Using the air pouch model for assessing in vivo inflammatory activity of nanoparticles. - RIIP - Réseau International des Instituts Pasteur Accéder directement au contenu
Article Dans Une Revue International Journal of Nanomedicine Année : 2014

Using the air pouch model for assessing in vivo inflammatory activity of nanoparticles.

Denis Girard
  • Fonction : Auteur correspondant
  • PersonId : 928566

Connectez-vous pour contacter l'auteur

Résumé

In this study, Vandooren et al 1 used the air pouch model for evaluating potential pro-inflammatory effects of nanoparticles (NPs). This model is certainly suitable for investigating the inflammatory process which occurs during sterile inflammation and is suitable for determining if an agent, including a given NP, possesses pro-inflammatory activity or not. We have been using the murine air pouch model in our laboratory for more than 12 years. In 2001, we were the first to successfully use this model in an immunotoxi-cogical study to demonstrate that a chemical of environmental concern, the insecticide dieldrin, was found to induce an inflammatory response in vivo, as evidenced by a neutrophilic infiltration into the air pouches.
Fichier principal
Vignette du fichier
IJN-59636-using-the-air-pouch-model-for-assessing-in-vivo-inflammatory_022414.pdf (183.21 Ko) Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)
Loading...

Dates et versions

pasteur-01135680 , version 1 (25-03-2015)

Licence

Paternité - Pas d'utilisation commerciale

Identifiants

Citer

Denis Girard. Using the air pouch model for assessing in vivo inflammatory activity of nanoparticles.. International Journal of Nanomedicine, 2014, 9, pp.1105-7. ⟨10.2147/IJN.S59636⟩. ⟨pasteur-01135680⟩

Collections

RIIP INRS-IAF
45 Consultations
251 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More