E. Albrecht, G. Aberdeen, and G. Pepe, Estrogen Elicits Cortical Zone-Specific Effects on Development of the Primate Fetal Adrenal Gland, Endocrinology, vol.146, issue.4, pp.1737-1744, 2005.
DOI : 10.1210/en.2004-1124

E. Albrecht and G. Pepe, Central integrative role of oestro gen in modulating the communication between the placenta and fetus that results in primate fetal-placental development, Placenta, vol.20, pp.2-3129, 1999.

C. Beaudoin, C. Blomquist, M. Bonenfant, and Y. Tremblay, Expression of the genes for 3 beta-hydroxysteroid dehydrogenase type 1 and cytochrome P450scc during syncytium formation by human placental cytotrophoblast cells in culture and the regulation by progesterone and estradiol, Journal of Endocrinology, vol.154, issue.3, pp.379-387, 1997.
DOI : 10.1677/joe.0.1540379

G. Braunstein, P. Larsen, H. Kronenberg, S. Melmed, and K. Polonsky, Endocrine Changes in Pregnancy, pp.795-810, 2003.
DOI : 10.1016/B978-1-4377-0324-5.00021-3

W. Brown, L. Metzger, J. Barlow, L. Hunsaker, L. Deck et al., 17-??-Hydroxysteroid dehydrogenase type 1: computational design of active site inhibitors targeted to the Rossmann fold, Chemico-Biological Interactions, vol.143, issue.144, pp.143-144481, 2003.
DOI : 10.1016/S0009-2797(02)00184-9

S. Bulun, I. Rosenthal, A. Brodie, S. Inkster, W. Zeller et al., Use of tissue-specific promoters in the regulation of aromatase cytochrome P450 gene expression in human testicular and ovarian sex cord tumors, as well as in normal fetal and adult gonads, J Clin Endocrinol Metab, vol.78, issue.2, pp.1616-1621, 1994.

C. Chevrier, G. Limon, C. Monfort, F. Rouget, R. Garlantézec et al., Urinary Biomarkers of Prenatal Atrazine Exposure and Adverse Birth Outcomes in the PELAGIE Birth Cohort, Environmental Health Perspectives, vol.119, issue.7, pp.1034-1041, 2011.
DOI : 10.1289/ehp.1002775
URL : https://hal.archives-ouvertes.fr/hal-00682592

L. Cronier, J. Guibourdenche, C. Niger, and A. Malassiné, Oestradiol Stimulates Morphological and Functional Differentiation of Human Villous Cytotrophoblast, Placenta, vol.20, issue.8, pp.669-676, 1999.
DOI : 10.1053/plac.1999.0423

W. Fan, T. Yanase, H. Morinaga, S. Gondo, T. Okabe et al., Herbicide atrazine activates SF-1 by direct affinity and concomitant co-activators recruitments to induce aromatase expression via promoter II, Biochemical and Biophysical Research Communications, vol.355, issue.4, pp.1012-1018, 2007.
DOI : 10.1016/j.bbrc.2007.02.062

W. Foster, S. Chan, L. Platt, and C. Hugues, Detection of Endocrine-Disrupting Chemicals in Samples of Second Trimester Human Amniotic Fluid, The Journal of Clinical Endocrinology & Metabolism, vol.85, issue.8, pp.2554-2558, 2000.
DOI : 10.1210/jcem.85.8.6850

A. Gazdar, H. Oie, C. Shackleton, T. Chen, T. Triche et al., Establishment and characterization of a human adrenocortical carcinoma cell line that expresses multiple pathways of steroid biosynthesis, Cancer Res, vol.50, issue.17, pp.5488-5496, 1990.

N. Harada, N. Yoshimura, and S. Honda, Unique regulation of expression of human aromatase in the placenta, The Journal of Steroid Biochemistry and Molecular Biology, vol.86, issue.3-5, pp.3-5327, 2003.
DOI : 10.1016/S0960-0760(03)00375-3

K. Hilscherova, P. Jones, T. Gracia, J. Newsted, X. Zhang et al., Assessment of the Effects of Chemicals on the Expression of Ten Steroidogenic Genes in the H295R Cell Line Using Real-Time PCR, Toxicological Sciences, vol.81, issue.1, pp.78-89, 2004.
DOI : 10.1093/toxsci/kfh191

Y. Ikezuki, O. Tsutsumi, Y. Takai, Y. Kamei, and Y. Taketani, Determination of bisphenol A concentrations in human biological fluids reveals significant early prenatal exposure, Human Reproduction, vol.17, issue.11, pp.2839-2841, 2002.
DOI : 10.1093/humrep/17.11.2839

N. Jablonowski, A. Schaffer, and P. Burauel, Still present after all these years: persistence plus potential toxicity raise questions about the use of atrazine, Environmental Science and Pollution Research, vol.22, issue.1, pp.328-331, 2011.
DOI : 10.1007/s11356-010-0431-y

S. Jaroenporn, C. Furuta, K. Nagaoka, G. Watanabe, and K. Taya, Comparative effects of prolactin versus ACTH, estradiol, progesterone, testosterone, and dihydrotestosterone on cortisol release and proliferation of the adrenocortical carcinoma cell line H295R, Endocrine, vol.41, issue.2, pp.205-209, 2008.
DOI : 10.1007/s12020-008-9075-9

J. Kaludjerovic and W. Ward, The Interplay between Estrogen and Fetal Adrenal Cortex, Journal of Nutrition and Metabolism, vol.5, issue.11, pp.10-1155, 2012.
DOI : 10.1016/j.jsbmb.2004.02.005

P. Kaufmann, S. Black, and B. Huppertz, Endovascular Trophoblast Invasion: Implications for the Pathogenesis of Intrauterine Growth Retardation and Preeclampsia, Biology of Reproduction, vol.69, issue.1, pp.1-7, 2003.
DOI : 10.1095/biolreprod.102.014977

M. Kitada, T. Kamataki, K. Itahashi, T. Rikihisa, and Y. Kanakubo, P-450 HFLa, a form of cytochrome P-450 purified from human fetal livers, is the 16?-hydroxylase of dehydroepiandrosterone 3-sulfate, J Biol Chem, vol.262, issue.28, pp.13534-13537, 1987.

T. Klempan, A. Hudon-thibeault, T. Oufkir, C. Vaillancourt, and J. Sanderson, Stimulation of serotonergic 5-HT2A receptor signaling increases placental aromatase (CYP19) activity and expression in BeWo and JEG-3 human choriocarcinoma cells, Placenta, vol.32, issue.9, pp.651-656, 2011.
DOI : 10.1016/j.placenta.2011.06.003
URL : https://hal.archives-ouvertes.fr/pasteur-00722985

O. Leino, H. Kiviranta, A. Karjalainen, C. Kronberg-kippila, H. Sinkko et al., Pollutant concentrations in placenta, Food and Chemical Toxicology, vol.54, pp.59-69, 2013.
DOI : 10.1016/j.fct.2011.10.058

E. Lephart and E. Simpson, [45] Assay of aromatase activity, Methods Enzymol, vol.206, pp.477-483, 1991.
DOI : 10.1016/0076-6879(91)06116-K

E. Lewintre, M. Orava, H. Peltoketo, and R. Vihko, Characterization of 17??-hydroxysteroid dehydrogenase type 1 in choriocarcinoma cells: regulation by basic fibroblast growth factor, Molecular and Cellular Endocrinology, vol.104, issue.1, pp.1-9, 1994.
DOI : 10.1016/0303-7207(94)90045-0

A. Malassine, J. Frendo, and D. Evain-brion, A comparison of placental development and endocrine functions between the human and mouse model, Human Reproduction Update, vol.9, issue.6, pp.531-539, 2003.
DOI : 10.1093/humupd/dmg043

D. Montanaro, M. Maggiolini, A. Recchia, R. Sirianni, S. Aquila et al., Antiestrogens upregulate estrogen receptor ?? expression and inhibit adrenocortical H295R cell proliferation, Journal of Molecular Endocrinology, vol.35, issue.2, pp.245-256, 2005.
DOI : 10.1677/jme.1.01806

L. Mucci, P. Lagiou, R. Tamimi, C. Hsieh, H. Adami et al., Pregnancy estriol, estradiol, progesterone and prolactin in relation to birth weight and other birth size variables (United States), Cancer Causes and Control, vol.14, issue.4, pp.311-318, 2003.
DOI : 10.1023/A:1023966813330

L. Myatt and K. Sun, Role of fetal membranes in signaling of fetal maturation and parturition, The International Journal of Developmental Biology, vol.54, issue.2-3, pp.2-3545, 2010.
DOI : 10.1387/ijdb.082771lm

P. Myllynen, M. Pasanen, and O. Pelkonen, Human placenta: a human organ for developmental toxicology research and biomonitoring, Placenta, vol.26, issue.5, pp.361-371, 2005.
DOI : 10.1016/j.placenta.2004.09.006

L. Nampoothiri, P. Neelima, and A. Rao, Proteomic profiling of forskolin-induced differentiated BeWo cells: an in-vitro model of cytotrophoblast differentiation, Reproductive BioMedicine Online, vol.14, issue.4, pp.477-487, 2007.
DOI : 10.1016/S1472-6483(10)60896-6

N. Damgaard, I. Main, K. Toppari, J. Skakkebaek, and N. , Impact of exposure to endocrine disrupters inutero and in childhood on adult reproduction, Best Practice & Research Clinical Endocrinology & Metabolism, vol.16, issue.2, pp.289-309, 2002.
DOI : 10.1053/beem.2002.0205

N. Noriega, J. Ostby, C. Lambright, V. Wilson, L. Gray et al., Late Gestational Exposure to the Fungicide Prochloraz Delays the Onset of Parturition and Causes Reproductive Malformations in Male but Not Female Rat Offspring1, Biology of Reproduction, vol.72, issue.6, pp.1324-1335, 2005.
DOI : 10.1095/biolreprod.104.031385

V. Pezzi, J. Mathis, W. Rainey, and B. Carr, Profiling transcript levels for steroidogenic enzymes in fetal tissues, The Journal of Steroid Biochemistry and Molecular Biology, vol.87, issue.2-3, pp.2-3181, 2003.
DOI : 10.1016/j.jsbmb.2003.07.006

D. Poirier, 17??-Hydroxysteroid dehydrogenase inhibitors: a patent review, Expert Opinion on Therapeutic Patents, vol.301, issue.9, pp.1123-1145, 2010.
DOI : 10.1111/j.1749-6632.2009.03702.x

W. Rainey, I. Bird, and J. Mason, The NCI-H295 cell line: a pluripotent model for human adrenocortical studies, Molecular and Cellular Endocrinology, vol.100, issue.1-2, pp.45-50, 1994.
DOI : 10.1016/0303-7207(94)90277-1

W. Rainey, K. Rehman, and B. Carr, Fetal and maternal adrenals in human pregnancy, Obstetrics and Gynecology Clinics of North America, vol.31, issue.4, pp.817-835, 2004.
DOI : 10.1016/j.ogc.2004.08.006

C. Rao, X. Zhou, and Z. Lei, Functional Luteinizing Hormone/Chorionic Gonadotropin Receptors in Human Adrenal Cortical H295R Cells, Biology of Reproduction, vol.71, issue.2, pp.579-587, 2004.
DOI : 10.1095/biolreprod.104.027300

S. Ren and G. Braunstein, Insulin Stimulates Synthesis and Release of Human Chorionic Gonadotropin by Choriocarcinoma Cell Lines, Endocrinology, vol.128, issue.3, pp.1623-1629, 1991.
DOI : 10.1210/endo-128-3-1623

J. Rinsky, C. Hopenhayn, V. Golla, S. Browning, and H. Bush, Atrazine exposure in public drinking water and preterm birth, Public Health Rep, vol.127, issue.1, pp.72-80, 2012.

J. Sanderson, Adrenocortical toxicology in vitro: assessment of steroidogenic enzyme expression and steroid production in H295R cells, In: Adrenal Toxicology, vol.26, pp.175-182, 2009.

J. Sanderson, J. Boerma, G. Lansbergen, and M. Van-den-berg, Induction and Inhibition of Aromatase (CYP19) Activity by Various Classes of Pesticides in H295R Human Adrenocortical Carcinoma Cells, Toxicology and Applied Pharmacology, vol.182, issue.1, pp.44-54, 2002.
DOI : 10.1006/taap.2002.9420

J. Sanderson, J. Hordijk, M. Denison, M. Springsteel, M. Nantz et al., Induction and Inhibition of Aromatase (CYP19) Activity by Natural and Synthetic Flavonoid Compounds in H295R Human Adrenocortical Carcinoma Cells, Toxicological Sciences, vol.82, issue.1, pp.70-79, 2004.
DOI : 10.1093/toxsci/kfh257

J. Sanderson, W. Seinen, J. Giesy, and M. Van-den-berg, 2-Chloro-s-Triazine Herbicides Induce Aromatase (CYP19) Activity in H295R Human Adrenocortical Carcinoma Cells: A Novel Mechanism for Estrogenicity?, Toxicological Sciences, vol.54, issue.1, pp.121-127, 2000.
DOI : 10.1093/toxsci/54.1.121

M. Siddiqui, S. Srivastava, P. Mehrotra, N. Mathur, and I. Tandon, Persistent chlorinated pesticides and intra-uterine foetal growth retardation: a possible association, Int Arch Occup Environ Health, vol.76, issue.1, pp.75-80, 2003.

B. Staels, D. Hum, and W. Miller, Regulation of steroidogenesis in NCI-H295 cells: a cellular model of the human fetal adrenal, Mol Endocrinol, vol.7, pp.423-433, 1993.

S. Stasenko, E. Bradford, M. Piasek, M. Henson, V. Varnai et al., Metals in human placenta: focus on the effects of cadmium on steroid hormones and leptin, Journal of Applied Toxicology, vol.184, issue.10, pp.242-253, 2010.
DOI : 10.1002/jat.1490

W. Stokes, Selecting Appropriate Animal Models and Experimental Designs for Endocrine Disruptor Research and Testing Studies, ILAR Journal, vol.45, issue.4, pp.387-393, 2004.
DOI : 10.1093/ilar.45.4.387
URL : http://ilarjournal.oxfordjournals.org/cgi/content/short/45/4/387

R. Taylor, E. Newman, and S. Chen, Forskolin and methotrexate induce an intermediate trophoblast phenotype in cultured human choriocarcinoma cells, American Journal of Obstetrics and Gynecology, vol.164, issue.1, pp.204-210, 1991.
DOI : 10.1016/0002-9378(91)90654-A

J. Toppari, H. Virtanen, K. Main, and N. Skakkebaek, Cryptorchidism and hypospadias as a sign of testicular dysgenesis syndrome (TDS): Environmental connection, Birth Defects Research Part A: Clinical and Molecular Teratology, vol.13, issue.Suppl 4, pp.910-919, 2010.
DOI : 10.1002/bdra.20707

D. Tulchinsky, C. Hobel, E. Yeager, and J. Marshall, Plasma estrone, estradiol, estriol, progesterone, and 17-hydroxy- progesterone in human pregnancy. I. Normal pregnancy, 1972.

A. Vinggaard, S. Christiansen, P. Laier, M. Poulsen, V. Breinholt et al., Perinatal Exposure to the Fungicide Prochloraz Feminizes the Male Rat Offspring, Toxicological Sciences, vol.85, issue.2, pp.886-897, 2005.
DOI : 10.1093/toxsci/kfi150

A. Vinggaard, C. Nellemann, M. Dalgaard, E. Jørgensen, and H. Andersen, Antiandrogenic Effects in Vitro and in Vivo of the Fungicide Prochloraz, Toxicological Sciences, vol.69, issue.2, pp.344-353, 2002.
DOI : 10.1093/toxsci/69.2.344

M. Watanabe and S. Nakajin, Forskolin up-regulates aromatase (CYP19) activity and gene transcripts in the human adrenocortical carcinoma cell line H295R, Journal of Endocrinology, vol.180, issue.1, pp.125-133, 2004.
DOI : 10.1677/joe.0.1800125

M. Weselak, T. Arbuckle, M. Walker, and D. Krewski, The Influence of the Environment and Other Exogenous Agents on Spontaneous Abortion Risk, Journal of Toxicology and Environmental Health, Part B, vol.65, issue.3-4, pp.3-4221, 2008.
DOI : 10.1016/S0045-6535(01)00073-X

M. Wetendorf and F. Demayo, The progesterone receptor regulates implantation, decidualization, and glandular development via a complex paracrine signaling network, Molecular and Cellular Endocrinology, vol.357, issue.1-2, pp.108-118, 2012.
DOI : 10.1016/j.mce.2011.10.028

Å. Bergman, J. Heindel, S. Jobling, K. Kidd, and R. Zoeller, Geneva:World Health Organization/United Nations Environment Programme, Available, 2013.

R. Yashwanth, S. Rama, A. Anbalagan, and A. Rao, Role of estrogen in regulation of cellular differentiation: A study using human placental and rat Leydig cells, Molecular and Cellular Endocrinology, vol.246, issue.1-2, pp.114-120, 2006.
DOI : 10.1016/j.mce.2005.11.007