An Editing Activity That Prevents Mistranslation and Connection to Disease, Journal of Biological Chemistry, vol.283, issue.43, pp.28777-28782, 2008. ,
DOI : 10.1074/jbc.X800007200
Aminoacyl-tRNA synthesis: divergent routes to a common goal, Trends in Biochemical Sciences, vol.22, issue.2, pp.39-42, 1997. ,
DOI : 10.1016/S0968-0004(96)20033-7
New functions of aminoacyl-tRNA synthetases beyond translation, Nature Reviews Molecular Cell Biology, vol.106, issue.9, pp.668-674, 2010. ,
DOI : 10.1038/nrm2956
The yeast nuclear gene NAM2 is essential for mitochondrial DNA integrity and can cure a mitochondrial RNA-maturase deficiency, Cell, vol.41, issue.1, pp.133-143, 1985. ,
DOI : 10.1016/0092-8674(85)90068-6
A protein required for splicing group I introns in Neurospora mitochondria is mitochondrial tyrosyl-tRNA synthetase or a derivative thereof, Cell, vol.50, issue.3, pp.331-345, 1987. ,
DOI : 10.1016/0092-8674(87)90488-0
Martinis, A prokaryote and human tRNA synthetase provide an essential RNA splicing function in yeast mitochondria, Proc. Natl. Acad. Sci. U. S. A, pp.97-13743, 2000. ,
Peptides from aminoacyl-tRNA synthetases can cure the defects due to mutations in mt tRNA genes, Mitochondrion, vol.11, issue.6, pp.919-923, 2011. ,
DOI : 10.1016/j.mito.2011.08.006
Amati, Isoleucyl?tRNA synthetase levels modulate the penetrance of a homoplasmic m. 4277TNC mitochondrial tRNA(Ile) mutation causing hypertrophic cardiomyopathy, Hum. Mol. Genet, vol.21, pp.85-100, 2012. ,
The isolated carboxyterminal domain of human mitochondrial leucyl?tRNA synthetase rescues the pathological phenotype of mitochondrial tRNA mutations in human cells, EMBO Mol. Med, vol.6, pp.169-182, 2014. ,
URL : https://hal.archives-ouvertes.fr/pasteur-01168181
Human mitochondrial leucyl tRNA synthetase can suppress non cognate pathogenic mt-tRNA mutations, EMBO Molecular Medicine, vol.32, pp.183-193, 2014. ,
DOI : 10.1002/emmm.201303202
Overexpression of human mitochondrial valyl tRNA synthetase can partially restore levels of cognate mt-tRNAVal carrying the pathogenic C25U mutation, Nucleic Acids Research, vol.36, issue.9, pp.3065-3074, 2008. ,
DOI : 10.1093/nar/gkn147
Overexpressed mitochondrial leucyl-tRNA synthetase suppresses the A3243G mutation in the mitochondrial tRNALeu(UUR) gene, RNA, vol.14, issue.11, pp.2407-2416, 2008. ,
DOI : 10.1261/rna.1208808
Human Mitochondrial Leucyl-tRNA Synthetase Corrects Mitochondrial Dysfunctions Due to the tRNALeu(UUR) A3243G Mutation, Associated with Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-Like Symptoms and Diabetes, Molecular and Cellular Biology, vol.30, issue.9, pp.30-2147, 2010. ,
DOI : 10.1128/MCB.01614-09
Can yeast be used to study mitochondrial diseases? Biolistic tRNA mutants for the analysis of mechanisms and suppressors, pp.408-417, 2009. ,
URL : https://hal.archives-ouvertes.fr/hal-00408939
CP1-dependent partitioning of pretransfer and posttransfer editing in leucyl-tRNA synthetase, Proceedings of the National Academy of Sciences, vol.105, issue.49, pp.19223-19228, 2008. ,
DOI : 10.1073/pnas.0809336105
Alteration of the Saccharomyces cerevisiae COX2 mRNA 5'-untranslated leader by mitochondrial gene replacement and functional interaction with the translational activator protein PET111., Molecular Biology of the Cell, vol.4, issue.12, pp.1327-1335, 1993. ,
DOI : 10.1091/mbc.4.12.1327
The yeast counterparts of human ???MELAS??? mutations cause mitochondrial dysfunction that can be rescued by overexpression of the mitochondrial translation factor EF-Tu, EMBO reports, vol.27, issue.1, pp.53-58, 2003. ,
DOI : 10.1038/sj.embor.embor713
Structural and functional role of bases 32 and 33 in the anticodon loop of yeast mitochondrial tRNAIle, RNA, vol.17, issue.11, pp.1983-1996, 2011. ,
DOI : 10.1261/rna.2878711
Reintroduction of a characterized Mit tRNA glycine mutation into yeast mitochondria provides a new tool for the study of human neurodegenerative diseases, Yeast, vol.17, issue.3, pp.219-227, 2001. ,
DOI : 10.1002/1097-0061(200102)18:3<219::AID-YEA651>3.0.CO;2-C
Bolotin-Fukuhara, Ts mutations in mitochondrial tRNA genes: characterization and effects of two point mutations in the mitochondrial gene for tRNAPhe in Saccharomyces cerevisiae, Curr. Genet, pp.33-110, 1998. ,
A point mutation in a mitocbondrial tRNA gene abolishes its 3??? end processing, Nucleic Acids Research, vol.17, issue.14, pp.5751-5764, 1989. ,
DOI : 10.1093/nar/17.14.5751
Yeast as a model of human mitochondrial tRNA base substitutions: Investigation of the molecular basis of respiratory defects, RNA, vol.14, issue.2, pp.275-283, 2008. ,
DOI : 10.1261/rna.740108
URL : https://hal.archives-ouvertes.fr/hal-00196585
Analyzing the suppression of respiratory defects in the yeast model of human mitochondrial tRNA diseases, Gene, vol.527, issue.1, pp.1-9, 2013. ,
DOI : 10.1016/j.gene.2013.05.042
The NAM2 proteins from S. cerevisiae and S. douglasii are mitochondrial leucyl?tRNA synthetases, and are involved in mRNA splicing, EMBO J, vol.7, pp.473-483, 1988. ,
The HTS1 gene encodes both the cytoplasmic and mitochondrial histidine tRNA synthetases of S. cerevisiae, Cell, vol.46, issue.2, pp.235-243, 1986. ,
DOI : 10.1016/0092-8674(86)90740-3
Additional copies of the mitochondrial Ef-Tu and aspartyl?tRNA synthetase genes can compensate for a mutation affecting the maturation of the mitochondrial tRNAAsp, Curr. Genet, pp.31-494, 1997. ,
Saccharomyces cerevisiae imports the cytosolic pathway for Gln-tRNA synthesis into the mitochondrion, Genes & Development, vol.19, issue.5, pp.583-592, 2005. ,
DOI : 10.1101/gad.1269305
Aminoacyl-tRNA synthetases are multivalent suppressors of defects due to human equivalent mutations in yeast mt tRNA genes, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, vol.1803, issue.9, pp.1050-1057, 2010. ,
DOI : 10.1016/j.bbamcr.2010.05.003
Crystallization of RNA and RNA?protein complexes, Methods, vol.34, issue.3, pp.408-414, 2004. ,
DOI : 10.1016/j.ymeth.2004.03.027
The Protein Data Bank, Nucleic Acids Research, vol.28, issue.1, pp.235-242, 2000. ,
DOI : 10.1093/nar/28.1.235
Dictionary of protein secondary structure: Pattern recognition of hydrogen-bonded and geometrical features, Biopolymers, vol.33, issue.12, pp.2577-2637, 1983. ,
DOI : 10.1002/bip.360221211
tRNAdb 2009: compilation of tRNA sequences and tRNA genes, Database issue, pp.159-162, 2009. ,
DOI : 10.1093/nar/gkn772
Universal rules and idiosyncratic features in tRNA identity, Nucleic Acids Research, vol.26, issue.22, pp.5017-5035, 1998. ,
DOI : 10.1093/nar/26.22.5017
Multiple sequence alignment with hierarchical clustering, Nucleic Acids Research, vol.16, issue.22, pp.10881-10890, 1988. ,
DOI : 10.1093/nar/16.22.10881
Compilation of tRNA sequences and sequences of tRNA genes, Nucleic Acids Research, vol.33, issue.Database issue, pp.139-140, 2005. ,
DOI : 10.1093/nar/gki012
URL : https://hal.archives-ouvertes.fr/hal-00356160
Mutations in yeast mt tRNAs: Specific and general suppression by nuclear encoded tRNA interactors, Gene, vol.377, pp.169-176, 2006. ,
DOI : 10.1016/j.gene.2006.04.003
Aminoacylation and conformational properties of yeast mitochondrial tRNA mutants with respiratory deficiency, RNA, vol.11, issue.6, pp.914-927, 2005. ,
DOI : 10.1261/rna.2260305
Purification and characterization of the Saccharomyces cerevisiae mitochondrial leucyltRNA synthetase, J. Biol. Chem, pp.266-2537, 1991. ,
Expression and characterization of the human mitochondrial leucyl-tRNA synthetase, Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, vol.1490, issue.3, pp.245-258, 2000. ,
DOI : 10.1016/S0167-4781(99)00240-7
Martinis, Functional divergence of a unique Cterminal domain of leucyl-tRNA synthetase to accommodate its splicing and aminoacylation roles, J. Biol. Chem, pp.281-23075, 2006. ,
Yeast Mitochondrial Leucyl-tRNA Synthetase CP1 Domain Has Functionally Diverged to Accommodate RNA Splicing at Expense of Hydrolytic Editing, Journal of Biological Chemistry, vol.287, issue.18, pp.287-14772, 2012. ,
DOI : 10.1074/jbc.M111.322412