Epithelial-Mesenchymal Transitions in Development and Disease, Cell, vol.139, issue.5, pp.871-890, 2009. ,
DOI : 10.1016/j.cell.2009.11.007
The transcription factor Snail controls epithelial???mesenchymal transitions by repressing E-cadherin expression, Nature Cell Biology, vol.51, issue.2, pp.76-83, 2000. ,
DOI : 10.1006/dbio.1998.9047
The SLUG zinc-finger protein represses E-cadherin in breast cancer, Cancer Res, vol.62, pp.1613-1618, 2002. ,
The Snail genes as inducers of cell movement and survival: implications in development and cancer, Development, vol.132, issue.14, pp.3151-3161, 2005. ,
DOI : 10.1242/dev.01907
Epithelial-to-mesenchymal transitions in the liver, Hepatology, vol.135, issue.Suppl 1, pp.2007-2013, 2009. ,
DOI : 10.1002/hep.23196
Snail controls differentiation of hepatocytes by repressing HNF4?? expression, Journal of Cellular Physiology, vol.98, issue.1, pp.230-238, 2006. ,
DOI : 10.1002/jcp.20730
TGF??-induced EMT requires focal adhesion kinase (FAK) signaling, Experimental Cell Research, vol.314, issue.1, pp.143-152, 2008. ,
DOI : 10.1016/j.yexcr.2007.09.005
Transforming Growth Factor-beta1 Induces an Epithelial-to-Mesenchymal Transition State in Mouse Hepatocytes in Vitro, Journal of Biological Chemistry, vol.282, issue.30, pp.22089-22101, 2007. ,
DOI : 10.1074/jbc.M700998200
Evidence for epithelial-mesenchymal transitions in adult liver cells, AJP: Gastrointestinal and Liver Physiology, vol.291, issue.4, pp.575-583, 2006. ,
DOI : 10.1152/ajpgi.00102.2006
Hepatocyte nuclear factor 4?? orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver, Proceedings of the National Academy of Sciences, vol.103, issue.22, pp.8419-8424, 2006. ,
DOI : 10.1073/pnas.0600246103
Hepatocyte nuclear factor 4?? controls the development of a hepatic epithelium and liver morphogenesis, Nature Genetics, vol.34, issue.3, pp.292-296, 2003. ,
DOI : 10.1038/ng1175
Progression of HCC in mice is associated with a downregulation in the expression of hepatocyte nuclear factors, Hepatology, vol.968, issue.4, pp.1038-1047, 2004. ,
DOI : 10.1002/hep.20155
Hepatocyte nuclear factor 4?? attenuates hepatic fibrosis in rats, Gut, vol.59, issue.2, pp.236-246, 2010. ,
DOI : 10.1136/gut.2008.174904
Hepatocyte Nuclear Factor 4?? (Nuclear Receptor 2A1) Is Essential for Maintenance of Hepatic Gene Expression and Lipid Homeostasis, Molecular and Cellular Biology, vol.21, issue.4, pp.1393-1403, 2001. ,
DOI : 10.1128/MCB.21.4.1393-1403.2001
Convergence of Wnt Signaling on the HNF4??-Driven Transcription in Controlling Liver Zonation, Gastroenterology, vol.137, issue.2, pp.660-672, 2009. ,
DOI : 10.1053/j.gastro.2009.05.038
Hepatocyte Nuclear Factor 4 Provokes Expression of Epithelial Marker Genes, Acting As a Morphogen in Dedifferentiated Hepatoma Cells, The Journal of Cell Biology, vol.16, issue.4, pp.935-946, 1998. ,
DOI : 10.1073/pnas.89.19.9069
Expression of HNF4?? isoforms in mouse liver development is regulated by sequential promoter usage and constitutive 3??? end splicing, Mechanisms of Development, vol.109, issue.2, pp.183-193, 2001. ,
DOI : 10.1016/S0925-4773(01)00521-4
Transforming Growth Factor ??-1 Induces Snail Transcription Factor in Epithelial Cell Lines, Journal of Biological Chemistry, vol.278, issue.23, pp.21113-21123, 2003. ,
DOI : 10.1074/jbc.M211304200
The transcription factor Snail is a repressor of E-cadherin gene expression in epithelial tumour cells, Nature Cell Biology, vol.17, issue.2, pp.84-89, 2000. ,
DOI : 10.1083/jcb.111.3.1265
Transgenic expression in the liver of truncated Met blocks apoptosis and permits immortalization of hepatocytes, The EMBO Journal, vol.16, issue.3, pp.495-503, 1997. ,
DOI : 10.1093/emboj/16.3.495
A transcriptional hierarchy involved in mammalian cell-type
specification, Nature, vol.355, issue.6359, pp.457-461, 1992. ,
DOI : 10.1038/355457a0
Hepatocyte Nuclear Factor 4?? enhances the Hepatocyte Nuclear Factor 1??-mediated activation of transcription, Nucleic Acids Research, vol.32, issue.8, pp.2586-2593, 2004. ,
DOI : 10.1093/nar/gkh581
Mechanisms of mutual functional interactions between HNF-4alpha and HNF-1alpha revealed by mutations that cause maturity onset diabetes of the young ,
Control of Pancreas and Liver Gene Expression by HNF Transcription Factors, Science, vol.303, issue.5662, pp.1378-1381, 2004. ,
DOI : 10.1126/science.1089769
Transforming growth factor-?? employs HMGA2 to elicit epithelial???mesenchymal transition, The Journal of Cell Biology, vol.164, issue.2, pp.175-183, 2006. ,
DOI : 10.1038/sj.emboj.7600069
URL : https://hal.archives-ouvertes.fr/hal-00314880
Transcription factor HNF and hepatocyte differentiation, Hepatology Research, vol.44, issue.10, pp.961-969, 2008. ,
DOI : 10.1111/j.1872-034X.2008.00367.x
Hepatic HNF4alpha deficiency induces periportal expression of glutamine synthetase and other pericentral enzymes, HEPA- TOLOGY, vol.45, pp.433-444, 2007. ,
Behavior of tight-junction, adherens-junction and cell polarity proteins during HNF-4??-induced epithelial polarization, Experimental Cell Research, vol.310, issue.1, pp.66-78, 2005. ,
DOI : 10.1016/j.yexcr.2005.06.025
Integrated approach for the identification of human hepatocyte nuclear factor 4?? target genes using protein binding microarrays, Hepatology, vol.4, issue.9, pp.642-653, 2010. ,
DOI : 10.1002/hep.23357
A Mouse Skin Multistage Carcinogenesis Model Reflects the Aberrant DNA Methylation Patterns of Human Tumors, Cancer Research, vol.64, issue.16, pp.5527-5534, 2004. ,
DOI : 10.1158/0008-5472.CAN-03-4061
Loss of hepatocyte nuclear factor 1?? function in human hepatocellular adenomas leads to aberrant activation of signaling pathways involved in tumorigenesis, Hepatology, vol.15, issue.2, pp.557-566, 2010. ,
DOI : 10.1002/hep.23362
URL : https://hal.archives-ouvertes.fr/hal-01173782