S. C. Silverstein, Endocytic uptake of particles by mononuclear phagocytes and the penetration of obligate intracellular parasites, Am. J. Trop. Med. Hyg, vol.26, pp.161-169, 1977.

O. V. Vieira, R. J. Botelho, and S. Grinstein, Phagosome maturation: aging gracefully, Biochemical Journal, vol.366, issue.3, pp.689-704, 2002.
DOI : 10.1042/bj20020691

I. Jutras, A. Laplante, J. Boulais, S. Brunet, G. Thinakaran et al., ??-Secretase Is a Functional Component of Phagosomes, Journal of Biological Chemistry, vol.280, issue.43, pp.36310-36317, 2005.
DOI : 10.1074/jbc.M504069200

M. Trost, G. Bridon, M. Desjardins, and P. Thibault, Subcellular phosphoproteomics, Mass Spectrometry Reviews, vol.26, issue.Suppl 7, pp.962-990, 2010.
DOI : 10.1002/mas.20297

J. D. Ng-yan-hing, M. Desjardins, and A. Descoteaux, Proteomic analysis reveals a role for protein kinase C-?? in phagosome maturation, Biochemical and Biophysical Research Communications, vol.319, issue.3, pp.810-816, 2004.
DOI : 10.1016/j.bbrc.2004.05.054

URL : https://hal.archives-ouvertes.fr/pasteur-00820046

M. Desjardins, Biogenesis of phagolysosomes: the 'kiss and run' hypothesis, Trends in Cell Biology, vol.5, issue.5, pp.183-186, 1995.
DOI : 10.1016/S0962-8924(00)88989-8

J. Garin, R. Diez, S. Kieffer, J. F. Dermine, S. Duclos et al., The Phagosome Proteome, The Journal of Cell Biology, vol.93, issue.1, pp.165-180, 2001.
DOI : 10.1093/emboj/19.3.349

R. M. Yates, A. Hermetter, and D. G. Russell, The Kinetics of Phagosome Maturation as a Function of Phagosome/Lysosome Fusion and Acquisition of Hydrolytic Activity, Traffic, vol.14, issue.Part 1, pp.413-420, 2005.
DOI : 10.1111/j.1600-0854.2005.00284.x

T. Hunter, Tyrosine phosphorylation: thirty years and counting, Current Opinion in Cell Biology, vol.21, issue.2, pp.140-146, 2009.
DOI : 10.1016/j.ceb.2009.01.028

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670436

N. K. Tonks and B. G. Neel, From Form to Function: Signaling by Protein Tyrosine Phosphatases, Cell, vol.87, issue.3, pp.365-368, 1996.
DOI : 10.1016/S0092-8674(00)81357-4

W. A. Lim and T. Pawson, Phosphotyrosine Signaling: Evolving a New Cellular Communication System, Cell, vol.142, issue.5, pp.661-667, 2010.
DOI : 10.1016/j.cell.2010.08.023

M. Trost, L. English, S. Lemieux, M. Courcelles, M. Desjardins et al., The Phagosomal Proteome in Interferon-??-Activated Macrophages, Immunity, vol.30, issue.1, pp.143-154, 2009.
DOI : 10.1016/j.immuni.2008.11.006

J. V. Olsen, B. Blagoev, F. Gnad, B. Macek, C. Kumar et al., Global, In Vivo, and Site-Specific Phosphorylation Dynamics in Signaling Networks, Cell, vol.127, issue.3, pp.635-648, 2006.
DOI : 10.1016/j.cell.2006.09.026

J. M. Kruger, T. Fukushima, V. Cherepanov, N. Borregaard, C. Loeve et al., Protein-tyrosine Phosphatase MEG2 Is Expressed by Human Neutrophils: LOCALIZATION TO THE PHAGOSOME AND ACTIVATION BY POLYPHOSPHOINOSITIDES, Journal of Biological Chemistry, vol.277, issue.4, pp.2620-2628, 2002.
DOI : 10.1074/jbc.M104550200

H. Huynh, N. Bottini, S. Williams, V. Cherepanov, L. Musumeci et al., Control of vesicle fusion by a tyrosine phosphatase, Nature Cell Biology, vol.235, issue.9, pp.831-839, 2004.
DOI : 10.1083/jcb.17.1.208

K. Saito, S. Williams, A. Bulankina, S. Höning, and T. Mustelin, Association of Protein-tyrosine Phosphatase MEG2 via Its Sec14p Homology Domain with Vesicle-trafficking Proteins, Journal of Biological Chemistry, vol.282, issue.20, pp.15170-15178, 2007.
DOI : 10.1074/jbc.M608682200

I. Abu-dayyeh, M. T. Shio, S. Sato, S. Akira, B. Cousineau et al., Leishmania-Induced IRAK-1 Inactivation Is Mediated by SHP-1 Interacting with an Evolutionarily Conserved KTIM Motif, PLoS Neglected Tropical Diseases, vol.282, issue.2, p.305, 2008.
DOI : 10.1371/journal.pntd.0000305.s009

H. An, J. Hou, J. Zhou, W. Zhao, H. Xu et al., Phosphatase SHP-1 promotes TLR- and RIG-I-activated production of type I interferon by inhibiting the kinase IRAK1, Nature Immunology, vol.19, issue.5, pp.542-550, 2008.
DOI : 10.1038/ni1130

A. O. Hardin, E. A. Meals, T. Yi, K. M. Knapp, and B. K. English, SHP-1 inhibits LPS-mediated TNF and iNOS production in murine macrophages, Biochemical and Biophysical Research Communications, vol.342, issue.2, pp.547-555, 2006.
DOI : 10.1016/j.bbrc.2006.02.005

A. M. Kant, P. De, X. Peng, T. Yi, D. J. Rawlings et al., SHP-1 regulates Fcgamma receptor-mediated phagocytosis and the activation of RAC, Blood, vol.100, pp.1852-1859, 2002.

A. Strzelecka-kiliszek, K. Kwiatkowska, and A. Sobota, Lyn and Syk Kinases Are Sequentially Engaged in Phagocytosis Mediated by Fc??R, The Journal of Immunology, vol.169, issue.12, pp.6787-6794, 2002.
DOI : 10.4049/jimmunol.169.12.6787

J. Boulais, M. Trost, C. R. Landry, R. Dieckmann, E. D. Levy et al., Molecular characterization of the evolution of phagosomes, Molecular Systems Biology, vol.7, p.423, 2010.
DOI : 10.1186/1745-6150-4-9

G. Forget, K. A. Siminovitch, S. Brochu, S. Rivest, D. Radzioch et al., Role of host phosphotyrosine phosphatase SHP-1 in the development of murine leishmaniasis, European Journal of Immunology, vol.110, issue.11, pp.3185-3196, 2001.
DOI : 10.1002/1521-4141(200111)31:11<3185::AID-IMMU3185>3.0.CO;2-J

M. A. Skinner, L. A. Maclaren, and A. G. Wildeman, Stage-dependent Redistribution of the V-ATPase During Bovine Implantation, Journal of Histochemistry & Cytochemistry, vol.267, issue.10, pp.1247-1254, 1999.
DOI : 10.1177/002215549904701004

G. Forget, D. J. Gregory, L. A. Whitcombe, and M. Olivier, Role of Host Protein Tyrosine Phosphatase SHP-1 in Leishmania donovani-Induced Inhibition of Nitric Oxide Production, Infection and Immunity, vol.74, issue.11, pp.6272-6279, 2006.
DOI : 10.1128/IAI.00853-05

A. F. Vinet, M. Fukuda, S. J. Turco, and A. Descoteaux, The Leishmania donovani Lipophosphoglycan Excludes the Vesicular Proton-ATPase from Phagosomes by Impairing the Recruitment of Synaptotagmin V, PLoS Pathogens, vol.36, issue.3, p.1000628, 2009.
DOI : 10.1371/journal.ppat.1000628.s004

A. E. Beaven and K. T. Paynter, Acidification of the Phagosome in Crassostrea virginica Hemocytes Following Engulfment of Zymosan, The Biological Bulletin, vol.196, issue.1, pp.26-33, 1999.
DOI : 10.2307/1543163

M. Rathman, M. D. Sjaastad, and S. Falkow, Acidification of phagosomes containing Salmonella typhimurium in murine macrophages, Infect. Immun, vol.64, pp.2765-2773, 1996.

R. Bjerknes, O. D. Laerum, and W. Knapp, Inhibition of phagocytosis by monoclonal antibodies to human myeloid differentiation antigens, Exp. Hematol, vol.12, pp.856-862, 1984.

A. F. Vinet, M. Fukuda, and A. Descoteaux, The Exocytosis Regulator Synaptotagmin V Controls Phagocytosis in Macrophages, The Journal of Immunology, vol.181, issue.8, pp.5289-5295, 2008.
DOI : 10.4049/jimmunol.181.8.5289

M. A. Gomez, I. Contreras, M. Hallé, M. L. Tremblay, R. W. Mcmaster et al., Leishmania GP63 alters host signaling through cleavageactivated protein tyrosine phosphatases, Sci. Signal, vol.2, p.58, 2009.

K. L. Berg, K. A. Siminovitch, and E. R. Stanley, SHP-1 Regulation of p62DOK Tyrosine Phosphorylation in Macrophages, Journal of Biological Chemistry, vol.274, issue.50, pp.35855-35865, 1999.
DOI : 10.1074/jbc.274.50.35855

O. V. Vieira, C. Bucci, R. E. Harrison, W. S. Trimble, L. Lanzetti et al., Modulation of Rab5 and Rab7 Recruitment to Phagosomes by Phosphatidylinositol 3-Kinase, Molecular and Cellular Biology, vol.23, issue.7, pp.2501-2514, 2003.
DOI : 10.1128/MCB.23.7.2501-2514.2003

S. Saxena, C. Bucci, J. Weis, and A. Kruttgen, The Small GTPase Rab7 Controls the Endosomal Trafficking and Neuritogenic Signaling of the Nerve Growth Factor Receptor TrkA, Journal of Neuroscience, vol.25, issue.47, pp.10930-10940, 2005.
DOI : 10.1523/JNEUROSCI.2029-05.2005

J. F. Dermine, S. Duclos, J. Garin, F. St-louis, S. Rea et al., Flotillin-1-enriched Lipid Raft Domains Accumulate on Maturing Phagosomes, Journal of Biological Chemistry, vol.276, issue.21, pp.18507-18512, 2001.
DOI : 10.1074/jbc.M101113200

C. Alvarez-dominguez, R. Roberts, and P. D. Stahl, Internalized Listeria monocytogenes modulates intracellular trafficking and delays maturation of the phagosome, J. Cell Sci, vol.110, pp.731-743, 1997.

H. J. Ullrich, W. L. Beatty, and D. G. Russell, Direct delivery of procathepsin D to phagosomes: Implications for phagosome biogenesis and parasitism by Mycobacterium, European Journal of Cell Biology, vol.78, issue.10, pp.739-748, 1999.
DOI : 10.1016/S0171-9335(99)80042-9

A. Haas, The Phagosome: Compartment with a License to Kill, Traffic, vol.5, issue.Suppl. 1, pp.311-330, 2007.
DOI : 10.1111/j.1600-0854.2006.00531.x

K. K. Huynh, E. Eskelinen, C. C. Scott, A. Malevanets, P. Saftig et al., LAMP proteins are required for fusion of lysosomes with phagosomes, The EMBO Journal, vol.22, issue.2, pp.313-324, 2007.
DOI : 10.1038/sj.emboj.7601511

M. Majeed, E. Caveggion, C. A. Lowell, and G. Berton, Role of Src kinases and Syk in Fcgamma receptor-mediated phagocytosis and phagosomelysosome fusion, J. Leukoc. Biol, vol.70, pp.801-811, 2001.

S. Greenberg, P. Chang, and S. C. Silverstein, Tyrosine phosphorylation is required for Fc receptor-mediated phagocytosis in mouse macrophages, Journal of Experimental Medicine, vol.177, issue.2, pp.529-534, 1993.
DOI : 10.1084/jem.177.2.529

S. Greenberg, P. Chang, D. C. Wang, R. Xavier, and B. Seed, Clustered syk tyrosine kinase domains trigger phagocytosis., Proc. Natl. Acad. Sci. USA 93, pp.1103-1107, 1996.
DOI : 10.1073/pnas.93.3.1103

URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC40038/pdf

F. Kiefer, J. Brumell, N. Al-alawi, S. Latour, A. Cheng et al., The Syk Protein Tyrosine Kinase Is Essential for Fc?? Receptor Signaling in Macrophages and Neutrophils, Molecular and Cellular Biology, vol.18, issue.7, pp.4209-4220, 1998.
DOI : 10.1128/MCB.18.7.4209

D. Cox, B. M. Dale, M. Kashiwada, C. D. Helgason, and S. Greenberg, A regulatory role for Src homology 2 domain-containing inositol 59-phosphatase (SHIP) in phagocytosis mediated by Fc g receptors and complement receptor 3, J. Exp. Med, vol.11, issue.193, pp.61-71, 2001.

E. García-garcía and C. Rosales, Signal transduction during Fc receptormediated phagocytosis, J. Leukoc. Biol, vol.72, pp.1092-1108, 2002.

J. P. Luzio, V. Poupon, M. R. Lindsay, B. M. Mullock, R. C. Piper et al., Membrane dynamics and the biogenesis of lysosomes (Review), Molecular Membrane Biology, vol.20, issue.2, pp.141-154, 2003.
DOI : 10.1080/0968768031000089546

M. Desjardins, L. A. Huber, R. G. Parton, and G. Griffiths, Biogenesis of phagolysosomes proceeds through a sequential series of interactions with the endocytic apparatus, The Journal of Cell Biology, vol.124, issue.5, pp.677-688, 1994.
DOI : 10.1083/jcb.124.5.677

L. D. Rogers and L. J. Foster, The dynamic phagosomal proteome and the contribution of the endoplasmic reticulum, Proc. Natl. Acad. Sci. USA, pp.18520-18525, 2007.
DOI : 10.1073/pnas.0705801104

S. Duclos, R. Diez, J. Garin, B. Papadopoulou, A. Descoteaux et al., Rab5 regulates the kiss and run fusion between phagosomes and endosomes and the acquisition of phagosome leishmanicidal properties in RAW 264.7 macrophages, J. Cell Sci, vol.113, pp.3531-3541, 2000.

R. E. Harrison, C. Bucci, O. V. Vieira, T. A. Schroer, and S. Grinstein, Phagosomes Fuse with Late Endosomes and/or Lysosomes by Extension of Membrane Protrusions along Microtubules: Role of Rab7 and RILP, Molecular and Cellular Biology, vol.23, issue.18, pp.6494-6506, 2003.
DOI : 10.1128/MCB.23.18.6494-6506.2003

R. S. Flannagan, G. Cosío, and S. Grinstein, Antimicrobial mechanisms of phagocytes and bacterial evasion strategies, Nature Reviews Microbiology, vol.69, issue.5, pp.355-366, 2009.
DOI : 10.1038/nrmicro2128

V. Marshansky and M. Futai, The V-type H+-ATPase in vesicular trafficking: targeting, regulation and function, Current Opinion in Cell Biology, vol.20, issue.4, pp.415-426, 2008.
DOI : 10.1016/j.ceb.2008.03.015

R. M. Yates and D. G. Russell, Phagosome Maturation Proceeds Independently of Stimulation of Toll-like Receptors 2 and 4, Immunity, vol.23, issue.4, pp.409-417, 2005.
DOI : 10.1016/j.immuni.2005.09.007

G. L. Lukacs, O. D. Rotstein, and S. Grinstein, Phagosomal acidification is mediated by a vacuolar-type H(+)-ATPase in murine macrophages, J. Biol. Chem, vol.265, pp.21099-21107, 1990.

R. M. Yates, A. Hermetter, G. A. Taylor, and D. G. Russell, Macrophage Activation Downregulates the Degradative Capacity of the Phagosome, Traffic, vol.101, issue.3, pp.241-250, 2007.
DOI : 10.1111/j.1600-0854.2006.00528.x

G. H. Sun-wada, H. Tabata, N. Kawamura, M. Aoyama, and Y. Wada, Direct recruitment of H+-ATPase from lysosomes for phagosomal acidification, Journal of Cell Science, vol.122, issue.14, pp.2504-2513, 2009.
DOI : 10.1242/jcs.050443

C. Peters, P. D. Andrews, M. J. Stark, S. Cesaro-tadic, A. Glatz et al., Control of the Terminal Step of Intracellular Membrane Fusion by Protein Phosphatase 1&nbsp;, Science, vol.285, issue.5430, pp.1084-1087, 1999.
DOI : 10.1126/science.285.5430.1084

D. Wong, H. Bach, J. Sun, Z. Hmama, Y. Av et al., Mycobacterium tuberculosis protein tyrosine phosphatase (PtpA) excludes host vacuolar-H+-ATPase to inhibit phagosome acidification, Proc. Natl. Acad. Sci. USA, pp.19371-19376, 2011.
DOI : 10.1073/pnas.1109201108

K. Sandvig and B. Van-deurs, Endocytosis, intracellular transport, and cytotoxic action of Shiga toxin and ricin, Physiol. Rev, vol.76, pp.949-966, 1996.

J. M. Muller, J. Shorter, R. Newman, K. Deinhardt, Y. Sagiv et al., Sequential SNARE disassembly and GATE-16???GOS-28 complex assembly mediated by distinct NSF activities drives Golgi membrane fusion, The Journal of Cell Biology, vol.18, issue.7, pp.1161-1173, 2002.
DOI : 10.1038/414652a

M. J. Bayer, C. Reese, S. Bühler, C. Peters, and A. Mayer, Vacuole membrane fusion, The Journal of Cell Biology, vol.267, issue.2, pp.211-222, 2003.
DOI : 10.1016/S0962-8924(01)02003-7

P. R. Hiesinger, A. Fayyazuddin, S. Q. Mehta, T. Rosenmund, K. L. Schulze et al., The v-ATPase V0 Subunit a1 Is Required for a Late Step in Synaptic Vesicle Exocytosis in Drosophila, Cell, vol.121, issue.4, pp.607-620, 2005.
DOI : 10.1016/j.cell.2005.03.012

F. Peri and C. Nüsslein-volhard, Live Imaging of Neuronal Degradation by Microglia Reveals a Role for v0-ATPase a1 in Phagosomal Fusion In Vivo, Cell, vol.133, issue.5, pp.916-927, 2008.
DOI : 10.1016/j.cell.2008.04.037

L. Ren, X. Chen, R. Luechapanichkul, N. G. Selner, T. M. Meyer et al., Substrate Specificity of Protein Tyrosine Phosphatases 1B, RPTP??, SHP-1, and SHP-2, Substrate specificity of protein tyrosine phosphatases 1B, RPTPa, SHP-1, and SHP-2, pp.2339-2356, 2011.
DOI : 10.1021/bi1014453

J. V. Frangioni, P. H. Beahm, V. Shifrin, C. A. Jost, and B. G. Neel, The nontransmembrane tyrosine phosphatase PTP-1B localizes to the endoplasmic reticulum via its 35 amino acid C-terminal sequence, Cell, vol.68, issue.3, pp.545-560, 1992.
DOI : 10.1016/0092-8674(92)90190-N

J. A. Lorenzen, C. Y. Dadabay, and E. H. Fischer, COOH-terminal sequence motifs target the T cell protein tyrosine phosphatase to the ER and nucleus, The Journal of Cell Biology, vol.131, issue.3, pp.631-643, 1995.
DOI : 10.1083/jcb.131.3.631

E. Gagnon, S. Duclos, C. Rondeau, E. Chevet, P. H. Cameron et al., Endoplasmic Reticulum-Mediated Phagocytosis Is a Mechanism of Entry into Macrophages, Cell, vol.110, issue.1, pp.119-131, 2002.
DOI : 10.1016/S0092-8674(02)00797-3

K. M. Heinonen, A. Bourdeau, K. M. Doody, and M. L. Tremblay, Protein tyrosine phosphatases PTP-1B and TC-PTP play nonredundant roles in macrophage development and IFN-?? signaling, Proc. Natl. Acad. Sci. USA, pp.9368-9372, 2009.
DOI : 10.1073/pnas.0812109106

M. Dupuis, M. De-jesús-ibarra-sánchez, M. L. Tremblay, and P. Duplay, Gr-1+ Myeloid Cells Lacking T Cell Protein Tyrosine Phosphatase Inhibit Lymphocyte Proliferation by an IFN-??- and Nitric Oxide-Dependent Mechanism, The Journal of Immunology, vol.171, issue.2, pp.726-732, 2003.
DOI : 10.4049/jimmunol.171.2.726