Antioxidant Properties of the Flavonoids Silybin and (+)-Cyanidanol-3: Comparison with Butylated Hydroxyanisole and Butylated Hydroxytoluene, Planta Medica, vol.52, issue.06, pp.438-440, 1986. ,
DOI : 10.1055/s-2007-969247
Silybin and the liver: From basic research to clinical practice, World Journal of Gastroenterology, vol.17, issue.18, pp.2288-2301, 2011. ,
DOI : 10.3748/wjg.v17.i18.2288
Silibinin Is a Potent Antiviral Agent in Patients With Chronic Hepatitis C Not Responding to Pegylated Interferon/Ribavirin Therapy, Gastroenterology, vol.135, issue.5, pp.1561-1567, 2008. ,
DOI : 10.1053/j.gastro.2008.07.072
Silibinin and Related Compounds Are Direct Inhibitors of Hepatitis C Virus RNA-Dependent RNA Polymerase, Gastroenterology, vol.138, issue.3, pp.1112-1122, 2010. ,
DOI : 10.1053/j.gastro.2009.11.053
URL : https://hal.archives-ouvertes.fr/inserm-00465965
Milk Thistle (Silybum marianum) for the Therapy of Liver Disease, The American Journal of Gastroenterology, vol.7, issue.2, pp.93-139, 1998. ,
DOI : 10.1016/0006-2952(86)90234-0
Randomized controlled trial of silymarin treatment in patients with cirrhosis of the liver, Journal of Hepatology, vol.9, issue.1, pp.105-113, 1989. ,
DOI : 10.1016/0168-8278(89)90083-4
Chemotherapy of Amanita phalloides Poisoning with Intravenous Silibinin, Human & Experimental Toxicology, vol.2, issue.2, pp.183-195, 1983. ,
DOI : 10.1177/096032718300200203
Silibinin: A novel inhibitor of A?? aggregation, Neurochemistry International, vol.58, issue.3, pp.58-399, 2011. ,
DOI : 10.1016/j.neuint.2010.12.017
Inhibition of human carcinoma cell growth and DNA synthesis by silibinin, an active constituent of milk thistle: comparison with silymarin, Cancer Letters, vol.147, issue.1-2, pp.77-84, 1999. ,
DOI : 10.1016/S0304-3835(99)00276-1
Multitargeted therapy of cancer by silymarin, Cancer Letters, vol.269, issue.2, pp.352-362, 2008. ,
DOI : 10.1016/j.canlet.2008.03.053
Antimetastatic efficacy of silibinin: molecular mechanisms and therapeutic potential against cancer, Cancer and Metastasis Reviews, vol.14, issue.11, pp.447-463, 2010. ,
DOI : 10.1007/s10555-010-9237-0
Targeting silibinin in the antiproliferative pathway, Expert Opinion on Investigational Drugs, vol.10, issue.2, pp.243-255, 2010. ,
DOI : 10.1111/j.1745-7254.2007.00691.x
Silibinin induces protective superoxide generation in human breast cancer MCF-7 cells, Free Radical Research, vol.282, issue.1, pp.44-90, 2010. ,
DOI : 10.3109/10715769209079515
Skin Cancer Chemopreventive Effects of a Flavonoid Antioxidant Silymarin Are Mediated via Impairment of Receptor Tyrosine Kinase Signaling and Perturbation in Cell Cycle Progression, Biochemical and Biophysical Research Communications, vol.247, issue.2, pp.247-294, 1998. ,
DOI : 10.1006/bbrc.1998.8748
Flavonoids as RTK inhibitors and potential anticancer agents, Medicinal Research Reviews, vol.16, issue.8, pp.715-745, 2008. ,
DOI : 10.1002/med.20122
Inhibition Studies of Bovine Xanthine Oxidase by Luteolin, Silibinin, Quercetin, and Curcumin, Journal of Natural Products, vol.72, issue.4, pp.725-731, 2009. ,
DOI : 10.1021/np8007123
Carbonic anhydrase inhibitors. Antioxidant polyphenols effectively inhibit mammalian isoforms I???XV, Bioorganic & Medicinal Chemistry Letters, vol.20, issue.17, pp.5050-5053, 2010. ,
DOI : 10.1016/j.bmcl.2010.07.038
URL : https://hal.archives-ouvertes.fr/hal-00127187
AKR1C3 as a potential target for the inhibitory effect of dietary flavonoids, Chemico-Biological Interactions, vol.178, issue.1-3, pp.138-144, 2009. ,
DOI : 10.1016/j.cbi.2008.10.015
Identification and initial SAR of silybin: An Hsp90 inhibitor, Bioorganic & Medicinal Chemistry Letters, vol.21, issue.9, pp.2659-2664, 2011. ,
DOI : 10.1016/j.bmcl.2010.12.088
Green tea catechins can bind and modify ERp57, Biochim. Biophys. Acta, vol.2013, pp.2671-2682, 1830. ,
The protein disulphide-isomerase family: unravelling a string of folds, Biochemical Journal, vol.339, issue.1, pp.1-10, 1999. ,
DOI : 10.1042/bj3390001
Protein disulphide isomerase: building bridges in protein folding, Trends in Biochemical Sciences, vol.19, issue.8, pp.331-336, 1994. ,
DOI : 10.1016/0968-0004(94)90072-8
Interaction of the Thiol-Dependent Reductase ERp57 with Nascent Glycoproteins, Science, vol.275, issue.5296, pp.86-88, 1997. ,
DOI : 10.1126/science.275.5296.86
Glycoproteins form mixed disulphides with oxidoreductases during folding in living cells, Nature, vol.402, pp.90-93, 1999. ,
ER-60, a chaperone with thiol-dependent reductase activity involved in MHC class I assembly, The EMBO Journal, vol.17, issue.8, pp.2186-2195, 1998. ,
DOI : 10.1093/emboj/17.8.2186
Proteins of the PDI family: Unpredicted non-ER locations and functions, Journal of Cellular Physiology, vol.273, issue.2, pp.154-163, 2002. ,
DOI : 10.1002/jcp.10172
Abstract, Cellular and Molecular Biology Letters, vol.16, issue.4, pp.539-563, 2011. ,
DOI : 10.2478/s11658-011-0022-z
Cooperative activity of Ref-1/APE and ERp57 in reductive activation of transcription factors, Free Radic, Biol. Med, pp.41-1113, 2006. ,
The DNA-binding activity of protein disulfide isomerase ERp57 is associated with the a??? domain, Biochemical and Biophysical Research Communications, vol.295, issue.1, pp.295-67, 2002. ,
DOI : 10.1016/S0006-291X(02)00634-4
The Binding of Antibiotics to ERp57/GRP58, The Journal of Antibiotics, vol.72, issue.6, pp.61-400, 2008. ,
DOI : 10.1038/ja.2008.56
Di-fluoresceinthiocarbamyl-insulin: A Fluorescent Substrate for the Assay of Protein Disulfide Oxidoreductase Activity, Analytical Biochemistry, vol.248, issue.1, pp.94-101, 1997. ,
DOI : 10.1006/abio.1997.2123
Identification and Characterization of Structural Domains of Human ERp57: ASSOCIATION WITH CALRETICULIN REQUIRES SEVERAL DOMAINS, Journal of Biological Chemistry, vol.279, issue.14, pp.279-13607, 2004. ,
DOI : 10.1074/jbc.M313054200
Nuclear localization and DNA interaction of protein disulfide isomerase ERp57 in mammalian cells, Journal of Cellular Biochemistry, vol.273, issue.2, pp.85-325, 2002. ,
DOI : 10.1002/jcb.10137
Bacitracin is not a specific inhibitor of protein disulfide isomerase, FEBS Journal, vol.254, issue.11, pp.2454-2462, 2010. ,
DOI : 10.1111/j.1742-4658.2010.07660.x
Interaction of ERp57 with calreticulin: Analysis of complex formation and effects of vancomycin, Biophysical Chemistry, vol.160, issue.1, pp.160-206, 2012. ,
DOI : 10.1016/j.bpc.2011.09.003
URL : https://hal.archives-ouvertes.fr/pasteur-00960034
Ribozyme knockdown functionally links a 1,25(OH) 2 D3 membrane binding protein (1,25D3-MARRS) and phosphate uptake in intestinal cells, Proc. Natl. Acad. Sci. USA, pp.7392-7397, 2004. ,
Nuclear translocation of the 1,25D3-MARRS (membrane associated rapid response to steroids) receptor protein and NFkB in differentiating NB4 leukemia cells, Exp. Cell Res, pp.316-1101, 2010. ,
Flavonoid???serum albumin complexation: determination of binding constants and binding sites by fluorescence spectroscopy, Biochimica et Biophysica Acta (BBA) - General Subjects, vol.1721, issue.1-3, pp.164-173, 2005. ,
DOI : 10.1016/j.bbagen.2004.10.013
Flavonoid??? Protein Interactions, Flavonoids, Chemistry, Biochemistry and Applications, pp.443-469, 2006. ,
DOI : 10.1201/9781420039443.ch9
Association of solubilized angiotensin II receptors with phospholipase C-a in murine neuroblastoma NIE-115 cells, Mol. Pharmacol, pp.42-217, 1992. ,
Solubilization of rat liver vasopressin receptors as a complex with a guanine-nucleotide-binding protein and phosphoinositide-specific phospholipase C, Biochem. J, vol.261, pp.63-70, 1989. ,
The protein ERp57 contributes to EGF receptor signaling and internalization in MDA-MB-468 breast cancer cells, Journal of Cellular Biochemistry, vol.19, issue.90, 2013. ,
DOI : 10.1002/jcb.24590
Silibinin inhibits constitutive activation of Stat3, and causes caspase activation and apoptotic death of human prostate carcinoma DU145 cells, Carcinogenesis, vol.28, issue.7, pp.1463-1470, 2007. ,
DOI : 10.1093/carcin/bgm042
Association of the Chaperone Glucose-Regulated Protein 58 (GRP58/ER-60/ERp57) with Stat3 in Cytosol and Plasma Membrane Complexes, Journal of Interferon & Cytokine Research, vol.22, issue.5, pp.555-563, 2002. ,
DOI : 10.1089/10799900252982034
Cellular Physiology of STAT3: Where's the Cytoplasmic Monomer?, Journal of Biological Chemistry, vol.274, issue.36, pp.274-25499, 1999. ,
DOI : 10.1074/jbc.274.36.25499
ERp57 is present in STAT3???DNA complexes, Biochemical and Biophysical Research Communications, vol.323, issue.4, pp.323-1306, 2004. ,
DOI : 10.1016/j.bbrc.2004.09.009
Role of ERp57 in the signaling and transcriptional activity of STAT3 in a melanoma cell line, Archives of Biochemistry and Biophysics, vol.494, issue.2, pp.494-178, 2010. ,
DOI : 10.1016/j.abb.2009.12.004
Effect of silibinin in human colorectal cancer cells: Targeting the activation of NF-??B signaling, Molecular Carcinogenesis, vol.94, issue.3, pp.52-195, 2013. ,
DOI : 10.1002/mc.21843
Inhibitory effect of silibinin on ligand binding to erbB1 and associated mitogenic signaling, growth, and DNA synthesis in advanced human prostate carcinoma cells, Molecular Carcinogenesis, vol.60, issue.29, pp.30-224, 2001. ,
DOI : 10.1002/mc.1032
Epidermal Growth Factor Receptor Mediates Silibinin-Induced Cytotoxicity in a Rat Glioma Cell Line, Cancer Biology & Therapy, vol.2, issue.5, pp.526-531, 2003. ,
DOI : 10.4161/cbt.2.5.452