S. L. Shames, A. H. Fairlamb, A. Cerami, and C. T. Walsh, Purification and characterization of trypanothione reductase from Crithidia fasciculata, a new member of the family of disulfide-containing flavoprotein reductases, Biochemistry, vol.25, issue.12, pp.3519-3526, 1986.
DOI : 10.1021/bi00360a007

G. Colotti and A. Ilari, Polyamine metabolism in Leishmania: from arginine to trypanothione, Amino Acids, vol.272, issue.Pt 2, pp.269-285, 2011.
DOI : 10.1007/s00726-010-0630-3

L. S. Bernardes, C. L. Zani, and I. Carvalho, Trypanosomatidae Diseases: From the Current Therapy to the Efficacious Role of Trypanothione Reductase in Drug Discovery, Current Medicinal Chemistry, vol.20, issue.21, pp.2673-2696, 2013.
DOI : 10.2174/0929867311320210005

P. Baiocco, A. Ilari, P. Ceci, S. Orsini, M. Gramiccia et al., Proliferation, ACS Medicinal Chemistry Letters, vol.2, issue.3, pp.230-233, 2011.
DOI : 10.1021/ml1002629

S. Bonse, J. M. Richards, S. A. Ross, G. Lowe, and R. L. Krauth-siegel, Trypanothione Reductase But Not of Human Glutathione Reductase, Journal of Medicinal Chemistry, vol.43, issue.25, pp.4812-4821, 2000.
DOI : 10.1021/jm000219o

M. Navarro, Gold complexes as potential anti-parasitic agents, Coordination Chemistry Reviews, vol.253, issue.11-12, pp.1619-1626, 2009.
DOI : 10.1016/j.ccr.2008.12.003

A. Ilari, P. Baiocco, L. Messori, A. Fiorillo, A. Boffi et al., A gold-containing drug against parasitic polyamine metabolism: the X-ray structure of trypanothione reductase from Leishmania infantum in complex with auranofin reveals a dual mechanism of enzyme inhibition, Amino Acids, vol.281, issue.3, pp.803-811, 2012.
DOI : 10.1007/s00726-011-0997-9

L. Gabbiani, M. A. Messori, A. Cinellu, P. Casini, A. R. Mura et al., Outstanding plasmodicidal properties within a small panel of metallic compounds: Hints for the development of new metal-based antimalarials, Journal of Inorganic Biochemistry, vol.103, issue.2, pp.310-312, 2008.
DOI : 10.1016/j.jinorgbio.2008.10.004

G. Marcon, S. Carotti, M. Coronnello, L. Messori, E. Mini et al., Gold(III) Complexes with Bipyridyl Ligands:?? Solution Chemistry, Cytotoxicity, and DNA Binding Properties, Journal of Medicinal Chemistry, vol.45, issue.8, pp.1672-1677, 2002.
DOI : 10.1021/jm010997w

M. Serratrice, M. A. Cinellu, L. Maiore, M. Pilo, A. Zucca et al., Synthesis, Structural Characterization, Solution Behavior, and in Vitro Antiproliferative Properties of a Series of Gold Complexes with 2-(2???-Pyridyl)benzimidazole as Ligand: Comparisons of Gold(III) versus Gold(I) and Mononuclear versus Binuclear Derivatives, Inorganic Chemistry, vol.51, issue.5, pp.3161-3171, 2012.
DOI : 10.1021/ic202639t

M. A. Cinellu, L. Maiore, G. Minghetti, F. Cocco, S. Stoccoro et al., Gold(III) Adducts with Chiral Pyridinyl-Oxazolines. Synthesis, Reactivity of the Coordinated Ligands, and Structural Characterizations, Organometallics, vol.28, issue.24, pp.7015-7024, 2009.
DOI : 10.1021/om900841b

L. Maiore, M. A. Cinellu, E. Michelucci, G. Moneti, S. Nobili et al., Structural and solution chemistry, protein binding and antiproliferative profiles of gold(I)/(III) complexes bearing the saccharinato ligand, Journal of Inorganic Biochemistry, vol.105, issue.3, pp.348-355, 2011.
DOI : 10.1016/j.jinorgbio.2010.11.016

A. Casini, M. A. Cinellu, G. Minghetti, C. Gabbiani, M. Coronnello et al., Structural and Solution Chemistry, Antiproliferative Effects, and DNA and Protein Binding Properties of a Series of Dinuclear Gold(III) Compounds with Bipyridyl Ligands, Journal of Medicinal Chemistry, vol.49, issue.18, pp.5524-5531, 2006.
DOI : 10.1021/jm060436a

L. Maiore, M. A. Cinellu, S. Nobili, I. Landini, E. Mini et al., Gold(III) complexes with 2-substituted pyridines as experimental anticancer agents: Solution behavior, reactions with model proteins, antiproliferative properties, Journal of Inorganic Biochemistry, vol.108, pp.123-127, 2012.
DOI : 10.1016/j.jinorgbio.2011.11.007

F. Magherini, A. Modesti, L. Bini, M. Puglia, I. Landini et al., Exploring the biochemical mechanisms of cytotoxic gold compounds: a proteomic study, JBIC Journal of Biological Inorganic Chemistry, vol.49, issue.4, pp.573-582, 2010.
DOI : 10.1007/s00775-010-0624-3

S. Ashutosh, N. Sundar, and . Goyal, Molecular mechanisms of antimony resistance in Leishmania, Journal of Medical Microbiology, vol.56, issue.2, pp.143-153, 2007.
DOI : 10.1099/jmm.0.46841-0

P. Baiocco, S. Franceschini, A. Ilari, and G. Colotti, Trypanothione Reductase from Leishmania infantum: Cloning, Expression, Purification, Crystallization and Preliminary X-Ray Data Analysis, Protein & Peptide Letters, vol.16, issue.2, pp.196-200, 2009.
DOI : 10.2174/092986609787316306