Ahel, T. Matsusaka, A. J. Clark, J. Pines et al., Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins, Nature, vol.22, issue.7174, pp.81-85, 2008.
DOI : 10.1038/nature06420

D. Ahel, Z. Horejsi, N. Wiechens, S. E. Polo, E. Garcia-wilson et al., Poly(ADP-ribose)-Dependent Regulation of DNA Repair by the Chromatin Remodeling Enzyme ALC1, Science, vol.325, issue.5945, pp.325-1240, 2009.
DOI : 10.1126/science.1177321

A. J. Gottschalk, G. Timinszky, S. E. Kong, J. Jin, Y. Cai et al., Poly(ADPribosyl )ation directs recruitment and activation of an ATP-dependent chromatin remodeler, Proceedings of the National Academy of Sciences of the United States of America, pp.13770-13774, 2009.

G. Timinszky, S. Till, P. O. Hassa, M. Hothorn, G. Kustatscher et al., A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation, Nature Structural & Molecular Biology, vol.287, issue.9, pp.923-929, 2009.
DOI : 10.1093/nar/gkm216

V. S. Meder, M. Boeglin, G. De-murcia, and V. Schreiber, PARP-1 and PARP-2 interact with nucleophosmin/B23 and accumulate in transcriptionally active nucleoli, Journal of Cell Science, vol.118, issue.1, pp.211-222, 2005.
DOI : 10.1242/jcs.01606
URL : https://hal.archives-ouvertes.fr/hal-00192787

A. Rancourt and M. S. Satoh, Delocalization of nucleolar poly(ADP-ribose) polymerase-1 to the nucleoplasm and its novel link to cellular sensitivity to DNA damage, DNA Repair, vol.8, issue.3, pp.286-297, 2009.
DOI : 10.1016/j.dnarep.2008.11.018

J. S. Andersen, Y. W. Lam, A. K. Leung, S. E. Ong, C. E. Lyon et al., Nucleolar proteome dynamics, Nature, vol.6, issue.7021, pp.77-83, 2005.
DOI : 10.1091/mbc.E02-05-0271

T. Bruno, R. De-angelis, F. De-nicola, C. Barbato, M. D. Padova et al., Che-1 affects cell growth by interfering with the recruitment of HDAC1 by Rb, Cancer Cell, vol.2, issue.5, pp.387-399, 2002.
DOI : 10.1016/S1535-6108(02)00182-4

W. L. Kraus and J. T. Lis, PARP Goes Transcription, Cell, vol.113, issue.6, pp.677-683, 2003.
DOI : 10.1016/S0092-8674(03)00433-1
URL : http://doi.org/10.1016/s0092-8674(03)00433-1

G. Dellaire, D. P. Bazett, and -. , Beyond Repair Foci: Subnuclear Domains and the Cellular Response to DNA Damage, Cell Cycle, vol.6, issue.15, pp.1864-1872, 2007.
DOI : 10.4161/cc.6.15.4560

T. M. Yung, S. Sato, and M. S. Satoh, Poly(ADP-ribosyl)ation as a DNA Damage-induced Post-translational Modification Regulating Poly(ADP-ribose) Polymerase-1-Topoisomerase I Interaction, Journal of Biological Chemistry, vol.279, issue.38, pp.39686-39696, 2004.
DOI : 10.1074/jbc.M402729200

S. L. Oei, J. Griesenbeck, M. Schweiger, V. Babich, A. Kropotov et al., Interaction of the Transcription Factor YY1 with Human Poly(ADP-Ribosyl) Transferase, Biochemical and Biophysical Research Communications, vol.240, issue.1, pp.108-111, 1997.
DOI : 10.1006/bbrc.1997.7621

J. Won, S. Y. Chung, S. B. Kim, B. H. Byun, Y. S. Yoon et al., Dose-dependent UV stabilization of p53 in cultured human cells undergoing apoptosis is mediated by poly(ADP-ribosyl)ation, Molecules and Cells, vol.21, pp.218-223, 2006.

B. Catalgol, B. Wendt, S. Grimm, N. Breusing, N. K. Ozer et al., Chromatin repair after oxidative stress: Role of PARP-mediated proteasome activation, Free Radical Biology and Medicine, vol.48, issue.5, 2009.
DOI : 10.1016/j.freeradbiomed.2009.12.010

P. Mayer-kuckuk, O. Ullrich, M. Ziegler, T. Grune, and M. Schweiger, Functional Interaction of Poly(ADP-ribose) with the 20S Proteasome in Vitro, Biochemical and Biophysical Research Communications, vol.259, issue.3, pp.576-581, 1999.
DOI : 10.1006/bbrc.1999.0824

H. E. Bryant, N. Schultz, H. D. Thomas, K. M. Parker, D. Flower et al., Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase, Nature, vol.20, issue.7035, pp.913-917, 2005.
DOI : 10.1016/S0022-2836(03)00313-9

P. C. Fong, D. S. Boss, T. A. Yap, A. Tutt, P. Wu et al., Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers, pp.361-123, 2009.

T. Helleday, E. Petermann, C. Lundin, B. Hodgson, and R. A. Sharma, DNA repair pathways as targets for cancer therapy, Nature Reviews Cancer, vol.265, issue.3, pp.193-204, 2008.
DOI : 10.1038/nrc2342

M. Rouleau, A. Patel, M. J. Hendzel, S. H. Kaufmann, and G. G. Poirier, PARP inhibition: PARP1 and beyond, Nature Reviews Cancer, vol.52, issue.4, pp.293-301, 2010.
DOI : 10.1038/nrc2812
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910902