Salmonella infections: clinical, immunological, and molecular aspects, 2006. ,
DOI : 10.1017/CBO9780511525360
Revisiting human primary immunodeficiencies, Journal of Internal Medicine, vol.8, issue.2, pp.115-127, 2008. ,
DOI : 10.1111/j.1365-2796.2008.01971.x
Salmonella infections in immunocompromised adults, Journal of Infection, vol.56, issue.6, pp.413-422, 2008. ,
DOI : 10.1016/j.jinf.2008.03.012
From Infectious Diseases to Primary Immunodeficiencies, Immunology and Allergy Clinics of North America, vol.28, issue.2, pp.235-258, 2008. ,
DOI : 10.1016/j.iac.2008.01.009
Iron and microbial infection, Nature Reviews Microbiology, vol.72, issue.12, pp.946-953, 2004. ,
DOI : 10.1172/JCI200420945
Infections and thalassaemia, The Lancet Infectious Diseases, vol.6, issue.4, pp.226-233, 2006. ,
DOI : 10.1016/S1473-3099(06)70437-6
Natural resistance to infection with intracellular parasites: molecular genetics identifies Nramp1 as the Bcg/Ity/Lsh locus, J Leukoc Biol, vol.58, pp.382-390, 1995. ,
), The Journal of Experimental Medicine, vol.5, issue.4, pp.615-625, 1999. ,
DOI : 10.1074/jbc.271.8.4100
infection in mice, The Journal of Experimental Medicine, vol.38, issue.12, pp.2949-2961, 2007. ,
DOI : 10.1093/bioinformatics/btg112
Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene, Science, vol.282, issue.5396, pp.2085-2088, 1998. ,
DOI : 10.1126/science.282.5396.2085
Ankyrins, FEBS Letters, vol.15, issue.1-2, pp.1-5, 2000. ,
DOI : 10.1016/S0014-5793(00)01924-4
Hereditary spherocytosis, The Lancet, vol.372, issue.9647, pp.1411-1426, 2008. ,
DOI : 10.1016/S0140-6736(08)61588-3
Normoblastosis, a murine model for ankyrin-deficient hemolytic anemia, is caused by a hypomorphic mutation in the erythroid ankyrin gene Ank1, The Hematology Journal, vol.4, issue.6, pp.445-449, 2003. ,
DOI : 10.1038/sj.thj.6200307
Novel roles for erythroid Ankyrin-1 revealed through an ENU-induced null mouse mutant, Blood, vol.113, issue.14, pp.3352-3362, 2009. ,
DOI : 10.1182/blood-2008-08-172841
A novel ENU-generated truncation mutation lacking the spectrin-binding and C-terminal regulatory domains of Ank1 models severe hemolytic hereditary spherocytosis, Experimental Hematology, vol.39, issue.3, pp.305-320, 2011. ,
DOI : 10.1016/j.exphem.2010.12.009
A new pale lethal mouse mutation (pale), 2009. ,
A Novel ENU-Mutation in Ankyrin-1 Disrupts Malaria Parasite Maturation in Red Blood Cells of Mice, PLoS ONE, vol.9, issue.6, p.38999, 2012. ,
DOI : 10.1371/journal.pone.0038999.s005
Hematologically important mutations: Ankyrin variants in hereditary spherocytosis, Blood Cells, Molecules, and Diseases, vol.35, issue.3, pp.345-347, 2005. ,
DOI : 10.1016/j.bcmd.2005.08.008
Ankyrin???1 mutations are a major cause of dominant and recessive hereditary spherocytosis, Nature Genetics, vol.76, issue.2, pp.214-218, 1996. ,
DOI : 10.1038/ng0696-214
Molecular Basis of Red Cell Membrane Disorders, Acta Haematologica, vol.108, issue.4, pp.210-218, 2002. ,
DOI : 10.1159/000065657
Targeted disruption of the hepcidin 1 gene results in severe hemochromatosis, Blood, vol.108, issue.4, pp.1402-1405, 2006. ,
DOI : 10.1182/blood-2006-02-003376
N-Ethyl-N-Nitrosourea-Induced Mutation in Ubiquitin-Specific Peptidase 18 Causes Hyperactivation of IFN-???? Signaling and Suppresses STAT4-Induced IFN-?? Production, Resulting in Increased Susceptibility to Salmonella Typhimurium, The Journal of Immunology, vol.185, issue.6, pp.3593-3601, 2010. ,
DOI : 10.4049/jimmunol.1000890
Acquisition of Mn(II) in Addition to Fe(II) Is Required for Full Virulence of Salmonella enterica Serovar Typhimurium, Infection and Immunity, vol.70, issue.11, pp.6032-6042, 2002. ,
DOI : 10.1128/IAI.70.11.6032-6042.2002
Organizing the fluid membrane bilayer: diseases linked to spectrin and ankyrin, Trends in Molecular Medicine, vol.14, issue.1, pp.28-36, 2008. ,
DOI : 10.1016/j.molmed.2007.11.005
Ankyrins: structure and function in normal cells and hereditary spherocytes, Semin Hematol, vol.30, pp.85-118, 1993. ,
Ankyrins. Adaptors between diverse plasma membrane proteins and the cytoplasm, J Biol Chem, vol.267, pp.8703-8706, 1992. ,
Role of the kidney in iron homeostasis: renal expression of Prohepcidin, Ferroportin, and DMT1 in anemic mice, AJP: Renal Physiology, vol.295, issue.4, pp.1213-1221, 2008. ,
DOI : 10.1152/ajprenal.90216.2008
The iron-regulatory peptide hormone hepcidin: expression and cellular localization in the mammalian kidney, Journal of Endocrinology, vol.184, issue.2, pp.361-370, 2005. ,
DOI : 10.1677/joe.1.05729
Iron transport and the kidney, Biochimica et Biophysica Acta (BBA) - General Subjects, vol.1790, issue.7, pp.724-730, 2009. ,
DOI : 10.1016/j.bbagen.2008.10.010
Red cell membrane protein deficiencies in Mexican patients with hereditary spherocytosis, Blood Cells, Molecules, and Diseases, vol.31, issue.3, pp.357-359, 2003. ,
DOI : 10.1016/S1079-9796(03)00207-9
Hereditary spherocytosis: identification of several HS families with ankyrin and band 3 deficiency in a population of southwestern Poland, Annals of Hematology, vol.83, issue.1, pp.28-33, 2004. ,
DOI : 10.1007/s00277-003-0739-5
Anemia, Ineffective Erythropoiesis, and Hepcidin: Interacting Factors in Abnormal Iron Metabolism Leading to Iron Overload in ??-Thalassemia, Hematology/Oncology Clinics of North America, vol.24, issue.6, pp.1089-1107, 2010. ,
DOI : 10.1016/j.hoc.2010.08.003
Effects of iron chelators and iron overload on Salmonella infection, Nature, vol.124, issue.5606, pp.63-65, 1977. ,
DOI : 10.1038/267063a0
Effects of iron overload on the immune system, Ann Clin Lab Sci, vol.30, pp.354-365, 2000. ,
Iron Chelation Via Deferoxamine Exacerbates Experimental Salmonellosis Via Inhibition of the Nicotinamide Adenine Dinucleotide Phosphate Oxidase-Dependent Respiratory Burst, The Journal of Immunology, vol.168, issue.7, pp.3458-3463, 2002. ,
DOI : 10.4049/jimmunol.168.7.3458
Dysfunction of the heme recycling system in heme oxygenase 1-deficient mice: effects on macrophage viability and tissue iron distribution, Blood, vol.116, issue.26, pp.6054-6062, 2010. ,
DOI : 10.1182/blood-2010-03-272138
Hemophagocytic Macrophages Harbor Salmonella enterica during Persistent Infection, PLoS Pathogens, vol.20, issue.12, p.193, 2007. ,
DOI : 10.1371/journal.ppat.0030193.sv003
Malaria impairs resistance to Salmonella through heme- and heme oxygenase???dependent dysfunctional granulocyte mobilization, Nature Medicine, vol.11, issue.1, pp.120-127, 2012. ,
DOI : 10.1074/jbc.272.29.18411
characterization of renal iron transport in the anaesthetized rat, The Journal of Physiology, vol.500, issue.Suppl. 69, pp.581-586, 2000. ,
DOI : 10.1111/j.1469-7793.2000.00581.x
Association of Renal Injury with Increased Oxygen Free Radical Activity and Altered Nitric Oxide Metabolism in Chronic Experimental Hemosiderosis, Laboratory Investigation, vol.80, issue.12, pp.1905-1914, 2000. ,
DOI : 10.1046/j.1523-1755.1999.00670.x
Hepcidin Regulates Cellular Iron Efflux by Binding to Ferroportin and Inducing Its Internalization, Science, vol.306, issue.5704, pp.2090-2093, 2004. ,
DOI : 10.1126/science.1104742
Two to Tango: Regulation of Mammalian Iron Metabolism, Cell, vol.142, issue.1, pp.24-38, 2010. ,
DOI : 10.1016/j.cell.2010.06.028
Hepcidin and iron regulation, 10 years later, Blood, vol.117, issue.17, pp.4425-4433, 2011. ,
DOI : 10.1182/blood-2011-01-258467
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3099567
High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin, Nature Medicine, vol.33, issue.9, pp.1096-1101, 2007. ,
DOI : 10.1038/nm1629
Growth differentiation factor 15 in erythroid health and disease, Current Opinion in Hematology, vol.17, pp.184-190, 2010. ,
DOI : 10.1097/MOH.0b013e328337b52f
The effects of erythropoetic activity and iron burden on hepcidin expression in patients with thalassemia major, Haematologica, vol.91, pp.809-812, 2006. ,
MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-?? superfamily, Proceedings of the National Academy of Sciences, vol.94, issue.21, pp.11514-11519, 1997. ,
DOI : 10.1073/pnas.94.21.11514
Regulation of growth differentiation factor 15 expression by intracellular iron, Blood, vol.113, issue.7, pp.1555-1563, 2009. ,
DOI : 10.1182/blood-2008-07-170431
Absence of functional Hfe protects mice from invasive Salmonella enterica Serovar Typhimurium infection via induction of lipocalin-2, Blood, vol.114, issue.17, pp.3642-3651, 2009. ,
DOI : 10.1182/blood-2009-05-223354
Cellular localization of divalent metal transporter DMT-1 in rat kidney, Am J Physiol Renal Physiol, vol.280, pp.803-814, 2001. ,
Chuvash polycythemia VHLR200W mutation is associated with down-regulation of hepcidin expression, Blood, vol.118, issue.19, pp.5278-5282, 2011. ,
DOI : 10.1182/blood-2011-03-345512
Chronic hepcidin induction causes hyposideremia and alters the pattern of cellular iron accumulation in hemochromatotic mice, Blood, vol.107, issue.7, pp.2952-2958, 2006. ,
DOI : 10.1182/blood-2005-10-4071
Hepcidin as a therapeutic tool to limit iron overload and improve anemia in ??-thalassemic mice, Journal of Clinical Investigation, vol.120, issue.12, pp.4466-4477, 2010. ,
DOI : 10.1172/JCI41717DS1
Minihepcidins prevent iron overload in a hepcidin-deficient mouse model of severe hemochromatosis, Blood, vol.120, issue.18, pp.3829-3836, 2012. ,
DOI : 10.1182/blood-2012-07-440743
Expression and localization of hepcidin in macrophages: a role in host defense against tuberculosis, Journal of Leukocyte Biology, vol.82, issue.4, pp.934-945, 2007. ,
DOI : 10.1189/jlb.0407216
Analysis of cDNA for human erythrocyte ankyrin indicates a repeated structure with homology to tissue-differentiation and cell-cycle control proteins, Nature, vol.344, issue.6261, pp.36-42, 1990. ,
DOI : 10.1038/344036a0