Night work and the risk of cancer among men.

Abstract : Night work might influence cancer risk, possibly via suppression of melatonin release. In a population-based case-control study conducted in Montreal, Quebec, Canada, between 1979 and 1985, job histories, including work hours, were elicited from 3,137 males with incident cancer at one of 11 anatomic sites and from 512 controls. Compared with men who never worked at night, the adjusted odds ratios among men who ever worked at night were 1.76 (95% confidence interval (CI): 1.25, 2.47) for lung cancer, 2.03 (95% CI: 1.43, 2.89) for colon cancer, 1.74 (95% CI: 1.22, 2.49) for bladder cancer, 2.77 (95% CI: 1.96, 3.92) for prostate cancer, 2.09 (95% CI: 1.40, 3.14) for rectal cancer, 2.27 (95% CI: 1.24, 4.15) for pancreatic cancer, and 2.31 (95% CI: 1.48, 3.61) for non-Hodgkin's lymphoma. Equivocal evidence or no evidence was observed for cancers of the stomach (odds ratio (OR) = 1.34, 95% CI: 0.85, 2.10), kidney (OR = 1.42, 95% CI: 0.86, 2.35), and esophagus (OR = 1.51, 95% CI: 0.80, 2.84) and for melanoma (OR = 1.04, 95% CI: 0.49, 2.22). There was no evidence of increasing risk with increasing duration of night work, with risks generally being increased across all duration categories. Results suggest that night work may increase cancer risk at several sites among men.
Document type :
Journal articles
Complete list of metadatas

Cited literature [55 references]  Display  Hide  Download

https://hal-riip.archives-ouvertes.fr/pasteur-01007614
Contributor : Nancy Laflamme <>
Submitted on : Monday, June 16, 2014 - 8:27:59 PM
Last modification on : Friday, September 20, 2019 - 2:04:05 PM
Long-term archiving on : Tuesday, April 11, 2017 - 7:06:17 AM

File

 Restricted access
To satisfy the distribution rights of the publisher, the document is embargoed until : jamais

Please log in to resquest access to the document

Identifiers

Collections

Citation

Marie-Élise Parent, Mariam El-Zein, Marie-Claude Rousseau, Javier Pintos, Jack Siemiatycki. Night work and the risk of cancer among men.. American Journal of Epidemiology, Oxford University Press (OUP), 2012, 176 (9), pp.751-9. ⟨10.1093/aje/kws318⟩. ⟨pasteur-01007614⟩

Share

Metrics

Record views

460