Service interruption on Monday 11 July from 12:30 to 13:00: all the sites of the CCSD (HAL, EpiSciences, SciencesConf, AureHAL) will be inaccessible (network hardware connection).
Skip to Main content Skip to Navigation
Journal articles

Prevalence of Y chromosome microdeletions in infertile Tunisian men.

Abstract : Yq microdeletions are the leading genetic cause of male infertility and its detection in clinically relevant for appropriate genetic counseling. The objective of this study was to determine the frequency of Y microdeletion in a group of Tunisian infertile men and to compare the prevalence of these abnormalities with other countries and other Tunisian reported series. Totally, 105 Tunisian idiopathic infertile men (74 azoospermic and 31 severe oligozoospermic) were screened for the presence of Y chromosome microdeletions. The screening of Yq microdeletions was performed by two multiplex PCRs using six STS markers recommended by the EAA/EMQN. No microdeletions were detected in the men with severe oligozoospermia. In the azoospermic group, 2/74 (2.7%) patients showed Y chromosome microdeletions. Both had complete deletion of the AZFc region. No microdeletion was identified in the AZFa region or in the AZFb region. The estimated frequency of Y chromosome microdeletions in the present survey was similar to some other reports but lower than that of previous reports in Tunisian populations.
Document type :
Journal articles
Complete list of metadata
Contributor : Institut Pasteur Tunis Connect in order to contact the contributor
Submitted on : Friday, September 5, 2014 - 12:17:31 PM
Last modification on : Wednesday, October 28, 2020 - 9:52:04 AM




Wajih Hammami, Olfa Kilani, Mariem Ben Khelifa, Wiem Ayed, Sonia Abdelhak, et al.. Prevalence of Y chromosome microdeletions in infertile Tunisian men.. Annales de Biologie Clinique, John Libbey Eurotext, 2014, 72 (3), pp.331-6. ⟨10.1684/abc.2014.0962⟩. ⟨pasteur-01061201⟩



Record views