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Journal articles
Autophagy in prostate cancer and androgen suppression therapy.
Abstract : The role of autophagy is known to be highly complex and context-dependent, leading to both cancer suppression and progression in several tumors including melanoma, breast and prostate cancer. In the present review, recent advances in an understanding of the involvement of autophagy in prostate cancer treatment are described. The regulatory effects of androgens on prostate cancer cell autophagy are particularly discussed in order to highlight the effects of autophagy modulation during androgen deprivation. A critical evaluation of the studies examined in the present review suggests the attractive possibility of autophagy inhibition combined with hormonal therapy as a promising approach for prostate cancer treatment.
Cited literature [76 references]
https://hal-riip.archives-ouvertes.fr/pasteur-01026321
Contributor : Istituto Pasteur Fondazione Cenci Bolognetti <>
Submitted on : Monday, July 21, 2014 - 1:26:31 PM
Last modification on : Wednesday, October 28, 2020 - 5:02:02 PM
Long-term archiving on: : Tuesday, April 11, 2017 - 3:28:14 PM
Contributor : Istituto Pasteur Fondazione Cenci Bolognetti <>
Submitted on : Monday, July 21, 2014 - 1:26:31 PM
Last modification on : Wednesday, October 28, 2020 - 5:02:02 PM
Long-term archiving on: : Tuesday, April 11, 2017 - 3:28:14 PM
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Ziparo_et_al.pdf
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