Skip to Main content Skip to Navigation
Journal articles

Therapeutic implications of immunogenic cell death in human cancer

Abstract : Dendritic cells (DCs) are central to the adoptive immune response, and their function is regulated by diverse signals in a context-specific manner. Different DCs have been described in physiologic conditions, inflammation, and cancer, prompting a series of questions on how adoptive immune responses, or tolerance, develop against tumors. Increasing evidence suggests that tumor treatments induce a dramatic change on tumor-infiltrating lymphocytes and, in particular, on some DC subtypes. In this review, we summarize the latest evidence on the role of DCs in cancer and preliminary evidence on chemotherapy-associated antigens identified in human cancers.
Document type :
Journal articles
Complete list of metadata

Cited literature [47 references]  Display  Hide  Download
Contributor : Istituto Pasteur Fondazione Cenci Bolognetti <>
Submitted on : Wednesday, May 6, 2015 - 9:44:54 AM
Last modification on : Wednesday, October 28, 2020 - 3:20:08 PM
Long-term archiving on: : Monday, September 14, 2015 - 7:22:33 PM


Publisher files allowed on an open archive




Fabio Palombo, Chiara Focaccetti, Vincenzo Barnaba, Fabio Palombo, Vincenzo Barnaba. Therapeutic implications of immunogenic cell death in human cancer. Frontiers in Immunology, Frontiers, 2014, pp.6. ⟨10.3389/fimmu.2013.00503⟩. ⟨pasteur-01148979⟩



Record views


Files downloads