Personal genomes: The case of the missing heritability, Nature, vol.455, issue.7218, pp.18-21, 2008. ,
DOI : 10.1093/hmg/ddm175
Finding the missing heritability of complex diseases, Nature, vol.41, issue.7265, pp.747-53, 2009. ,
DOI : 10.1038/nature08494
Rare Variants Create Synthetic Genome-Wide Associations, PLoS Biology, vol.81, issue.1, p.1000294, 2010. ,
DOI : 10.1371/journal.pbio.1000294.t001
The mystery of missing heritability: Genetic interactions create phantom heritability, Proceedings of the National Academy of Sciences, vol.109, issue.4, pp.1193-1201, 2012. ,
DOI : 10.1073/pnas.1119675109
An Evolutionary Perspective on Epistasis and the Missing Heritability, PLoS Genetics, vol.176, issue.2, p.1003295, 2013. ,
DOI : 10.1371/journal.pgen.1003295.s008
Genetic insights into common pathways and complex relationships among immune-mediated diseases, Nature Reviews Genetics, vol.10, issue.9, pp.661-73, 2013. ,
DOI : 10.1038/ng.2520
Defining the Role of the MHC in Autoimmunity: A Review and Pooled Analysis, PLoS Genetics, vol.450, issue.4, p.1000024, 2008. ,
DOI : 10.1371/journal.pgen.1000024.s010
HLA-B27 and antigen presentation: At the crossroads between immune defense and autoimmunity, Molecular Immunology, vol.57, issue.1, pp.22-29, 2014. ,
DOI : 10.1016/j.molimm.2013.06.017
URL : https://hal.archives-ouvertes.fr/pasteur-01054184
Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility, Nature Genetics, vol.3, issue.8, pp.761-768, 2011. ,
DOI : 10.1093/bioinformatics/btn224
Genome-wide association analysis identifies new susceptibility loci for Beh??et's disease and epistasis between HLA-B*51 and ERAP1, Nature Genetics, vol.335, issue.2, pp.202-209, 2013. ,
DOI : 10.1101/gr.107672.110
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1, Genetic Analysis of Psoriasis Consortium & the Wellcome Trust Case Control Consortium 2, pp.985-90, 2010. ,
DOI : 10.1086/319501
Variants at IRF5-TNPO3, 17q12-21 and MMEL1 are associated with primary biliary cirrhosis, Nature Genetics, vol.81, issue.8, pp.655-662, 2010. ,
DOI : 10.1136/ard.2008.091355
Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis, Nature Genetics, vol.170, issue.8, pp.658-60, 2010. ,
DOI : 10.1182/blood-2009-04-214676
promoter is a strong risk factor for primary Sj??gren's syndrome, Arthritis & Rheumatism, vol.182, issue.7, pp.1991-1998, 2009. ,
DOI : 10.1002/art.24662
Structural insertion/deletion variation in IRF5 is associated with a risk haplotype and defines the precise IRF5 isoforms expressed in systemic lupus erythematosus, Arthritis & Rheumatism, vol.277, issue.4, pp.1234-1275, 2007. ,
DOI : 10.1002/art.22497
A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus, Nature Genetics, vol.40, issue.5, pp.550-555, 2006. ,
DOI : 10.1086/302957
The Systemic Lupus Erythematosus IRF5 Risk Haplotype Is Associated with Systemic Sclerosis, PLoS ONE, vol.360, issue.1, p.54419, 2013. ,
DOI : 10.1371/journal.pone.0054419.s001
RNA-Seq for Enrichment and Analysis of IRF5 Transcript Expression in SLE, PLoS ONE, vol.29, issue.8, p.54487, 2013. ,
DOI : 10.1371/journal.pone.0054487.s009
rs2004640 functional polymorphism and systemic sclerosis: A new perspective for pulmonary fibrosis, Arthritis & Rheumatism, vol.16, issue.Pt 2, pp.225-258, 2009. ,
DOI : 10.1002/art.24183
Phagocytosis Is the Main CR3-Mediated Function Affected by the Lupus-Associated Variant of CD11b in Human Myeloid Cells, PLoS ONE, vol.208, issue.2, p.57082, 2013. ,
DOI : 10.1371/journal.pone.0057082.s004
Single-cell gene expression analysis reveals genetic associations masked in whole-tissue experiments, Nature Biotechnology, vol.467, issue.8, pp.748-52, 2013. ,
DOI : 10.2307/2285891
Enhanced Apoptosis by Disruption of the STAT3-I??B-?? Signaling Pathway in Epithelial Cells Induces Sj??gren???s Syndrome-like Autoimmune Disease, Immunity, vol.38, issue.3, pp.450-60, 2013. ,
DOI : 10.1016/j.immuni.2012.11.016
I??B-?? Deficiency Leaves Epithelial Cells High and Dry, Immunity, vol.38, issue.3, pp.404-410, 2013. ,
DOI : 10.1016/j.immuni.2013.02.016
A Spontaneous Mutation of the Rat Themis Gene Leads to Impaired Function of Regulatory T Cells Linked to Inflammatory Bowel Disease, PLoS Genetics, vol.19, issue.1, p.1002461, 2012. ,
DOI : 10.1371/journal.pgen.1002461.s005
New IBD genetics: common pathways with other diseases, Gut, vol.60, issue.12, pp.1739-53, 2011. ,
DOI : 10.1136/gut.2009.199679
a good candidate susceptibility gene for autoimmune disease?, FEBS Letters, vol.303, issue.23, pp.3689-98, 2011. ,
DOI : 10.1016/j.febslet.2011.04.032
Association between CTLA-4 polymorphisms and susceptibility to Celiac disease: A meta-analysis, Human Immunology, vol.74, issue.9, pp.1214-1222, 2013. ,
DOI : 10.1016/j.humimm.2013.05.014
Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease, Nature, vol.423, issue.6939, pp.506-517, 2003. ,
DOI : 10.1038/nature01621