Genetic diversity and population structure of Plasmodium vivax isolates from Sudan, Madagascar, French Guiana and Armenia. - Archive ouverte HAL Access content directly
Journal Articles Infection, Genetics and Evolution Year : 2014

Genetic diversity and population structure of Plasmodium vivax isolates from Sudan, Madagascar, French Guiana and Armenia.

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Abstract

Polymorphic genetic markers and especially microsatellite analysis can be used to investigate multiple aspects of the biology of Plasmodium species. In the current study, we characterized 7 polymorphic microsatellites in a total of 281 Plasmodium vivax isolates to determine the genetic diversity and population structure of P. vivax populations from Sudan, Madagascar, French Guiana, and Armenia. All four parasite populations were highly polymorphic with 3-32 alleles per locus. Mean genetic diversity values was 0.83, 0.79, 0.78 and 0.67 for Madagascar, French Guiana, Sudan, and Armenia, respectively. Significant genetic differentiation between all four populations was observed.
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pasteur-01109682 , version 1 (26-01-2015)

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Michela Menegon, Durand Patrick, Didier Menard, Eric Legrand, Stéphane Picot, et al.. Genetic diversity and population structure of Plasmodium vivax isolates from Sudan, Madagascar, French Guiana and Armenia.. Infection, Genetics and Evolution, 2014, 27, pp.244-9. ⟨10.1016/j.meegid.2014.07.029⟩. ⟨pasteur-01109682⟩
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